Reactome | MED30 [nucleoplasm]

MED30 [nucleoplasm]

Stable Identifier

R-HSA-212398

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:Q9Y5B8 NME7

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External Reference Information

External Reference

UniProt:Q96HR3 MED30

Gene Names

MED30, THRAP6, TRAP25

Chain

initiator methionine:, chain:2-178

Reference Genes

BioGPS Gene:90390 MED30

COSMIC (genes):MED30 MED30

CTD Gene:90390 MED30

dbSNP Gene:90390 MED30

ENSEMBL:ENSG00000164758 MED30

HGNC:23032 MED30

KEGG:hsa:90390 MED30

Monarch:90390 MED30

NCBI Gene:90390 MED30

OMIM:610237 MED30

UCSC:Q96HR3 MED30

Reference Transcript

Other Identifiers

11724308_at

17072084

227786_PM_at

227786_at

227787_PM_s_at

227787_s_at

3112714

3112715

3112716

3112720

3112721

3112722

3112723

3112731

3112732

3112733

48578_s_at

48579_r_at

8148022

90390

A_14_P200915

A_23_P31866

GE509363

GO:0000151

GO:0003712

GO:0003713

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0016567

GO:0016592

GO:0016740

GO:0030374

GO:0032968

GO:0035019

GO:0042809

GO:0043226

GO:0045893

GO:0046966

GO:0051123

GO:0060090

GO:0060261

GO:0061630

GO:0065003

GO:0070847

GO:0140096

GO:0140110

HMNXSV003031409

Hs.298229.2.A1_3p_at

ILMN_1671603

PH_hs_0016546

TC08000689.hg

Participates

as a component of

as an input of

Formation of TRAP coactivator complex (Homo sapiens)

Inferred To

med30 [nucleoplasm] (Danio rerio)

MED30 [nucleoplasm] (Bos taurus)

MED30 [nucleoplasm] (Canis familiaris)

MED30 [nucleoplasm] (Drosophila melanogaster)

MED30 [nucleoplasm] (Gallus gallus)

MED30 [nucleoplasm] (Sus scrofa)

Med30 [nucleoplasm] (Rattus norvegicus)

Cross References

OpenTargets

ENSG00000164758

ENSEMBL

ENST00000522839, ENST00000297347, ENSP00000297347, ENSP00000431051, ENSG00000164758

GeneCards

MED30

HPA

ENSG00000164758-MED30

PRO

Q96HR3

Pharos - Targets

Q96HR3

GlyGen

Q96HR3

PDB

8GXS, 7LBM, 7NVR, 8GXQ, 7ENJ, 7ENA, 7ENC, 8TQW, 8TRH, 7EMF, 8T9D

Interactors (37)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.867	8
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.8	9
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.788	6
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.745	7
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.745	8
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.745	6
UniProt:Q9BWU1 CDK19	1	CDK19 [nucleoplasm] (R-HSA-556782)	0.744	6
UniProt:Q9BUE0 MED18	1	MED18 [nucleoplasm] (R-HSA-556826)	0.725	6
UniProt:Q9NWA0 MED9	1	MED9 [nucleoplasm] (R-HSA-556804)	0.725	4
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.725	6
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.725	4
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.643	4
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.643	4
UniProt:Q9NX70 MED29	1	MED29 [nucleoplasm] (R-HSA-556821)	0.643	5
UniProt:Q15528 MED22	1	MED22 [nucleoplasm] (R-HSA-556779)	0.643	4
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.643	4
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.643	3
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.556	5
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:Q9ULW6 NP1L2			0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:Q8IY31-3 IFT20			0.556	3
UniProt:Q9Y5B8 NME7	1	NME7 [cytosol] (R-HSA-6806880)	0.556	5
UniProt:Q8NF50-2 DOCK8			0.556	3
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.527	2
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	2
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.527	2
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	2
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.527	2
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.527	2
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.527	2
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.527	2
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.527	3
UniProt:Q9P086 MED11	1	MED11 [nucleoplasm] (R-HSA-556808)	0.527	2
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.527	2
UniProt:Q9Y6S9 RPKL1			0.499	2
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.483	2

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