Reactome | MED17 [nucleoplasm]

MED17 [nucleoplasm]

Stable Identifier

R-HSA-212401

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:Q9NX70 MED29

Expand all

External Reference Information

External Reference

UniProt:Q9NVC6 MED17

Gene Names

MED17, ARC77, CRSP6, DRIP77, DRIP80, TRAP80

Chain

chain:1-651

Reference Genes

BioGPS Gene:9440 MED17

COSMIC (genes):MED17 MED17

CTD Gene:9440 MED17

dbSNP Gene:9440 MED17

ENSEMBL:ENSG00000042429 MED17

HGNC:2375 MED17

KEGG:hsa:9440 MED17

Monarch:9440 MED17

NCBI Gene:9440 MED17

OMIM:603810 MED17

UCSC:Q9NVC6 MED17

Reference Transcript

RefSeq:NM_004268.4 MED17

Other Identifiers

11718042_at

11718043_a_at

16730124

16730153

221517_PM_s_at

221517_s_at

223115_PM_at

223115_at

232483_PM_at

232483_at

3344898

3344899

3344902

3344903

3344904

3344905

3344906

3344907

3344908

3344909

3344910

3344911

3344912

3344913

3344914

3344915

3344916

3344917

3344918

3344919

3344921

3344922

3344923

3344924

3344925

3344926

3344927

3344928

3344929

3344931

56319_at

61124_at

72039_at

7943176

7943191

7943193

88836_at

9440

A_14_P108974

A_14_P119561

A_23_P116025

A_24_P218587

A_24_P941459

GE55869

GE639667

GE88704

GO:0000151

GO:0003712

GO:0003713

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0005667

GO:0006355

GO:0006357

GO:0006367

GO:0016020

GO:0016567

GO:0016592

GO:0016740

GO:0032968

GO:0035019

GO:0042809

GO:0045893

GO:0045944

GO:0046966

GO:0051123

GO:0060261

GO:0061630

GO:0065003

GO:0070847

GO:0140096

HMNXSV003022957

Hs.22630.1.S2_3p_at

Hs.29438.0.S1_3p_at

ILMN_1730329

PH_hs_0031069

RNA144170|snRNA_123_199

TC11000912.hg

TC11000913.hg

g4838128_3p_a_at

Participates

as a component of

as an input of

Inferred To

MED17 [nucleoplasm] (Bos taurus)

MED17 [nucleoplasm] (Canis familiaris)

MED17 [nucleoplasm] (Drosophila melanogaster)

MED17 [nucleoplasm] (Gallus gallus)

MED17 [nucleoplasm] (Sus scrofa)

Med17 [nucleoplasm] (Mus musculus)

Med17 [nucleoplasm] (Rattus norvegicus)

med17 [nucleoplasm] (Danio rerio)

med17 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_004259.3

OpenTargets

ENSG00000042429

ENSEMBL

ENSP00000251871, ENSG00000042429, ENST00000251871

GeneCards

MED17

HPA

ENSG00000042429-MED17

PRO

Q9NVC6

Pharos - Targets

Q9NVC6

GlyGen

Q9NVC6

Orphanet

MED17

PDB

8GXS, 7ENJ, 8GXQ, 7ENC, 7ENA, 7NVR, 7EMF, 7LBM, 8T9D, 8TRH, 8TQW

Interactors (40)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.927	14
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.886	12
UniProt:Q15528 MED22	1	MED22 [nucleoplasm] (R-HSA-556779)	0.857	8
UniProt:Q9BUE0 MED18	1	MED18 [nucleoplasm] (R-HSA-556826)	0.848	8
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.837	8
UniProt:Q9NX70 MED29	1	MED29 [nucleoplasm] (R-HSA-556821)	0.837	9
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.802	7
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.802	8
UniProt:Q9BWU1 CDK19	1	CDK19 [nucleoplasm] (R-HSA-556782)	0.802	7
UniProt:Q9NWA0 MED9	1	MED9 [nucleoplasm] (R-HSA-556804)	0.788	7
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.788	6
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.788	7
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.745	7
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.745	7
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.744	6
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.725	5
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.725	9
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.725	5
UniProt:Q9P086 MED11	1	MED11 [nucleoplasm] (R-HSA-556808)	0.725	5
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.725	5
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.725	5
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.671	5
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.643	4
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.643	4
UniProt:Q71F56 MED13L	1	MED13L [nucleoplasm] (R-HSA-556797)	0.643	4
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.643	4
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.643	3
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.643	4
UniProt:Q9CQI9 Med30	2	Med30 [nucleoplasm] (R-MMU-9917869) Mediator of RNA polymerase II transcription subunit 30 [nucleoplasm] (R-MMU-556769)	0.589	2
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.527	3
UniProt:Q96RN5 MED15	1	MED15 [nucleoplasm] (R-HSA-556827)	0.527	3
UniProt:O15514 POLR2D	1	POLR2D [nucleoplasm] (R-HSA-63508)	0.527	2
UniProt:P29401 TKT	1	TKT [cytosol] (R-HSA-71321)	0.527	2
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.527	3
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.527	3
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	2
UniProt:O95988 TCL1B			0.527	2
UniProt:P52435 POLR2J	1	POLR2J [nucleoplasm] (R-HSA-63531)	0.527	2
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.527	2
UniProt:Q92731 ESR2	5	ESR2 [cytosol] (R-HSA-9020970) ESR2 [nucleoplasm] (R-HSA-446165) PalmS-ESR2 [cytosol] (R-HSA-9020979) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787)	0.462	2

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