Reactome | MED31 [nucleoplasm]

MED31 [nucleoplasm]

Stable Identifier

R-HSA-212429

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:Q96HR8 NAF1

Expand all

External Reference Information

External Reference

UniProt:Q9Y3C7 MED31

Gene Names

MED31, SOH1, CGI-125

Chain

initiator methionine:, chain:2-131

Reference Genes

BioGPS Gene:51003 MED31

COSMIC (genes):MED31 MED31

CTD Gene:51003 MED31

dbSNP Gene:51003 MED31

ENSEMBL:ENSG00000108590 MED31

HGNC:24260 MED31

KEGG:hsa:51003 MED31

Monarch:51003 MED31

NCBI Gene:51003 MED31

OMIM:620492 MED31

UCSC:Q9Y3C7 MED31

Reference Transcript

RefSeq:NM_016060.2 MED31

Other Identifiers

11734794_a_at

11734795_at

16840408

219318_PM_x_at

219318_x_at

222867_PM_s_at

222867_s_at

236241_PM_at

236241_at

3743166

3743168

3743169

3743174

3743175

3743176

3743177

3743178

3743180

3743181

3743182

3743183

51003

58511_at

8011968

82706_at

A_24_P313678

A_33_P3362526

GE82073

GO:0000151

GO:0003712

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0016567

GO:0016592

GO:0016740

GO:0032968

GO:0043226

GO:0048147

GO:0048856

GO:0051123

GO:0060090

GO:0060173

GO:0060261

GO:0061630

GO:0065003

GO:0070847

GO:0140096

GO:0140110

HMNXSV003058146

Hs.145037.0.A1_3p_at

Hs.27289.0.S1_3p_a_at

ILMN_1756041

PH_hs_0022120

PH_hs_0031192

TC17001066.hg

g7705591_3p_a_at

Participates

as a component of

as an input of

Formation of TRAP coactivator complex (Homo sapiens)

Inferred To

Med31 [nucleoplasm] (Rattus norvegicus)

med31 [nucleoplasm] (Danio rerio)

MED31 [nucleoplasm] (Bos taurus)

MED31 [nucleoplasm] (Canis familiaris)

MED31 [nucleoplasm] (Drosophila melanogaster)

MED31 [nucleoplasm] (Gallus gallus)

MED31 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_057144.1

OpenTargets

ENSG00000108590

ENSEMBL

ENSP00000225728, ENST00000225728

HPA

ENSG00000108590-MED31

PRO

Q9Y3C7

Pharos - Targets

Q9Y3C7

GlyGen

Q9Y3C7

PDB

7NVR, 7ENA, 7ENC, 7LBM, 7EMF, 8GXS, 7ENJ, 8GXQ

Interactors (43)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.867	10
UniProt:Q9BWU1 CDK19	1	CDK19 [nucleoplasm] (R-HSA-556782)	0.848	7
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.837	8
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.802	8
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.798	6
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.745	7
UniProt:Q9BUE0 MED18	1	MED18 [nucleoplasm] (R-HSA-556826)	0.725	7
UniProt:Q9NWA0 MED9	1	MED9 [nucleoplasm] (R-HSA-556804)	0.725	5
UniProt:Q9NX70 MED29	1	MED29 [nucleoplasm] (R-HSA-556821)	0.725	7
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.725	5
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.725	7
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.725	4
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.725	6
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.703	9
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.643	4
UniProt:Q15528 MED22	1	MED22 [nucleoplasm] (R-HSA-556779)	0.643	5
UniProt:Q71F56 MED13L	1	MED13L [nucleoplasm] (R-HSA-556797)	0.643	3
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.643	5
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.643	5
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.643	4
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.615	3
UniProt:Q96HR8 NAF1			0.556	3
UniProt:Q13228 SBP1			0.553	2
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.547	2
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.527	3
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.527	2
UniProt:Q9P086 MED11	1	MED11 [nucleoplasm] (R-HSA-556808)	0.527	2
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.527	3
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.527	3
UniProt:Q92556 ELMO1	1	ELMO1 [cytosol] (R-HSA-200932)	0.527	2
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.527	2
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	2
UniProt:P19387 POLR2C	1	POLR2C [nucleoplasm] (R-HSA-63506)	0.527	2
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.527	3
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.527	3
UniProt:Q86YW9 MD12L			0.527	2
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.527	2
UniProt:P30876 POLR2B	1	POLR2B [nucleoplasm] (R-HSA-63504)	0.527	2
UniProt:P24928 POLR2A	7	POLR2A [nucleoplasm] (R-HSA-63502) p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-113420) p-3S-POLR2A [nucleoplasm] (R-HSA-6797701) Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm] (R-HSA-6781855) p-S5(CTD)-POLR2A [nucleoplasm] (R-HSA-77100) p-S5,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6810226) p-S2,S7(CTD)-POLR2A [nucleoplasm] (R-HSA-6814543)	0.527	2
UniProt:Q96RN5 MED15	1	MED15 [nucleoplasm] (R-HSA-556827)	0.527	2
UniProt:P62487 POLR2G	1	POLR2G [nucleoplasm] (R-HSA-63517)	0.527	2
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.527	2
UniProt:O95257 GA45G			0.508	2

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