Reactome | STRAP [cytosol]

STRAP [cytosol]

Stable Identifier

R-HSA-2127556

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Serine-threonine kinase receptor-associated protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y3F4 STRAP

Gene Names

STRAP, MAWD, UNRIP

Chain

chain:1-350

Reference Genes

BioGPS Gene:11171 STRAP

COSMIC (genes):STRAP STRAP

CTD Gene:11171 STRAP

dbSNP Gene:11171 STRAP

ENSEMBL:ENSG00000023734 STRAP

ENSEMBL_homo_sapiens_GENE:ENSG00000023734.11 STRAP

HGNC:30796 STRAP

KEGG Gene (Homo sapiens):11171 STRAP

Monarch:11171 STRAP

NCBI Gene:11171 STRAP

OMIM:605986 STRAP

UCSC:Q9Y3F4 STRAP

Reference Transcript

RefSeq:NM_007178.3 STRAP

Other Identifiers

11171

11716475_a_at

11751052_a_at

16748751

200870_PM_at

200870_at

3406453

3406454

3406455

3406456

3406457

3406458

3406460

3406462

3406464

3406466

3406467

3406469

3406471

3406474

3406476

3406477

3406478

3406479

3406480

3406481

34402_at

7954173

A_23_P13852

GE53663

GO:0000122

GO:0000380

GO:0000387

GO:0003723

GO:0003729

GO:0005102

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0006351

GO:0006355

GO:0006397

GO:0008380

GO:0016071

GO:0022600

GO:0022618

GO:0023052

GO:0030154

GO:0030182

GO:0030277

GO:0030512

GO:0032797

GO:0034719

GO:0043226

GO:0048856

GO:0065003

GO:1990447

HMNXSV003048465

ILMN_1731194

TC12000205.hg

g6005931_3p_at

Participates

as an input of

STRAP binds phosphorylated TGF-beta receptor complex (Homo sapiens)

as a component of

TGFB1:p-TGFBR:STRAP [plasma membrane] (Homo sapiens)

Inferred To

STRAP [cytosol] (Bos taurus)

STRAP [cytosol] (Canis familiaris)

STRAP [cytosol] (Gallus gallus)

STRAP [cytosol] (Sus scrofa)

strap [cytosol] (Danio rerio)

strap [cytosol] (Xenopus tropicalis)

wmd [cytosol] (Drosophila melanogaster)

Strap [cytosol] (Mus musculus)

Strap [cytosol] (Rattus norvegicus)

Ghost homologue of STRAP [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_009109.3

OpenTargets

ENSG00000023734

HPA

ENSG00000023734-STRAP

GeneCards

Q9Y3F4

Ensembl

ENST00000025399, ENSP00000025399, ENSG00000023734, ENSP00000392270, ENST00000419869

PRO

Q9Y3F4

Pharos - Targets

Q9Y3F4

HMDB Protein

HMDBP14471

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8WXD5 GEMIN6	2	GEMIN6 [nucleoplasm] (R-HSA-191799) GEMIN6 [cytosol] (R-HSA-191771)	0.759	6
UniProt:Q9H840 GEMIN7	2	GEMIN7 [nucleoplasm] (R-HSA-191880) GEMIN7 [cytosol] (R-HSA-191893)	0.759	7
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.725	4
UniProt:P15531 NME1	1	NME1 [cytosol] (R-HSA-60022)	0.668	9
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	4
UniProt:Q9UHI6 DDX20	2	DDX20 [nucleoplasm] (R-HSA-191847) DDX20 [cytosol] (R-HSA-191838)	0.643	4
UniProt:Q8TEQ6 GEMIN5	2	GEMIN5 [cytosol] (R-HSA-191833) GEMIN5 [nucleoplasm] (R-HSA-191765)	0.643	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	17
UniProt:P62316 SNRPD2	2	SNRPD2 [nucleoplasm] (R-HSA-71901) SNRPD2 [cytosol] (R-HSA-191810)	0.59	2
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.59	2
UniProt:Q7Z422-4 SZRD1			0.556	3
UniProt:P11498 PC	3	Btn-PC [cytosol] (R-HSA-3323170) PC [cytosol] (R-HSA-3323119) Btn-PC [mitochondrial matrix] (R-HSA-2993804)	0.527	3
UniProt:Q7Z422-2 SZRD1			0.527	2
UniProt:Q9P2E3 ZNFX1			0.527	3
UniProt:O14519 CDKA1			0.527	3
UniProt:Q15631 TSN	1	TSN [cytosol] (R-HSA-5600685)	0.527	2
UniProt:Q9H3H3 CK068			0.527	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q9BRS8 LARP6			0.527	3
UniProt:Q9NWZ8 GEMIN8	2	GEMIN8 [nucleoplasm] (R-HSA-8932892) GEMIN8 [cytosol] (R-HSA-8932878)	0.527	3
UniProt:O75534 CSDE1			0.527	4
UniProt:Q99598 TSNAX	1	TSNAX [cytosol] (R-HSA-5216130)	0.527	2
UniProt:P57678 GEMIN4	2	GEMIN4 [nucleoplasm] (R-HSA-191841) GEMIN4 [cytosol] (R-HSA-191836)	0.527	3
UniProt:Q9NQG5 RPRD1B	1	RPRD1B [nucleoplasm] (R-HSA-6814894)	0.527	2

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