Reactome | HPR [extracellular region]

HPR [extracellular region]

Stable Identifier

R-HSA-2168854

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Haptoglobin-related protein, HPTR_HUMAN

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Homo sapiens)

- Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
  - Scavenging of heme from plasma (Homo sapiens)
    - Haptoglobin-related Protein binds Hemoglobin (Homo sapiens)
      - HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
        
        HPR Dimer [extracellular region] (Homo sapiens)
        
        HPR [extracellular region] (Homo sapiens)
      - Hemoglobin:HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
        
        HPR:APOL1:APOA1:HDL3 [extracellular region] (Homo sapiens)
        
        HPR Dimer [extracellular region] (Homo sapiens)
        
        HPR [extracellular region] (Homo sapiens)

External Reference Information

External Reference

UniProt:P00739 HPR

Gene Names

HPR

Chain

chain:1-348, signal peptide:1-18

Reference Genes

BioGPS Gene:3250 HPR

COSMIC (genes):HPR HPR

CTD Gene:3250 HPR

dbSNP Gene:3250 HPR

ENSEMBL:ENSG00000261701 HPR

HGNC:5156 HPR

KEGG Gene (Homo sapiens):3250 HPR

Monarch:3250 HPR

NCBI Gene:3250 HPR

OMIM:140210 HPR

UCSC:P00739 HPR

Reference Transcript

RefSeq:NM_020995.3 HPR

Other Identifiers

0003120609

0003840603

11728518_at

16820947

208470_s_at

208471_at

3250

3667859

3667870

3667875

3667877

3667878

3667879

3667883

3667884

3667885

3667892

3667893

3667895

3667896

3667897

3667898

3667899

36983_f_at

36984_f_at

7997192

A_23_P206760

A_23_P421493

A_33_P3289236

GE59631

GO:0002526

GO:0003674

GO:0004252

GO:0005575

GO:0005576

GO:0005615

GO:0006508

GO:0006810

GO:0006898

GO:0006950

GO:0008150

GO:0008219

GO:0008233

GO:0010942

GO:0016192

GO:0030492

GO:0031638

GO:0032991

GO:0034366

GO:0043226

GO:0051604

GO:0070062

GO:0072562

HMNXSV003047722

Hs2Affx.1.389.S1_3p_s_at

ILMN_1809212

ILMN_2155452

K03431_cds1_at

M69197_xpt2_s_at

PH_hs_0030034

PH_hs_0034268

TC16002058.hg

g10337588_3p_at

g10337588_3p_x_at

g4826761_3p_s_at

g4826761_3p_x_at

Participates

as a component of

HPR Dimer [extracellular region] (Homo sapiens)

Inferred To

Homologues of HPR [extracellular region] (Danio rerio)

Homologues of HPR [extracellular region] (Xenopus tropicalis)

C1R [extracellular region] (Gallus gallus)

c1s.2 [extracellular region] (Danio rerio)

c1r [extracellular region] (Danio rerio)

c1r [extracellular region] (Xenopus tropicalis)

Hp [extracellular region] (Mus musculus)

Hp [extracellular region] (Rattus norvegicus)

Cross References

RefSeq

NP_066275.3

OpenTargets

ENSG00000261701

GeneCards

P00739

HPA

ENSG00000261701-HPR

Ensembl

ENST00000540303, ENSP00000441828, ENSG00000261701

PRO

P00739

Pharos - Targets

P00739

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