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RAD51D [nucleoplasm]
Stable Identifier
R-HSA-216920
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA repair protein RAD51 homolog 4, (R51H4) (RAD51-like protein 3) (TRAD), RAD51L3, R51H4, RAD51D
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
HDR through Homologous Recombination (HRR) (Homo sapiens)
D-loop extension by DNA polymerases (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Homologous DNA Pairing and Strand Exchange (Homo sapiens)
CX3 complex binds D-loop structures (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
D-loop formation mediated by PALB2, BRCA2 and RAD51 (Homo sapiens)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Presynaptic phase of homologous DNA pairing and strand exchange (Homo sapiens)
BCDX2 complex formation (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
BCDX2 complex stabilizes RAD51 filament (Homo sapiens)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Resolution of D-Loop Structures (Homo sapiens)
Resolution of D-loop Structures through Holliday Junction Intermediates (Homo sapiens)
BLM mediates dissolution of double Holliday junction (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Cleavage of Holliday junctions by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Homo sapiens)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
FIGNL1 binds RAD51 (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:FIRRM:FIGNL1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Ligation of DNA and formation of Holliday structures following repair synthesis (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
MUS81:EME1,EME2 cleaves D-loop (Homo sapiens)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Resolution of D-loops cleaved by MUS81:EME1 or MUS81:EME2 (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Cleaved D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Resolution of Holliday junctions cleaved by GEN1 or SLX1A:SLX4:MUS81:EME1,(MUS81:EME2) (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Cleaved Holliday Junction:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) (Homo sapiens)
D-loop dissociation and strand annealing (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1:CX3 complex [nucleoplasm] (Homo sapiens)
Extended D-Loop:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-BRCA1-C complex:PALB2:p-T3387-BRCA2:SEM1:p-T309-RAD51:RAD51AP1 [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of DNA repair (Homo sapiens)
Diseases of DNA Double-Strand Break Repair (Homo sapiens)
Defective homologous recombination repair (HRR) due to BRCA1 loss of function (Homo sapiens)
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of BRCA1 in PALB2 binding (Homo sapiens)
Defective 3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Defective homologous recombination repair (HRR) due to BRCA2 loss of function (Homo sapiens)
Impaired BRCA2 binding to PALB2 (Homo sapiens)
Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding (Homo sapiens)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:BRCA2 mutants (PALB2 binding):SEM1:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Defective homologous recombination repair (HRR) due to PALB2 loss of function (Homo sapiens)
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function (Homo sapiens)
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in BRCA1 binding (Homo sapiens)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function (Homo sapiens)
Defective D-loop formation mediated by PALB2, BRCA2 and RAD51 due to loss-of-function of PALB2 in binding to BRCA2/RAD51/RAD51C (Homo sapiens)
3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:p-T309-RAD51:p-T3387-BRCA2:SEM1:BCDX2 complex [nucleoplasm] (Homo sapiens)
BCDX2 complex [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of DNA Repair Genes (Homo sapiens)
CDK12 stimulates expression of DNA repair genes (Homo sapiens)
BRCA1, ATR, FANCD2, FANCI, ATM, MDC1, CHEK1, RAD51D [nucleoplasm] (Homo sapiens)
RAD51D [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75771 RAD51D
Gene Names
RAD51D, RAD51L3
Chain
chain:1-328
Reference Genes
BioGPS Gene:5892 RAD51D
COSMIC (genes):RAD51D RAD51D
CTD Gene:5892 RAD51D
dbSNP Gene:5892 RAD51D
ENSEMBL:ENSG00000185379 RAD51D
ENSEMBL_homo_sapiens_GENE:ENSG00000185379.21 RAD51D
HGNC:9823 RAD51D
KEGG Gene (Homo sapiens):5892 RAD51D
Monarch:5892 RAD51D
NCBI Gene:5892 RAD51D
OMIM:602954 RAD51D
UCSC:O75771 RAD51D
Reference Transcript
RefSeq:NM_001142571.1 RAD51D
RefSeq:NM_002878.3 RAD51D
RefSeq:NM_133629.2 RAD51D
Other Identifiers
11732399_a_at
11751485_a_at
11758494_s_at
16843374
209965_PM_s_at
209965_s_at
3056509
3753405
3753406
3753407
3753408
3753414
3753415
3753416
3753417
3753418
3753419
3753420
3753421
3753422
3753423
3753424
3753425
3753426
3753427
3753428
3753432
3753433
3753434
3753435
3753436
3753437
3753438
3753439
3753440
3753441
3753442
37792_s_at
37793_PM_r_at
37793_r_at
5892
59538_at
8014199
A_23_P500873
A_24_P356509
A_24_P40827
A_32_P120726
A_33_P3210827
GE56475
GE833404
GE856017
GO:0000166
GO:0000400
GO:0000722
GO:0000723
GO:0000724
GO:0000781
GO:0003677
GO:0003697
GO:0003824
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005737
GO:0005813
GO:0005815
GO:0005856
GO:0006259
GO:0006281
GO:0006310
GO:0006974
GO:0007131
GO:0008092
GO:0008094
GO:0016787
GO:0016887
GO:0022414
GO:0032200
GO:0033063
GO:0036297
GO:0042148
GO:0043015
GO:0043226
GO:0050896
GO:0051276
GO:0051726
GO:0140013
GO:0140097
GO:0140299
GO:0140657
GO:0140664
HMNXSV003048312
ILMN_1743356
ILMN_2273921
ILMN_2370907
ILMN_2370910
PH_hs_0007073
TC17001365.hg
TC17002587.hg
TC17002897.hg
g3327885_3p_a_at
g3327885_3p_s_at
Participates
as a candidate of
BRCA1, ATR, FANCD2, FANCI, ATM, MDC1, CHEK1, RAD51D [nucleoplasm] (Homo sapiens)
as an input of
BCDX2 complex formation (Homo sapiens)
as a component of
BCDX2 complex [nucleoplasm] (Homo sapiens)
Inferred To
Ghost homologue of RAD51D [nucleoplasm]
(Rattus norvegicus)
RFFL [nucleoplasm]
(Canis familiaris)
RAD51D [nucleoplasm]
(Bos taurus)
RAD51D [nucleoplasm]
(Gallus gallus)
RAD51D [nucleoplasm]
(Mus musculus)
RAD51D [nucleoplasm]
(Sus scrofa)
Cross References
RefSeq
NP_002869.3
,
NP_598332.1
,
NP_001136043.1
OpenTargets
ENSG00000185379
GeneCards
O75771
HPA
ENSG00000185379-RAD51D
Ensembl
ENST00000345365
,
ENST00000394589
,
ENSP00000338790
,
ENST00000587977
,
ENSP00000378090
,
ENST00000335858
,
ENSP00000465366
,
ENSP00000466399
,
ENSP00000466587
,
ENSP00000465584
,
ENST00000590016
,
ENSP00000338408
,
ENSG00000185379
,
ENST00000588594
,
ENST00000586044
PRO
O75771
Pharos - Targets
O75771
Orphanet
21074
PDB
8OUZ
,
8OUY
,
2KZ3
,
8GBJ
,
8FAZ
Interactors (51)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O43543 XRCC2
1
XRCC2 [nucleoplasm]
(R-HSA-5685302)
0.979
41
UniProt:Q9UKT9 IKZF3
0.849
11
UniProt:Q9Y2J4 AMOTL2
1
AMOTL2 [cytosol]
(R-HSA-2028606)
0.83
8
UniProt:O43502 RAD51C
1
RAD51C [nucleoplasm]
(R-HSA-217039)
0.818
8
UniProt:O15315 RAD51B
1
RAD51B [nucleoplasm]
(R-HSA-983271)
0.81
8
UniProt:Q9BRK4 LZTS2
0.805
9
UniProt:P19012 KRT15
1
KRT15 [cytosol]
(R-HSA-6809589)
0.781
7
UniProt:Q13422 IKZF1
0.742
5
UniProt:Q8IYA8 IHO1
0.718
6
UniProt:Q6P1W5 CA094
0.718
6
UniProt:Q8TBB1 LNX1
1
LNX1 [cytosol]
(R-HSA-8851641)
0.718
6
UniProt:Q9BVG8 KIFC3
0.666
4
UniProt:P54132 BLM
2
4SUMO2,3-BLM [nucleoplasm]
(R-HSA-4568883)
BLM [nucleoplasm]
(R-HSA-174881)
0.639
4
UniProt:Q9H079 KTBL1
0.556
3
UniProt:P57678 GEMIN4
2
GEMIN4 [nucleoplasm]
(R-HSA-191841)
GEMIN4 [cytosol]
(R-HSA-191836)
0.556
3
UniProt:Q8WUT1 Q8WUT1
0.556
3
UniProt:Q9UPT6 JIP3
0.556
3
UniProt:P15884-3 TCF4
0.556
3
UniProt:Q8ND90 PNMA1
0.556
3
UniProt:Q9UK58 CCNL1
0.556
3
UniProt:Q8NI38 IKBD
0.556
3
UniProt:O60504 SORBS3
1
SORBS3 [cytosol]
(R-HSA-445805)
0.556
3
UniProt:Q6P2R3 Q6P2R3
0.556
3
UniProt:Q9Y2B5 VP9D1
0.556
3
IntAct:EBI-16439879 CCSB ORF ID
0.556
3
UniProt:F5H3M2 F5H3M2
0.556
3
UniProt:Q08117-2 TLE5
0.556
3
UniProt:Q5RL73 RBM48
0.556
3
UniProt:Q6P1L6 ZNF343
1
ZNF343 [nucleoplasm]
(R-HSA-1247536)
0.556
3
UniProt:Q9NQX0 PRDM6
0.556
3
UniProt:Q9H0A9-2 SPATC1L
0.556
3
UniProt:O75031 HSF2B
0.556
3
UniProt:O75558 STX11
0.556
3
UniProt:Q53FD0-2 ZC2HC1C
0.556
3
UniProt:Q8IYX8-2 CEP57L1
0.556
3
UniProt:Q8N5R6 CCD33
0.556
3
UniProt:Q14142 TRIM14
1
TRIM14 [cytosol]
(R-HSA-5624345)
0.556
3
UniProt:Q9Y2J4-4 AMOTL2
0.556
3
UniProt:Q04864-2 REL
0.556
3
UniProt:Q5W5X9-3 TTC23
0.556
3
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:Q96N21 AP4AT
0.556
3
UniProt:Q5JST6 EFHC2
0.556
3
UniProt:Q9BVG8-5 KIFC3
0.556
3
UniProt:P48059-3 LIMS1
0.556
3
UniProt:B2RXF5 ZBT42
0.556
3
UniProt:Q13422-7 IKZF1
0.556
3
UniProt:Q6NX45 ZNF774
1
ZNF774 [nucleoplasm]
(R-HSA-3110232)
0.556
3
UniProt:Q9GZV8 PRDM14
1
PRDM14 [nucleoplasm]
(R-HSA-1112608)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:Q6NVH7 SWAP1
0.524
2
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