Collagen type XXIII ectodomain shedding

Stable Identifier
R-HSA-2172405
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Collagen type XXIII is a type II transmembrane collagen with a relatively small ectodomain. It exists in a membrane-bound form and a shed form, cleaved by furin (Veit et al. 2007). Both forms can bind alpha2beta1 integrin via the ectodomain, stimulating the formation of focal adhesion plaques (Veit et al. 2011).
Participants
Participates
Catalyst Activity

serine-type endopeptidase activity of FURIN [plasma membrane]

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Authored
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