NOTCH2 stimulates HES1 transcription

Stable Identifier
R-HSA-2197562
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NOTCH2 stimulates HES1 transcription
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NOTCH2 coactivator complex bound to RBPJ elements in the promoter of HES1 gene stimulates HES1 transcription (Shimizu et al. 2002).
Literature References
PubMed ID Title Journal Year
11866432 Functional diversity among Notch1, Notch2, and Notch3 receptors

Shimizu, K, Hirai, H, Kumano, K, Hamada, Y, Saito, T, Chiba, S

Biochem Biophys Res Commun 2002
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
Active Unit
NOTCH2 Coactivator Complex [nucleoplasm]
Inferred From
Notch2 stimulates Hes1 transcription (Mus musculus)
Authored
Orlic-Milacic, M  (2013-01-11)
Reviewed
Ilagan, MXG  (2013-04-25)
Boyle, S  (2013-04-25)
Created
Orlic-Milacic, M  (2012-04-12)
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