Reactome | Formation of dehydro-lysinonorleucine cross-links

Formation of dehydro-lysinonorleucine cross-links

Stable Identifier

R-HSA-2243931

Type

Reaction [binding]

Species

Homo sapiens

Compartment

extracellular region

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Formation of dehydro-lysinonorleucine cross-links

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Allysine residues can condense with lysine residues forming dehydro-lysinonorleucine (deH-LNL) cross-links. In this representative reaction, all allysine residues are shown as converted to deH-LNL though partial conversion, or conversion to other cross-linked forms is possible (Reiser et al. 1992, Bailey & Peach 1968).

Literature References

PubMed ID	Title	Journal	Year
1348714	Enzymatic and nonenzymatic cross-linking of collagen and elastin Reiser, K, McCormick, RJ, Rucker, RB	FASEB J.	1992
5723342	Isolation and structural identification of a labile intermolecular crosslink in collagen Peach, CM, Bailey, AJ	Biochem Biophys Res Commun	1968