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FTH1 [endocytic vesicle lumen]
Stable Identifier
R-HSA-2299670
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endocytic vesicle lumen
Synonyms
Ferritin heavy chain, FRIH_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging by Class A Receptors (Homo sapiens)
SCARA5:ligand is endocytosed (Homo sapiens)
SCARA5:Ligand [endocytic vesicle membrane] (Homo sapiens)
Ligands of SCARA5 [endocytic vesicle lumen] (Homo sapiens)
Ferritin [endocytic vesicle lumen] (Homo sapiens)
Ferritin Complex Chains [endocytic vesicle lumen] (Homo sapiens)
FTH1 [endocytic vesicle lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P02794 FTH1
Gene Names
FTH1, FTH, FTHL6, OK/SW-cl.84, PIG15
Chain
chain:1-183, initiator methionine:, chain:2-183
Reference Genes
BioGPS Gene:2495 FTH1
COSMIC (genes):FTH1 FTH1
CTD Gene:2495 FTH1
dbSNP Gene:2495 FTH1
ENSEMBL:ENSG00000167996 FTH1
ENSEMBL_homo_sapiens_GENE:ENSG00000167996.16 FTH1
HGNC:3976 FTH1
KEGG Gene (Homo sapiens):2495 FTH1
Monarch:2495 FTH1
NCBI Gene:2495 FTH1
OMIM:134770 FTH1
UCSC:P02794 FTH1
Reference Transcript
RefSeq:NM_002032.2 FTH1
Other Identifiers
11752577_at
11757633_x_at
200748_3p_s_at
200748_PM_s_at
200748_s_at
214211_PM_at
214211_at
2384397
2495
2545844
2545846
2590361
2590364
2629711
2850328
2956776
3142410
31697_s_at
3375649
3375650
3375651
3375652
3375654
3375656
3375657
3375663
3375664
3375665
3375666
33943_at
3505170
3994182
7948656
8170360
A_21_P0013796
A_24_P919330
GE63127
GE81103
GO:0002376
GO:0003824
GO:0004322
GO:0005506
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005764
GO:0005773
GO:0005829
GO:0006826
GO:0006879
GO:0006880
GO:0006955
GO:0008043
GO:0008198
GO:0008199
GO:0008285
GO:0016491
GO:0031410
GO:0042802
GO:0043226
GO:0044754
GO:0046872
GO:0048147
GO:0055065
GO:0070062
GO:0140313
GO:0140315
GO:1904724
GO:1904813
Hs.62954.5.A1_3p_x_at
ILMN_1683146
L20941_at
TC11001860.hg
TC11003179.hg
g4503794_3p_s_at
Participates
as a member of
Ferritin Complex Chains [endocytic vesicle lumen] (Homo sapiens)
Other forms of this molecule
FTH1 [ficolin-1-rich granule lumen]
FTH1 [tertiary granule lumen]
FTH1 [cytosol]
FTH1 [extracellular region]
Cross References
RefSeq
NP_002023.2
OpenTargets
ENSG00000167996
HPA
ENSG00000167996-FTH1
GeneCards
P02794
Ensembl
ENSG00000167996
,
ENST00000273550
,
ENSP00000273550
,
ENSP00000484477
,
ENST00000620041
PRO
P02794
Pharos - Targets
P02794
Orphanet
17368
HMDB Protein
HMDBP08672
PDB
7JGL
,
6B8F
,
6H6T
,
5N26
,
6H6U
,
6KE4
,
6B8G
,
8CPV
,
8AAV
,
2CN7
,
7K3V
,
8PP3
,
5JKM
,
6H5I
,
8CPM
,
4YKH
,
7K3W
,
3AJQ
,
8CPW
,
2CLU
,
6J4A
,
6WYF
,
7JGQ
,
5CMQ
,
6GSR
,
3ERZ
,
8CPU
,
4DYZ
,
8PP2
,
6Z9F
,
8HHS
,
8JAI
,
4OYN
,
6KE2
,
7CK9
,
8B7O
,
6FTV
,
7JGO
,
2CN6
,
5JKK
,
5JKL
,
7JGP
,
3AJO
,
7PF1
,
2Z6M
,
7V66
,
6JPS
,
7A6A
,
7JGK
,
2IU2
,
6JOB
,
3ES3
,
8DHX
,
6M54
,
4DZ0
,
5YI5
,
7R5O
,
5UP8
,
7CK8
,
6WYH
,
8CPT
,
8J9M
,
6Z9E
,
5UP9
,
7KE5
,
5GN8
,
6J7G
,
7JGN
,
5VTD
,
8A5N
,
2CHI
,
8A2M
,
6Z6U
,
6M52
,
2FHA
,
3AJP
,
4DYX
,
4DYY
,
2CEI
,
2CIH
,
5CMR
,
7ZG7
,
5N27
,
7A6B
,
6WYG
,
4Y08
,
6IPO
,
5GOU
,
4ZJK
,
6IPP
,
7JGM
,
7K26
,
6IPQ
,
7RRP
,
5XB1
,
8CPX
,
5ZND
,
7VD8
,
8PP5
,
8A2L
,
1FHA
,
7KE3
,
6IPC
,
8J9L
,
8F49
,
8CPS
,
5UP7
,
8DNP
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9UER7 DAXX
13
monoSUMO1-K630,K631-DAXX [nucleoplasm]
(R-HSA-4086086)
DAXX L98Vfs*13 [nucleoplasm]
(R-HSA-9673102)
DAXX R48Vfs*93 [nucleoplasm]
(R-HSA-9673103)
DAXX C74* [nucleoplasm]
(R-HSA-9673096)
DAXX S138* [nucleoplasm]
(R-HSA-9673081)
DAXX H26Tfs*118 [nucleoplasm]
(R-HSA-9673114)
DAXX E104* [nucleoplasm]
(R-HSA-9673078)
DAXX E72Nfs*72 [nucleoplasm]
(R-HSA-9673110)
DAXX C106* [nucleoplasm]
(R-HSA-9673079)
DAXX A103Sfs*40 [nucleoplasm]
(R-HSA-9673121)
DAXX K56* [nucleoplasm]
(R-HSA-9673089)
DAXX A36Qfs*108 [nucleoplasm]
(R-HSA-9673105)
DAXX [nucleoplasm]
(R-HSA-3222068)
0.691
5
UniProt:Q92574 TSC1
2
TSC1 [plasma membrane]
(R-HSA-165169)
TSC1 [cytosol]
(R-HSA-5672338)
0.635
3
UniProt:O95429 BAG4
3
BAG4 [cytosol]
(R-HSA-5212670)
BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853156)
BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane]
(R-HSA-8853157)
0.601
4
UniProt:P02753 RBP4
3
RBP4 G75D [extracellular region]
(R-HSA-2471928)
RBP4 I41N [extracellular region]
(R-HSA-2471954)
RBP4(19-201) [extracellular region]
(R-HSA-2453675)
0.527
2
UniProt:Q9Y337 KLK5
4
KLK5 [extracellular region]
(R-HSA-8849629)
proKLK5 [extracellular region]
(R-HSA-8849836)
KLK5 propeptide [extracellular region]
(R-HSA-8849839)
KLK5 [cytosol]
(R-HSA-8934778)
0.527
2
UniProt:P07476 IVL
2
IVL [cornified envelope]
(R-HSA-8847720)
IVL [cytosol]
(R-HSA-6810837)
0.527
2
UniProt:O60437 PPL
2
PPL [cytosol]
(R-HSA-6810850)
PPL [cornified envelope]
(R-HSA-8847709)
0.527
2
UniProt:P22735 TGM1
3
TGM1 [cytosol]
(R-HSA-6813756)
TGM1 [cornified envelope]
(R-HSA-8847706)
TGM1 [plasma membrane]
(R-HSA-6813757)
0.527
2
UniProt:P42357 HAL
1
HAL [cytosol]
(R-HSA-70897)
0.527
2
UniProt:P20930 FLG
2
FLG(?-?) [cytosol]
(R-HSA-6810859)
FLG(1-4061) [cytosol]
(R-HSA-8849818)
0.527
2
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.508
2
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