Reactome | DAG1(30-653) [extracellular region]

DAG1(30-653) [extracellular region]

Stable Identifier

R-HSA-2328152

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Alpha-dystroglycan, Dystroglycan alpha, DAG1_HUMAN, DAG1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14118 DAG1

Gene Names

DAG1

Chain

signal peptide:1-29, chain:30-653, chain:654-895

Reference Genes

COSMIC (genes):DAG1 DAG1

dbSNP Gene:1605 DAG1

ENSEMBL:ENSG00000173402 DAG1

Participates

as a component of

as an input of

AGRN binds Alpha-dystroglycan (Homo sapiens)

Other forms of this molecule

DAG1 [endoplasmic reticulum membrane]

DAG1(654-895) [endoplasmic reticulum membrane]

DAG1(654-895) [Golgi membrane]

GlcNAc-1,6-(GlcNAc-1,2)-Man-DAG1 [Golgi lumen]

GlcNAc-1,6-(GlcNAc-1,2)-Man-DAG1 [extracellular region]

GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen]

GlcNAc,1,2-Man-DAG1 [Golgi lumen]

Man-DAG1 [Golgi lumen]

GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]

GlcNAc-Man-DAG1 [endoplasmic reticulum lumen]

Man-DAG1 [endoplasmic reticulum lumen]

DAG1(30-653) [endoplasmic reticulum lumen]

DAG1(30-653) [cytosol]

DAG1(654-895) [plasma membrane]

Inferred To

Dag1 [extracellular region] (Mus musculus)

DAG1(30-653) [extracellular region] (Gallus gallus)

Dg [extracellular region] (Drosophila melanogaster)

DAG1 [extracellular region] (Bos taurus)

DAG1 [extracellular region] (Canis familiaris)

DAG1 [extracellular region] (Sus scrofa)

dgn-1 [extracellular region] (Caenorhabditis elegans)

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14118 DAG1	15	DAG1 [endoplasmic reticulum membrane] (R-HSA-9913254) DAG1(654-895) [endoplasmic reticulum membrane] (R-HSA-9913257) DAG1(654-895) [Golgi membrane] (R-HSA-9913184) GlcNAc-1,6-(GlcNAc-1,2)-Man-DAG1 [Golgi lumen] (R-HSA-8932424) GlcNAc-1,6-(GlcNAc-1,2)-Man-DAG1 [extracellular region] (R-HSA-9913190) GalNAc-GlcNAc-Man6P-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931659) GlcNAc,1,2-Man-DAG1 [Golgi lumen] (R-HSA-5617087) Man-DAG1 [Golgi lumen] (R-HSA-8931888) GalNAc-GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931656) GlcNAc-Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-8931673) Man-DAG1 [endoplasmic reticulum lumen] (R-HSA-5615647) DAG1(30-653) [endoplasmic reticulum lumen] (R-HSA-8931890) DAG1(30-653) [cytosol] (R-HSA-5615641) DAG1(30-653) [extracellular region] (R-HSA-2328152) DAG1(654-895) [plasma membrane] (R-HSA-2328154)	0.558	2
UniProt:P33151 CDH5	2	p-S665-VE-cadherin [plasma membrane] (R-HSA-5357435) VE-cadherin [plasma membrane] (R-HSA-418992)	0.527	2
UniProt:O00214 LEG8			0.527	2
UniProt:Q9NU53 GINM1			0.527	2
UniProt:Q8WXA8 HTR3C	1	HTR3C [plasma membrane] (R-HSA-975312)	0.527	2
UniProt:O95302 FKBP9	1	FKBP9 [cytosol] (R-HSA-391306)	0.527	2
UniProt:Q9Y5F2 PCDBB			0.527	2
UniProt:P01375 TNF	5	TNF(1-233) [plasma membrane] (R-HSA-66220) TNF(77-233) [extracellular region] (R-HSA-976821) TNF(1-76) [plasma membrane] (R-HSA-8863120) TNF(1-34) [plasma membrane] (R-HSA-8863367) TNF(52-76) [extracellular region] (R-HSA-8863375)	0.527	2
UniProt:Q96GX1 TCTN2	1	TCTN2 [ciliary membrane] (R-HSA-5626661)	0.527	2
UniProt:P20036 HLA-DPA1	9	HLA class II histocompatibility antigen, DP alpha chain precursor [plasma membrane] (R-HSA-197586) HLA class II histocompatibility antigen, DP alpha chain precursor [lysosomal membrane] (R-HSA-2130639) HLA class II histocompatibility antigen, DP alpha chain precursor [endocytic vesicle membrane] (R-HSA-2130435) HLA class II histocompatibility antigen, DP alpha chain precursor [clathrin-coated endocytic vesicle membrane] (R-HSA-2130485) HLA class II histocompatibility antigen, DP alpha chain precursor [transport vesicle membrane] (R-HSA-2130648) HLA class II histocompatibility antigen, DP alpha chain precursor [trans-Golgi network membrane] (R-HSA-2130337) HLA class II histocompatibility antigen, DP alpha chain precursor [Golgi membrane] (R-HSA-2214387) HLA class II histocompatibility antigen, DP alpha chain precursor [ER to Golgi transport vesicle membrane] (R-HSA-2130739) HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (R-HSA-2130667)	0.527	2
UniProt:P32971 TNFSF8	1	TNFSF8 [plasma membrane] (R-HSA-5667148)	0.527	3
UniProt:P46939 UTRN	1	UTRN [cytosol] (R-HSA-5216039)	0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:P21926 CD9	4	CD9 [plasma membrane] (R-HSA-51717) CD9 [endocytic vesicle membrane] (R-HSA-5334774) CD9 [clathrin-coated endocytic vesicle membrane] (R-HSA-5334779) CD9 [platelet alpha granule membrane] (R-HSA-114585)	0.462	2

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