Nascent CMs transform into mature CMs

Stable Identifier
R-HSA-2395784
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region
ReviewStatus
5/5
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Nascent CMs transform into mature CMs
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Nascent chylomicrons (CMs) acquire copies of apolipoproteins C-II, C-III, and E from circulating spherical (mature) high-density lipoprotein particles, becoming mature chylomicrons (Havel et al. 1973, Bisgaier & Glickman 1983). Here, this interaction is annotated to involve the transfer of a single copy of each lipoprotein, but a mature chylomicron in fact contains approximately 25 copies of apolipoprotein E and 180 copies of C apolipoproteins (Bhattacharya & Redgrave 1981).
Literature References
PubMed ID Title Journal Year
4345202 Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man

Havel, RJ, Kashyap, ML, Kane, JP

J Clin Invest 1973
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Orthologous Events
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Authored
Jassal, B  (2012-07-02)
Reviewed
Blaner, WS  (2013-01-31)
Created
Jassal, B  (2012-07-02)
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