Reactome | MFAP1 [extracellular region]

MFAP1 [extracellular region]

Stable Identifier

R-HSA-2396419

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Microfibrillar-associated protein 1, MFAP1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P55081 MFAP1

Gene Names

MFAP1

Chain

initiator methionine:1, chain:2-439

Reference Genes

BioGPS Gene:4236 MFAP1

COSMIC (genes):MFAP1 MFAP1

CTD Gene:4236 MFAP1

dbSNP Gene:4236 MFAP1

ENSEMBL:ENSG00000140259 MFAP1

HGNC:7032 MFAP1

KEGG Gene (Homo sapiens):4236 MFAP1

Monarch:4236 MFAP1

NCBI Gene:4236 MFAP1

OMIM:600215 MFAP1

UCSC:P55081 MFAP1

Reference Transcript

RefSeq:NM_005926.2 MFAP1

Other Identifiers

0003170471

11721251_at

16808386

203406_at

3621693

3621694

3621695

3621696

3621697

3621698

3621699

3621701

3621706

3621708

3621709

3621710

3621711

3621712

3621713

3621716

3621718

3621719

3621720

3621721

36535_at

4236

7988245

A_23_P14636

GE58872

GO:0000398

GO:0001527

GO:0003674

GO:0003723

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005634

GO:0005654

GO:0005681

GO:0005684

GO:0005813

GO:0005815

GO:0005856

GO:0006397

GO:0008150

GO:0008380

GO:0031012

GO:0032991

GO:0034641

GO:0043226

GO:0071005

HMNXSV003037803

ILMN_1676799

PH_hs_0003900

PH_hs_0031276

TC15001287.hg

U04209_at

g5174552_3p_at

Participates

as a member of

Elastic fibre-asociated proteins [extracellular region] (Homo sapiens)

Inferred To

Mfap1b [extracellular region] (Mus musculus)

mfap1 [extracellular region] (Danio rerio)

mfap1 [extracellular region] (Xenopus tropicalis)

Homologues of MFAP1 [extracellular region] (Mus musculus)

Mfap1a [extracellular region] (Mus musculus)

MFAP1 [extracellular region] (Bos taurus)

MFAP1 [extracellular region] (Canis familiaris)

MFAP1 [extracellular region] (Gallus gallus)

MFAP1 [extracellular region] (Sus scrofa)

Cross References

RefSeq

NP_005917.2

OpenTargets

ENSG00000140259

GeneCards

P55081

HPA

ENSG00000140259-MFAP1

Ensembl

ENSP00000267812, ENSG00000140259, ENST00000267812

PRO

P55081

Pharos - Targets

P55081

GlyGen

P55081

PDB

6AHD, 7ABG, 5O9Z, 7AAV, 5F5S, 7ABI, 7ABF

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:Q9Y6D9 MAD1L1	1	MAD1L1 [cytosol] (R-HSA-141433)	0.718	6
UniProt:Q9H257 CARD9	3	CARD9 [cytosol] (R-HSA-561194) p-T231-CARD9 [plasma membrane] (R-HSA-5607623) CARD9 [plasma membrane] (R-HSA-5607662)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.556	3
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:Q96CW1 AP2M1	6	AP2M1 [cytosol] (R-HSA-182227) AP2M1 [clathrin-coated endocytic vesicle membrane] (R-HSA-2130423) AP2M1 [plasma membrane] (R-HSA-167585) AP2M1 [lysosomal membrane] (R-HSA-196144) AP2M1 [endolysosome membrane] (R-HSA-6784828) p-T156 AP2M1 [cytosol] (R-HSA-8856805)	0.556	3
UniProt:O95995 GAS8	1	GAS8 [cytosol] (R-HSA-5633057)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q08117 TLE5	1	AES [nucleoplasm] (R-HSA-4648963)	0.556	3
UniProt:Q8NAV1 PRPF38A	1	PRPF38A [nucleoplasm] (R-HSA-8867897)	0.534	2

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