SeMet is converted to AdoSeMet by MAT

Stable Identifier
R-HSA-2408551
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Methionine adenosyltransferases (MAT multimers) consisting of a S-adenosylmethionine synthase isoform type-1 (MAT1A) homodimer and a MAT1A: S-adenosylmethionine synthase isoform type-2 (MAT2A) heterodimer are responsible for the conversion of selenomethionine (SeMet) and ATP into Se-adenosylselenomethionine (AdoSeMet), orthophosphate (Pi), and diphosphate (PPi) (Kajander et al. 1990).

Literature References
PubMed ID Title Journal Year
2339986 Effects of selenomethionine on cell growth and on S-adenosylmethionine metabolism in cultured malignant cells

Akerman, KK, Pajula, RL, Kärenlampi, SO, Martikainen, H, Harvima, RJ, Kauppinen, L, Kajander, EO

Biochem. J. 1990
Participants
Participates
Catalyst Activity

selenomethionine adenosyltransferase activity of MAT1A multimers [cytosol]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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