Reactome | SGO1 [nucleoplasm]

SGO1 [nucleoplasm]

Stable Identifier

R-HSA-2468161

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

SGOL1, Shugoshin-like 1, hSgo1, Serologically defined breast cancer antigen NY-BR-85

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5FBB7 SGO1

Gene Names

SGO1, SGOL1

Chain

chain:1-561

Reference Genes

BioGPS Gene:151648 SGO1

COSMIC (genes):SGO1 SGO1

CTD Gene:151648 SGO1

dbSNP Gene:151648 SGO1

ENSEMBL:ENSG00000129810 SGO1

HGNC:25088 SGO1

KEGG:hsa:151648 SGO1

Monarch:151648 SGO1

NCBI Gene:151648 SGO1

OMIM:609168 SGO1

UCSC:Q5FBB7 SGO1

Reference Transcript

Other Identifiers

11730515_a_at

11753400_a_at

11760461_at

151648

1553690_PM_at

1553690_at

16951485

231938_PM_at

231938_at

2665573

2665574

2665577

2665578

2665579

2665580

2665581

2665582

2665583

2665584

2665585

2665586

2665588

2665592

2665594

2665595

2665596

58119_at

8085754

A_23_P29723

A_24_P225970

GE548715

GO:0000775

GO:0000776

GO:0000779

GO:0000922

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0007059

GO:0008608

GO:0010457

GO:0019900

GO:0022414

GO:0043226

GO:0045132

GO:0051301

GO:0071962

HMNXSV003048543

Hs.105153.0.S1_3p_at

Hs2.105153.1.S1_3p_at

ILMN_1730825

ILMN_2404906

PH_hs_0005847

PH_hs_0035519

TC03001227.hg

Participates

as an input of

CCNA:CDK1 phosphorylates SGO1 (Homo sapiens)

Other forms of this molecule

SGOL1 [cytosol]

p-S-SGO1 [nucleoplasm]

Inferred To

Sgo1 [nucleoplasm] (Mus musculus)

Sgo1 [nucleoplasm] (Rattus norvegicus)

SGO1 [nucleoplasm] (Bos taurus)

SGO1 [nucleoplasm] (Canis familiaris)

SGO1 [nucleoplasm] (Gallus gallus)

SGO1 [nucleoplasm] (Sus scrofa)

sgo1 [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_001012413.1, XP_011531675.1, XP_011531677.1, NP_001186184.1, NP_001186186.1, NP_001186185.1, NP_001186183.1, NP_612493.1, NP_001186180.1, NP_001186182.1, NP_001186181.1, XP_011531678.1, XP_011531679.1, NP_001012409.1, NP_001012410.1, NP_001012411.1, NP_001012412.1

OpenTargets

ENSG00000129810

ENSEMBL

ENSP00000389034, ENST00000419233, ENST00000421451, ENST00000442720, ENST00000443724, ENST00000417364, ENST00000263753, ENSP00000413070, ENST00000425061, ENST00000412997, ENSP00000306581, ENSP00000414960, ENSP00000411200, ENSP00000414129, ENST00000306698, ENST00000452020, ENSP00000394957, ENSP00000394613, ENSP00000410458, ENST00000437051, ENSP00000263753, ENSG00000129810, ENSP00000394625

HPA

ENSG00000129810-SGO1

GeneCards

SGO1

PRO

Q5FBB7

Pharos - Targets

Q5FBB7

Orphanet

SGO1

PDB

4A0I, 3Q6S, 3FGA, 7ZJS

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P67775 PPP2CA	4	PPP2CA [cytosol] (R-HSA-165971) PPP2CA [nucleoplasm] (R-HSA-165978) p-Y307-PPP2CA [cytosol] (R-HSA-8857939) MeL-PPP2CA [nucleoplasm] (R-HSA-8857791)	0.848	7
UniProt:Q8N3U4 STAG2	8	STAG2 [nucleoplasm] (R-HSA-163046) STAG2 [chromosome, centromeric region] (R-HSA-2466018) STAG2 [chromosome] (R-HSA-1638777) p-STAG2 [cytosol] (R-HSA-2484806) p-STAG2 [chromosome] (R-HSA-1638793) p-STAG2 [chromosome, centromeric region] (R-HSA-2466013) STAG2 [cytosol] (R-HSA-2484897) monoSUMO1-K-STAG2 [nucleoplasm] (R-HSA-3108187)	0.774	7
UniProt:P45973 CBX5	2	CBX5 [nucleoplasm] (R-HSA-994093) monoSUMO1-K84,K-CBX5 [nucleoplasm] (R-HSA-4615849)	0.744	4
UniProt:O60216 RAD21	14	RAD21 [nucleoplasm] (R-HSA-163042) RAD21 [chromosome, centromeric region] (R-HSA-2466012) RAD21 [chromosome] (R-HSA-1638775) p-S454-RAD21 [cytosol] (R-HSA-2500310) p-S454-RAD21 [chromosome] (R-HSA-2485164) p-S454-RAD21 [chromosome, centromeric region] (R-HSA-2485163) RAD21(1-172) [chromosome, centromeric region] (R-HSA-2467793) p-S454-RAD21(451-631) [chromosome, centromeric region] (R-HSA-2467790) RAD21(173-450) [chromosome, centromeric region] (R-HSA-2500296) RAD21(1-172) [cytosol] (R-HSA-2484901) RAD21(173-450) [cytosol] (R-HSA-2500308) p-S454-RAD21(451-631) [cytosol] (R-HSA-2500309) RAD21 [cytosol] (R-HSA-2484795) monoSUMO1-K-RAD21 [nucleoplasm] (R-HSA-3108183)	0.737	6
UniProt:Q14738 PPP2R5D	2	PPP2R5D [nucleoplasm] (R-HSA-3008956) PPP2R5D [cytosol] (R-HSA-3008950)	0.667	4
UniProt:Q15172 PPP2R5A	2	p-S28-PPP2R5A [cytosol] (R-HSA-9836658) PPP2R5A [cytosol] (R-HSA-196235)	0.655	5
UniProt:Q14683 SMC1A	4	SMC1A [nucleoplasm] (R-HSA-64561) SMC1A [chromosome, centromeric region] (R-HSA-2466015) SMC1A [chromosome] (R-HSA-1638774) SMC1A [cytosol] (R-HSA-2484798)	0.612	9
UniProt:P30153 PPP2R1A	2	PPP2R1A [cytosol] (R-HSA-165982) PPP2R1A [nucleoplasm] (R-HSA-165968)	0.569	4
UniProt:Q96FF9 CDCA5	6	p-S21,S75,T159-CDCA5 [chromosome, centromeric region] (R-HSA-2468269) p-S21,S75,T159-CDCA5 [cytosol] (R-HSA-2484804) p-S21,S75,T159-CDCA5 [chromosome] (R-HSA-2468266) CDCA5 [chromosome] (R-HSA-2468149) CDCA5 [chromosome, centromeric region] (R-HSA-2468260) CDCA5 [nucleoplasm] (R-HSA-2466357)	0.558	4
UniProt:P83916 CBX1	1	CBX1 [nucleoplasm] (R-HSA-9653629)	0.544	2
UniProt:Q53HL2 CDCA8	3	polySUMO2,3-CDCA8 [cytosol] (R-HSA-4655328) CDCA8 [nucleoplasm] (R-HSA-4655357) CDCA8 [cytosol] (R-HSA-375288)	0.509	3
UniProt:Q29RF7 PDS5A	4	PDS5A [cytosol] (R-HSA-2484799) PDS5A [chromosome] (R-HSA-2466360) PDS5A [chromosome, centromeric region] (R-HSA-2468259) PDS5A [nucleoplasm] (R-HSA-2468043)	0.462	4

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