Reactome | CATSPER1 [plasma membrane]

CATSPER1 [plasma membrane]

Stable Identifier

R-HSA-2534335

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Cation channel sperm-associated protein 1, CTSR1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8NEC5 CATSPER1

Gene Names

CATSPER1

Chain

chain:1-780

Reference Genes

BioGPS Gene:117144 CATSPER1

COSMIC (genes):CATSPER1 CATSPER1

CTD Gene:117144 CATSPER1

dbSNP Gene:117144 CATSPER1

ENSEMBL:ENSG00000175294 CATSPER1

HGNC:17116 CATSPER1

Monarch:117144 CATSPER1

NCBI Gene:117144 CATSPER1

OMIM:606389 CATSPER1

UCSC:Q8NEC5 CATSPER1

Reference Transcript

RefSeq:NM_053054.3 CATSPER1

Other Identifiers

117144

11731807_at

1552335_PM_at

1552335_at

16740659

3378044

3378045

3378047

3378048

3378049

3378050

3378052

3378053

3378054

3378055

3378056

3378057

3378058

3378059

3378060

3378061

3378062

3378063

3378064

3378065

3378066

3378067

7949553

87361_at

A_23_P52676

GE635968

GO:0005215

GO:0005216

GO:0005227

GO:0005245

GO:0005262

GO:0005515

GO:0005886

GO:0005929

GO:0006811

GO:0006816

GO:0007018

GO:0007283

GO:0016020

GO:0022414

GO:0030154

GO:0030317

GO:0031514

GO:0034702

GO:0036126

GO:0036128

GO:0043226

GO:0048870

GO:0055085

GO:0060296

GO:0070588

GO:0097228

HMNXSV003004881

HMNXSV003033160

Hs2.189105.1.S1_3p_s_at

ILMN_1789394

PH_hs_0027956

TC11001951.hg

Participates

as a member of

CatSper Channel Protein [plasma membrane] (Homo sapiens)

Inferred To

CATSPER1 [plasma membrane] (Bos taurus)

CATSPER1 [plasma membrane] (Canis familiaris)

CATSPER1 [plasma membrane] (Sus scrofa)

Catsper1 [plasma membrane] (Mus musculus)

Catsper1 [plasma membrane] (Rattus norvegicus)

Cross References

Guide to Pharmacology - Targets

388

ENSEMBL

ENST00000312106, ENSP00000309052

OpenTargets

ENSG00000175294

HPA

ENSG00000175294-CATSPER1

ZINC - Substances

CTSR1_HUMAN

ZINC target

Q8NEC5

PRO

Q8NEC5

Pharos - Targets

Q8NEC5

Orphanet

CATSPER1

HMDB Protein

HMDBP07637

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02652 APOA2	6	APOA2(24-100) [cytosol] (R-HSA-2395772) APOA2(24-100) [early endosome] (R-HSA-2569092) APOA2(24-100) [endoplasmic reticulum lumen] (R-HSA-174689) APOA2(24-100) [extracellular region] (R-HSA-174775) p-APOA2 [endoplasmic reticulum lumen] (R-HSA-8957014) APOA2 [endoplasmic reticulum lumen] (R-HSA-8956780)	0.781	7
UniProt:Q5VWX1 KHDRBS2	2	KHDRBS2 [nucleoplasm] (R-HSA-8849028) p-Y-KHDRBS2 [nucleoplasm] (R-HSA-8849031)	0.718	6
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.666	4
UniProt:P01137 TGFB1	7	TGFB1 [extracellular region] (R-HSA-170838) TGFB1(30-278) [extracellular region] (R-HSA-2395367) TGFB1(30-278) [Golgi lumen] (R-HSA-9736812) TGFB1 [Golgi lumen] (R-HSA-177108) TGFB1(30-390) [Golgi lumen] (R-HSA-114705) TGFB1 [plasma membrane] (R-HSA-5146781) TGFB1(30-278) [platelet alpha granule lumen] (R-HSA-65936)	0.556	3
UniProt:Q96IF1 AJUBA	3	AJUBA [nucleoplasm] (R-HSA-5687935) p-S-AJUBA [cytosol] (R-HSA-2574841) AJUBA [cytosol] (R-HSA-2564698)	0.556	3
UniProt:O43597 SPRY2	8	p-S112,S115-SPRY2 [cytosol] (R-HSA-1295619) SPRY2 [cytosol] (R-HSA-182949) SPRY2 [plasma membrane] (R-HSA-182924) p-S112,S121-SPRY2 [plasma membrane] (R-HSA-934595) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-934555) p-S111,S120-SPRY2 [cytosol] (R-HSA-1295590) p-Y55,Y227-SPRY2 [plasma membrane] (R-HSA-1295629) p-Y55-SPRY2 [cytosol] (R-HSA-182950)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:P08151 GLI1	9	ub-GLI1 [cytosol] (R-HSA-5635833) ub-pS-GLI1 [ciliary base] (R-HSA-5610514) pS-GLI1 [ciliary base] (R-HSA-5610497) GLI1 [cytosol] (R-HSA-445457) p-GLI1 [ciliary tip] (R-HSA-5635040) 2p-GLI1 [nucleoplasm] (R-HSA-5635057) p-GLI1 [nucleoplasm] (R-HSA-5635042) GLI1 [ciliary base] (R-HSA-5610357) GLI1 [ciliary tip] (R-HSA-5610360)	0.556	3
UniProt:Q9ULX6 AKAP8L	1	AKAP8L [nucleoplasm] (R-HSA-9821364)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:P19883 FST	1	FST [extracellular region] (R-HSA-2473211)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:O43559 FRS3	3	p-5Y-FRS3 [plasma membrane] (R-HSA-191475) FRS3 [plasma membrane] (R-HSA-191482) p-Y-FRS3 [plasma membrane] (R-HSA-9032427)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.556	3

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