Reactome | SARM-1 [cytosol]

SARM-1 [cytosol]

Stable Identifier

R-HSA-2559572

Type

Genes and Transcripts [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

sterile alpha and armadillo-motif-containing protein, SARM isoform 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q6SZW1-1 SARM1

Gene Names

SARM1, KIAA0524, SAMD2, SARM

Other Identifiers

11728111_at

11728112_s_at

11747556_s_at

11750238_a_at

16832461

213257_PM_at

213257_at

213259_PM_s_at

213259_s_at

23098

234060_3p_at

234060_PM_at

234060_at

3715559

3715560

3715561

3715562

3715563

3715569

3715570

3715571

3715572

3715573

3715574

3715575

3715576

3715577

3715578

3715579

3715580

3715581

3715584

3715585

3715586

3715587

3715588

3715589

3715593

3715595

3715596

3715597

41707_at

8005865

A_14_P114602

A_14_P121710

A_24_P267293

A_33_P3370763

GE53255

GE85199

GO:0002376

GO:0003824

GO:0003953

GO:0005515

GO:0005737

GO:0005739

GO:0005741

GO:0005829

GO:0005856

GO:0005874

GO:0007165

GO:0007399

GO:0009749

GO:0009986

GO:0015630

GO:0016787

GO:0019677

GO:0030154

GO:0030424

GO:0030425

GO:0031594

GO:0032991

GO:0034128

GO:0034330

GO:0035591

GO:0042802

GO:0042995

GO:0043226

GO:0043523

GO:0045087

GO:0045202

GO:0048678

GO:0048814

GO:0048856

GO:0050135

GO:0050877

GO:0055086

GO:0060090

GO:0061809

GO:0070585

GO:0098542

GO:0098978

GO:0099010

GO:0099243

GO:1905806

HMNXSV003009839

HMNXSV003011662

HMNXSV003024791

Hs.128759.0.A1_3p_a_at

Hs.128759.0.A2_3p_at

Hs.306884.0.S1_3p_at

Hs.306884.0.S1_3p_x_at

ILMN_1746265

PH_hs_0022674

TC17002141.hg

TC17002872.hg

p7261

p7262

Participates

as a component of

as an input of

Inferred To

SARM-1 [cytosol] (Caenorhabditis elegans)

SARM-1 [cytosol] (Danio rerio)

SARM-1 [cytosol] (Drosophila melanogaster)

SARM-1 [cytosol] (Mus musculus)

SARM-1 [cytosol] (Rattus norvegicus)

sarm1 [cytosol] (Xenopus tropicalis)

Ghost homologue of SARM-1 [cytosol] (Sus scrofa)

SARM1 [cytosol] (Bos taurus)

SARM1 [cytosol] (Canis familiaris)

Cross References

RefSeq

NP_055892.2

OpenTargets

ENSG00000004139

ENSEMBL

ENSP00000468032, ENST00000585482

HPA

ENSG00000004139-SARM1

PRO

Q6SZW1

Pharos - Targets

Q6SZW1

GlyGen

Q6SZW1

HMDB Protein

HMDBP12375

PDB

6O1B, 8GNJ, 8GNI, 6O0U, 6O0V, 7CM6, 6ZFX, 7QG0, 7KNQ, 7DJT, 6O0S, 7CM5, 6O0T, 7CM7, 6ZG1, 8D0H, 8D0J, 8D0I, 8D0C, 7NAI, 7NAG, 7NAH, 6WPK, 8GQ5, 8D0F, 8D0D, 8D0G, 8P2L, 8D0E, 6ZG0, 6QWV, 6O0R, 7ANW, 6O0Q, 7NAK, 7LD0, 7NAJ, 7NAL

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99836 MYD88	8	MyD88 R196C [cytosol] (R-HSA-5602329) MyD88 E52del [cytosol] (R-HSA-5602451) MyD88 L93P [cytosol] (R-HSA-5602612) MyD88 S34Y [cytosol] (R-HSA-5602521) MyD88 E65del [cytosol] (R-HSA-5602598) MYD88 [endosome membrane] (R-HSA-975123) MYD88 [plasma membrane] (R-HSA-937017) MYD88 [cytosol] (R-HSA-166059)	0.622	5
UniProt:Q86XR7 TICAM2	3	MyrG-p-S16-TICAM2 [plasma membrane] (R-HSA-166160) MyrG-p-S16-TICAM2 [secretory granule membrane] (R-HSA-6804964) MyrG-p-S16-TICAM2 [endosome membrane] (R-HSA-2201336)	0.592	2
UniProt:P56539 CAV3	1	CAV3 [plasma membrane] (R-HSA-1368135)	0.527	2
UniProt:P08173 CHRM4	1	CHRM4 [plasma membrane] (R-HSA-390693)	0.527	2
UniProt:Q8N4J0 CARNMT1	1	CARNMT1 [cytosol] (R-HSA-8876689)	0.527	3