activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane]

Stable Identifier
R-HSA-2562542
Type
Complex
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
21737330 cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms

Langlais, C, Geserick, P, Kellert, B, H├Ącker, G, Cain, K, Feoktistova, M, Hupe, M, MacFarlane, M, Leverkus, M, Dimitrova, DP

Mol. Cell 2011
16115877 Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation

Fitzgerald, KA, Cusson-Hermance, N, Khurana, S, Kelliher, MA, Lee, TH

J Biol Chem 2005
15814722 Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

Offermann, MK, Kaiser, WJ

J Immunol 2005
Participants
Participates
Inferred To
Cite Us!