p-S177-OPTN [nucleoplasm]

Stable Identifier
R-HSA-2562595
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-S177-Optineurin
Locations in the PathwayBrowser for interactor UniProt:Q9Y5Y5 PEX16
External Reference Information
External Reference
Gene Names
OPTN, FIP2, GLC1E, HIP7, HYPL, NRP
Chain
chain:1-577
Other Identifiers
0006020333
10133
11736020_a_at
11745271_x_at
11757341_s_at
16702547
202073_at
202074_s_at
3235730
3235731
3235732
3235737
3235738
3235739
3235742
3235743
3235744
3235746
3235749
3235750
3235752
3235755
3235757
3235759
3235761
3235762
3235767
3235768
3235769
3235771
41742_s_at
41743_i_at
41744_at
7926239
A_14_P127414
A_23_P1461
A_33_P3333317
GE82633
GE84788
GE85528
GO:0000086
GO:0000139
GO:0000278
GO:0001920
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005768
GO:0005773
GO:0005776
GO:0005794
GO:0005802
GO:0005829
GO:0006810
GO:0006914
GO:0006950
GO:0007005
GO:0007030
GO:0007049
GO:0007165
GO:0008022
GO:0008150
GO:0008219
GO:0009056
GO:0010508
GO:0015031
GO:0016032
GO:0016192
GO:0019899
GO:0030674
GO:0031267
GO:0031410
GO:0031593
GO:0034067
GO:0034613
GO:0034620
GO:0042802
GO:0043001
GO:0043122
GO:0043124
GO:0043167
GO:0043226
GO:0044403
GO:0045087
GO:0046872
GO:0048471
GO:0050829
GO:0055037
GO:0055038
GO:0061734
GO:0070530
GO:0090161
GO:1904417
HMNXSV003045739
Hs.278898.0.A2_3p_at
ILMN_1717586
ILMN_2381899
PH_hs_0024518
TC10000097.hg
g11415041_3p_s_at
Participates
This entity regulates
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-serine at 177
Coordinate
177
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Interactors (192)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15025 TNIP1  1 0.961 19
 UniProt:Q9Y3C0 WASC3      0.951 17
 UniProt:Q96CV9 OPTN  4 0.928 16
 UniProt:Q9UHD2 TBK1  5 0.863 15
 UniProt:P42858 HTT  1 0.824 15
 UniProt:Q8TC07 TBC1D15  1 0.805 9
 UniProt:Q9UJX2 CDC23  2 0.795 8
 UniProt:Q9HA65 TBC1D17  1 0.74 7
 UniProt:Q15038 DAZP2      0.718 6
 UniProt:Q9BS34 ZNF670  1 0.718 6
 UniProt:Q9NTZ6 RBM12      0.718 6
 UniProt:Q8IYU2 HACE1  1 0.693 15
 UniProt:Q96NC0 ZMAT2      0.675 4
 UniProt:Q8N448 LNX2      0.668 3
 UniProt:Q9BUY5 ZNF426  1 0.666 4
 UniProt:P61006 RAB8A  6 0.633 4
 UniProt:Q29122 MYO6      0.598 3
 UniProt:P54845-1 NRL      0.589 6
 UniProt:Q13501 SQSTM1  4 0.558 7
 UniProt:Q96EF9 ZHX1R      0.556 3
 UniProt:Q96LL4 CH048      0.556 3
 UniProt:O95340 PAPSS2  4 0.556 3
 UniProt:Q96MN9-2 Q96MN92      0.556 3
 UniProt:Q8N5A5-2 ZGPAT      0.556 3
 UniProt:P49450 CENPA  2 0.556 3
 IntAct:EBI-25910725 CCSB      0.556 3
 UniProt:Q8IV33 K0825      0.556 3
 UniProt:P23297 S100A1  1 0.556 3
 UniProt:Q8WXF7 ATLA1      0.556 3
 UniProt:Q8IZQ1-2 WDFY3      0.556 3
 UniProt:Q15797 SMAD1  4 0.556 3
 UniProt:Q9Y574-2 Q9Y5742      0.556 3
 UniProt:O15195-2 O151952      0.556 3
 UniProt:Q8WVJ2 NUDC2      0.556 3
 UniProt:P07384 CAPN1  4 0.556 3
 UniProt:Q96RQ9 IL4I1  1 0.556 3
 IntAct:EBI-25911021 CCSB      0.556 3
 UniProt:Q9HBL8 NMRAL1  1 0.556 3
 IntAct:EBI-25910851 CCSB      0.556 3
 UniProt:Q96PU8 QKI  2 0.556 3
 UniProt:O00203 AP3B1  4 0.556 3
 UniProt:Q71DI3 H3C15  57 0.556 3
 UniProt:I6L9D0 I6L9D0      0.556 3
 UniProt:P49459 UBE2A  3 0.556 3
 UniProt:Q5VZL5-4 ZMYM4      0.556 3
 UniProt:Q86VR2 RETR3      0.556 3
 UniProt:Q9BWG1 Q9BWG1      0.556 3
 UniProt:Q96G97-4 BSCL2      0.556 3
 UniProt:Q49A26-4 GLYR1      0.556 3
 UniProt:P52306-4 RAP1GDS1      0.556 3
 UniProt:Q6PCB6 ABHD17C  1 0.556 3
 UniProt:O75031 HSF2B      0.556 3
 UniProt:P40454 PTPA1      0.556 3
 UniProt:Q9NWS9-2 ZNF446      0.556 3
 UniProt:P04440 HLA-DPB1  9 0.556 3
 UniProt:Q14847-2 LASP1      0.556 3
 UniProt:Q9P2R7 SUCLA2  1 0.556 3
 UniProt:Q92185 ST8SIA1  1 0.556 3
 UniProt:Q6ZNA4-2 Q6ZNA42      0.556 3
 UniProt:Q0P5P2 CQ067      0.556 3
 UniProt:Q6NXG1-3 Q6NXG13      0.556 3
 UniProt:A2RRN7 A2RRN7      0.556 3
 UniProt:P78424 PO6F2      0.556 3
 UniProt:Q96B67 ARRD3      0.556 3
 UniProt:Q9C0D3 ZY11B      0.556 3
 UniProt:P61296-2 HAND2      0.556 3
 UniProt:Q13113 PDZ1I      0.556 3
 UniProt:Q5TZF3-1 Q5TZF31      0.556 3
 UniProt:Q9BUH6 PAXX      0.556 3
 UniProt:P08758 ANXA5  2 0.556 3
 UniProt:Q9ULX5 RN112      0.556 3
 UniProt:P15169 CPN1  1 0.556 3
 UniProt:P61026 RAB10  5 0.556 3
 UniProt:Q99942 RNF5  1 0.556 3
 IntAct:EBI-25911486 CCSB      0.556 3
 UniProt:O95671 ASML      0.556 3
 UniProt:Q8TBB0 THAP6      0.556 3
 UniProt:Q13702-2 Q137022      0.556 3
 UniProt:Q9UBT3 DKK4  2 0.556 3
 UniProt:Q9UDX5 MTFP1      0.556 3
 UniProt:Q3SX64 OD3L2      0.556 3
 UniProt:O60927 PP1RB      0.556 3
 UniProt:P55058-2 PLTP  1 0.556 3
 UniProt:P51116 FXR2      0.556 3
 UniProt:P28347-2 TEAD1      0.556 3
 UniProt:A1A4Y4 IRGM      0.556 3
 UniProt:Q8N1C3 GBRG1      0.556 3
 UniProt:P10276-2 RARA      0.556 3
 UniProt:Q6IE81-3 JADE1      0.556 3
 UniProt:Q9BYQ4 KRTAP9-2  1 0.556 3
 UniProt:Q13123 RED      0.556 3
 UniProt:Q9NSI6-4 BRWD1      0.556 3
 UniProt:Q9Y2X9 ZN281      0.556 3
 UniProt:P78410 BTN3A2  1 0.556 3
 UniProt:Q8IZS5 OFCC1      0.556 3
 UniProt:Q8IVL6-2 P3H3      0.556 3
 UniProt:Q53HV7-2 SMUG1      0.556 3
 UniProt:Q8IYE1 CCD13      0.556 3
 UniProt:Q9NY26 SLC39A1  1 0.556 3
 UniProt:O60711 LPXN      0.556 3
 UniProt:P51608 MECP2      0.556 3
 IntAct:EBI-25910368 CCSB      0.556 3
 UniProt:P18206-2 VCL      0.556 3
 UniProt:Q96LX8 ZNF597  1 0.556 3
 IntAct:EBI-25910801 CCSB      0.556 3
 UniProt:Q96HQ0 ZNF419  1 0.556 3
 UniProt:A2RU56 A2RU56      0.556 3
 UniProt:A4FUJ8 A4FUJ8      0.556 3
 UniProt:Q0P5N6 ARL16      0.556 3
 UniProt:P17021 ZNF17  1 0.556 3
 UniProt:Q9UQ53 MGAT4B  1 0.556 3
 UniProt:Q8N302-2 Q8N3022      0.556 3
 UniProt:Q6ZS81-2 Q6ZS812      0.556 3
 UniProt:Q8N205-2 SYNE4      0.556 3
 UniProt:P40325 HUA1      0.556 3
 UniProt:Q8N1Y9 YI025      0.556 3
 UniProt:Q86UD4 ZN329      0.556 3
 UniProt:Q2NKQ1-4 SGSM1      0.556 3
 UniProt:Q9P209 CEP72  1 0.556 3
 UniProt:O43829 ZBT14      0.556 3
 UniProt:Q9NR11-2 ZNF302      0.556 3
 UniProt:Q9Y5L3 ENTPD2  1 0.556 3
 UniProt:Q12904-2 AIMP1      0.556 6
 UniProt:Q13586 STIM1  1 0.556 3
 UniProt:Q8N0Y2-2 ZNF444      0.556 3
 UniProt:P26639 TARS1  1 0.556 3
 IntAct:EBI-25911396 CCSB      0.556 3
 UniProt:Q9UIR0-4 Q9UIR04      0.556 3
 UniProt:Q99732 LITAF      0.556 3
 UniProt:Q8TBE1 CNIH3  3 0.556 3
 UniProt:P01123  21 0.556 3
 UniProt:Q96G46 DUS3L      0.556 3
 UniProt:Q5VYS8-5 TUT7      0.556 3
 UniProt:P28566 HTR1E  1 0.556 3
 UniProt:Q96EY8 MMAB  4 0.556 3
 UniProt:Q9Y6Q9-5 NCOA3      0.556 3
 UniProt:Q08499-8 PDE4D      0.556 3
 UniProt:Q9BUL9 RPP25  1 0.556 3
 UniProt:P24666-2 P246662      0.556 3
 UniProt:Q8TDB4 HUMMR      0.556 3
 UniProt:Q6XD76 ASCL4      0.556 3
 UniProt:P40302  1 0.556 3
 UniProt:P17029 ZKSCAN1  1 0.556 3
 UniProt:P54274-2 TERF1      0.556 3
 UniProt:P10074 TZAP      0.556 3
 IntAct:EBI-25910474 CCSB      0.556 3
 UniProt:Q86TI2-2 Q86TI22      0.556 3
 UniProt:P50749 RASF2      0.556 3
 UniProt:O95872 GPAN1      0.556 3
 UniProt:Q96GM5 SMARCD1  1 0.556 3
 UniProt:Q02556 IRF8  1 0.556 3
 UniProt:Q32M92-2 Q32M922      0.556 3
 UniProt:Q3KNW7 Q3KNW7      0.556 3
 UniProt:P35998 PSMC2  5 0.556 3
 UniProt:Q8TD17 ZNF398  1 0.556 3
 IntAct:EBI-25851697 CCSB      0.556 3
 UniProt:Q496A3 SPAS1      0.556 3
 UniProt:Q96EZ4 MYEOV      0.556 3
 UniProt:Q8IXS6 PALM2      0.556 3
 UniProt:A0A1C3PI11 A0A1C3PI11      0.556 3
 UniProt:Q9Y221 NIP7  1 0.556 3
 UniProt:Q969S8 HDAC10  1 0.556 3
 UniProt:O00560 SDCBP  3 0.556 3
 UniProt:Q9H6R3 ACSS3  1 0.556 3
 UniProt:O15392 BIRC5  3 0.556 3
 UniProt:Q9NRA0 SPHK2  1 0.556 3
 UniProt:Q13573 SNW1  1 0.556 3
 UniProt:Q9Y5Y5 PEX16  2 0.556 3
 UniProt:P52888 THOP1  1 0.556 3
 UniProt:P51582 P2RY4  1 0.556 3
 UniProt:P23528 CFL1  3 0.556 3
 UniProt:Q9BUH8 BEGAIN  1 0.556 3
 UniProt:Q9NRD5 PICK1  2 0.556 3
 UniProt:Q9BYZ2 LDHAL6B  1 0.556 3
 UniProt:Q9BV73 CEP250  1 0.556 3
 UniProt:Q9BUB5 MKNK1  1 0.556 3
 UniProt:O75604 USP2  2 0.556 3
 UniProt:Q96QE2 SLC2A13  1 0.556 3
 UniProt:P07225 PROS1  8 0.556 3
 UniProt:Q9NWF9 RNF216  1 0.556 3
 UniProt:Q14894 CRYM  1 0.556 3
 UniProt:Q6YHU6 THADA  1 0.556 3
 UniProt:P61007  5 0.527 2
 UniProt:O75923 DYSF  1 0.505 3
 UniProt:Q00013 MPP1  1 0.499 2
 UniProt:Q99IB8-PRO_0000045599      0.488 3
 UniProt:Q13023 AKAP6      0.454 2
 UniProt:Q9UNH7 SNX6      0.454 2
 UniProt:Q8WZ42 TTN  2 0.454 2
 UniProt:Q14BN4 SLMAP      0.454 2
 UniProt:Q03001 DST  1 0.454 2
 UniProt:P04275 VWF  3 0.454 2
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