Reactome | DLGAP5 [cytosol]

DLGAP5 [cytosol]

Stable Identifier

R-HSA-264452

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

HURP

Locations in the PathwayBrowser for interactor UniProt:P68363 TUBA1B

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External Reference Information

External Reference

UniProt:Q15398 DLGAP5

Gene Names

DLGAP5, DLG7, KIAA0008

Chain

chain:1-846

Reference Genes

BioGPS Gene:9787 DLGAP5

COSMIC (genes):DLGAP5 DLGAP5

CTD Gene:9787 DLGAP5

dbSNP Gene:9787 DLGAP5

ENSEMBL:ENSG00000126787 DLGAP5

HGNC:16864 DLGAP5

KEGG:hsa:9787 DLGAP5

Monarch:9787 DLGAP5

NCBI Gene:9787 DLGAP5

OMIM:617859 DLGAP5

UCSC:Q15398 DLGAP5

Reference Transcript

Other Identifiers

11722367_a_at

11744793_x_at

16793225

203764_PM_at

203764_at

3565671

3565672

3565675

3565677

3565678

3565679

3565680

3565681

3565683

3565684

3565685

3565686

3565687

3565688

3565689

3565690

3565691

3565692

3565693

3565694

3565695

3565696

3565697

3565698

3565699

3565701

3565702

37231_at

7979307

9787

A_23_P88331

D13633_at

GE57064

GO:0005515

GO:0005634

GO:0005737

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0007010

GO:0007018

GO:0007052

GO:0007059

GO:0007079

GO:0007346

GO:0008017

GO:0008092

GO:0023052

GO:0031616

GO:0043226

GO:0045842

GO:0051382

GO:0051642

GO:0065003

GO:0072686

HMNXSV003027914

ILMN_1749829

PH_hs_0004483

TC14001155.hg

g7661851_3p_at

Participates

as an output of

DLGAP5 gene transcription is stimulated by NOTCH3 (Homo sapiens)

Cross References

ENSEMBL

ENST00000395425, ENSP00000378815, ENST00000247191, ENSP00000247191

OpenTargets

ENSG00000126787

HPA

ENSG00000126787-DLGAP5

PRO

Q15398

Pharos - Targets

Q15398

GlyGen

Q15398

PDB

7ZX4

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14974 KPNB1	5	KPNB1 [cytosol] (R-HSA-180733) KPNB1 [nucleoplasm] (R-HSA-180714) KPNB1 [specific granule lumen] (R-HSA-6799646) KPNB1 [extracellular region] (R-HSA-6806306) KPNB1 [ficolin-1-rich granule lumen] (R-HSA-6800978)	0.725	5
UniProt:Q00610 CLTC	10	CLTC [trans-Golgi network membrane] (R-HSA-5333703) CLTC [cytosol] (R-HSA-8856820) CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-ALK(1058-1620) fusion [cytosol] (R-HSA-9710852) CLTC(2-1634)insV-p-7Y-ALK(1059-1620) fusion [cytosol] (R-HSA-9710854) CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9710835) CLTC(2-1634)insV-ALK(1059-1620) fusion [cytosol] (R-HSA-9710853) CLTC [endolysosome membrane] (R-HSA-8870827) CLTC [clathrin-coated endocytic vesicle membrane] (R-HSA-5138450) CLTC [lysosomal membrane] (R-HSA-2980660) CLTC [plasma membrane] (R-HSA-2980668)	0.645	4
UniProt:P68363 TUBA1B	9	TUBA1B [cytosol] (R-HSA-191691) TUBA1B [axonemal microtubule] (R-HSA-5610434) TUBA1B(1-450) [cytosol] (R-HSA-8955581) Polyglutamyl-TUBA1B [cytosol] (R-HSA-8867435) L-isoglutamyl polyglycyl-TUBA1B [cytosol] (R-HSA-8867436) TUBA1B unfolded [cytosol] (R-HSA-392781) TUBA1B folding intermediate [cytosol] (R-HSA-392797) Ac K40 TUBA1B [axonemal microtubule] (R-HSA-5624854) AcK-TUBA1B [cytosol] (R-HSA-5618285)	0.643	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:P68371 TUBB4B	8	TUBB4B folding intermediate [cytosol] (R-HSA-392788) TUBB4B unfolded [cytosol] (R-HSA-392779) Polyglycyl-TUBB4B [cytosol] (R-HSA-8867452) Polyglutamyl-TUBB4B [cytosol] (R-HSA-8867427) TUBB4B [axonemal microtubule] (R-HSA-5610441) TUBB4B [extracellular region] (R-HSA-6806178) TUBB4B [azurophil granule lumen] (R-HSA-6799347) TUBB4B [cytosol] (R-HSA-191702)	0.527	2
UniProt:Q13509 TUBB3	6	TUBB3 [cytosol] (R-HSA-190532) TUBB3 [axonemal microtubule] (R-HSA-5610436) Polyglutamyl-TUBB3 [cytosol] (R-HSA-8867464) Polyglycyl-TUBB3 [cytosol] (R-HSA-8867372) TUBB3 unfolded [cytosol] (R-HSA-392770) TUBB3 folding intermediate [cytosol] (R-HSA-392806)	0.527	3
UniProt:P62826 RAN	2	RAN [cytosol] (R-HSA-165540) RAN [nucleoplasm] (R-HSA-165528)	0.527	3
UniProt:O14524 NEMP1			0.527	2
UniProt:P68366 TUBA4A	9	TUBA4A [cytosol] (R-HSA-191694) TUBA4A [axonemal microtubule] (R-HSA-5610443) TUBA4A [extracellular region] (R-HSA-350734) Polyglutamyl-TUBA4A [cytosol] (R-HSA-8867386) L-isoglutamyl polyglycyl-TUBA4A [cytosol] (R-HSA-8867378) TUBA4A unfolded [cytosol] (R-HSA-392771) TUBA4A folding intermediate [cytosol] (R-HSA-392800) Ac K40 TUBA4A [axonemal microtubule] (R-HSA-5624859) AcK-TUBA4A [cytosol] (R-HSA-5618318)	0.527	2
UniProt:P61769 B2M	11	B2M(21-119) [plasma membrane] (R-HSA-167743) B2M(21-119) [endoplasmic reticulum lumen] (R-HSA-983063) B2M(21-119) [specific granule lumen] (R-HSA-6806144) B2M(21-119) [extracellular region] (R-HSA-1302721) B2M(21-119) [tertiary granule lumen] (R-HSA-6800179) B2M(21-119) [Golgi membrane] (R-HSA-983403) B2M(21-119) [ER to Golgi transport vesicle membrane] (R-HSA-983378) B2M(21-119) [early endosome lumen] (R-HSA-1236827) B2M(21-119) [recycling endosome membrane] (R-HSA-8863880) B2M(21-119) [phagocytic vesicle membrane] (R-HSA-1236891) B2M(21-119) [early endosome membrane] (R-HSA-182298)	0.527	3

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