Reactome | EXOC2 [plasma membrane]

EXOC2 [plasma membrane]

Stable Identifier

R-HSA-264887

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser for interactor UniProt:P27930 IL1R2

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External Reference Information

External Reference

UniProt:Q96KP1 EXOC2

Gene Names

EXOC2, SEC5, SEC5L1

Chain

chain:1-924

Reference Genes

BioGPS Gene:55770 EXOC2

COSMIC (genes):EXOC2 EXOC2

CTD Gene:55770 EXOC2

dbSNP Gene:55770 EXOC2

ENSEMBL:ENSG00000112685 EXOC2

ENSEMBL_homo_sapiens_GENE:ENSG00000112685.14 EXOC2

HGNC:24968 EXOC2

KEGG Gene (Homo sapiens):55770 EXOC2

Monarch:55770 EXOC2

NCBI Gene:55770 EXOC2

OMIM:615329 EXOC2

UCSC:Q96KP1 EXOC2

Reference Transcript

Other Identifiers

11722267_s_at

11750944_a_at

11755556_a_at

17014963

219349_PM_s_at

219349_s_at

226270_PM_at

226270_at

2938217

2938218

2938219

2938220

2938221

2938222

2938223

2938225

2938227

2938229

2938233

2938253

2938263

2938264

2938265

2938266

2938267

2938269

2938270

2938271

2938272

2938274

2938275

2938284

2938285

2938287

2938288

2938289

2938293

2938295

2938296

2938302

2938303

2938304

2938305

2938319

2938320

55770

57344_at

57812_at

58333_at

8123524

A_23_P214354

GE55949

GO:0000145

GO:0000278

GO:0000281

GO:0000910

GO:0005515

GO:0005829

GO:0005886

GO:0006887

GO:0006893

GO:0006904

GO:0015031

GO:0016020

GO:0016192

GO:0019901

GO:0031267

GO:0061024

GO:0090148

GO:0090522

GO:0090543

GO:2000535

HMNXSV003054090

Hs.16580.1.S1_3p_at

ILMN_1731180

ILMN_2065783

PH_hs_0025526

TC06001207.hg

g8922829_3p_a_at

Participates

as a component of

Exocyst Complex [plasma membrane] (Homo sapiens)

as an input of

Exocyst complex formation (Homo sapiens)

Other forms of this molecule

EXOC2 [cytosol]

Inferred To

Sec5 [plasma membrane] (Drosophila melanogaster)

EXOC2 [plasma membrane] (Bos taurus)

EXOC2 [plasma membrane] (Canis familiaris)

EXOC2 [plasma membrane] (Gallus gallus)

sec-5 [plasma membrane] (Caenorhabditis elegans)

SEC5 [plasma membrane] (Saccharomyces cerevisiae)

exoc2 [plasma membrane] (Dictyostelium discoideum)

exoc2 [plasma membrane] (Xenopus tropicalis)

sec5 [plasma membrane] (Schizosaccharomyces pombe)

Exoc2 [plasma membrane] (Mus musculus)

Exoc2 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_060773.3, XP_016866511.1, XP_016866510.1, XP_016866508.1, XP_016866509.1, XP_016866507.1, XP_016866513.1, XP_016866512.1

OpenTargets

ENSG00000112685

GeneCards

Q96KP1

HPA

ENSG00000112685-EXOC2

Ensembl

ENSP00000230449, ENSG00000112685, ENST00000230449

PRO

Q96KP1

Pharos - Targets

Q96KP1

HMDB Protein

HMDBP08385

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NV70 EXOC1	2	EXOC1 [plasma membrane] (R-HSA-2872284) EXOC1 [cytosol] (R-HSA-5623375)	0.845	8
UniProt:Q8TAG9 EXOC6	2	EXOC6 [plasma membrane] (R-HSA-265041) EXOC6 [cytosol] (R-HSA-5623384)	0.725	5
UniProt:O60645 EXOC3	2	EXOC3 [secretory granule membrane] (R-HSA-2872286) EXOC3 [cytosol] (R-HSA-5623379)	0.725	6
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.638	4
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.638	4
UniProt:Q9Y2D4 EXC6B			0.638	3
UniProt:P27930 IL1R2	1	IL1R2 [plasma membrane] (R-HSA-197598)	0.527	4
UniProt:P35414 APLNR	1	APLNR [plasma membrane] (R-HSA-374259)	0.527	2
UniProt:P20309 CHRM3	1	CHRM3 [plasma membrane] (R-HSA-399994)	0.527	2
UniProt:P11234 RALB	1	RALB [cytosol] (R-HSA-171015)	0.508	3
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.508	2

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