Reactome | STT3B [endoplasmic reticulum membrane]

STT3B [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-264930

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Locations in the PathwayBrowser for interactor UniProt:Q14165 MLEC

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External Reference Information

External Reference

UniProt:Q8TCJ2 STT3B

Gene Names

STT3B, SIMP

Chain

initiator methionine:, chain:2-826

Reference Genes

BioGPS Gene:201595 STT3B

COSMIC (genes):STT3B STT3B

CTD Gene:201595 STT3B

dbSNP Gene:201595 STT3B

ENSEMBL:ENSG00000163527 STT3B

HGNC:30611 STT3B

KEGG:hsa:201595 STT3B

Monarch:201595 STT3B

NCBI Gene:201595 STT3B

OMIM:608605 STT3B

UCSC:Q8TCJ2 STT3B

Reference Transcript

RefSeq:NM_178862.2 STT3B

Other Identifiers

11754645_x_at

11756482_x_at

11756951_x_at

11759034_at

11759035_x_at

11759036_at

11764246_s_at

16938583

201595

224700_PM_at

224700_at

2615605

2615606

2615607

2615608

2615609

2615610

2615611

2615617

2615621

2615622

2615624

2615626

2615630

2615631

2615632

2615634

2615638

2615639

2615641

2615642

2615643

2615644

2615645

2615646

2615648

2615649

2615653

2615654

2615655

2615656

2615657

65745_s_at

66666_at

8078360

A_14_P101962

A_23_P434473

A_24_P341958

A_32_P1055

GE558161

GO:0003824

GO:0004576

GO:0004579

GO:0005515

GO:0005783

GO:0005789

GO:0006486

GO:0006487

GO:0006516

GO:0006986

GO:0008250

GO:0016020

GO:0016740

GO:0016757

GO:0018279

GO:0030163

GO:0032991

GO:0034998

GO:0036503

GO:0043226

GO:0043686

GO:0043687

GO:0046872

GO:1901135

HMNXSV003037431

Hs.183454.0.A1_3p_at

ILMN_2194448

PH_hs_0022753

TC03000152.hg

Participates

as an output of

MITF-M-dependent STT3B gene expression (Homo sapiens)

as a component of

OST-B Subcomplex II [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_849193.1

ENSEMBL

ENST00000295770, ENSP00000295770, ENSG00000163527

OpenTargets

ENSG00000163527

IntEnz

2.4.99.18

GeneCards

STT3B

HPA

ENSG00000163527-STT3B

PRO

Q8TCJ2

Pharos - Targets

Q8TCJ2

GlyGen

Q8TCJ2

HMDB Protein

HMDBP07257

PDB

6S7T

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04843 RPN1	1	RPN1 [endoplasmic reticulum membrane] (R-HSA-264994)	0.688	4
UniProt:Q14165 MLEC	3	MLEC [endoplasmic reticulum membrane] (R-HSA-901082) MLEC [plasma membrane] (R-HSA-6806292) MLEC [specific granule membrane] (R-HSA-6799618)	0.657	3
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.644	5
UniProt:Q96GX1 TCTN2	1	TCTN2 [ciliary membrane] (R-HSA-5626661)	0.619	4
UniProt:Q0VD86 INCA1			0.556	3
UniProt:P61803 DAD1	1	DAD1 [endoplasmic reticulum membrane] (R-HSA-265089)	0.528	2
UniProt:Q9P0L0 VAPA	4	VAPA [azurophil granule membrane] (R-HSA-6799364) VAPA [plasma membrane] (R-HSA-6806269) VAPA [endoplasmic reticulum membrane] (R-HSA-429677) VAPA [cytosol] (R-HSA-9609920)	0.527	3
UniProt:Q13454 TUSC3	2	TUSC3(1-348) [plasma membrane] (R-HSA-5339529) TUSC3 [endoplasmic reticulum membrane] (R-HSA-9932255)	0.527	2
UniProt:P04844 RPN2	1	RPN2 [endoplasmic reticulum membrane] (R-HSA-264937)	0.527	3