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EXOC6 [plasma membrane]
Stable Identifier
R-HSA-265041
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser for interactor UniProt:P49146 NPY2R
Expand all
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Insulin processing (Homo sapiens)
Exocyst complex formation (Homo sapiens)
EXOC6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TAG9 EXOC6
Gene Names
EXOC6, SEC15A, SEC15L, SEC15L1
Chain
chain:1-804
Reference Genes
BioGPS Gene:54536 EXOC6
COSMIC (genes):EXOC6 EXOC6
CTD Gene:54536 EXOC6
dbSNP Gene:54536 EXOC6
ENSEMBL:ENSG00000138190 EXOC6
ENSEMBL_homo_sapiens_GENE:ENSG00000138190.17 EXOC6
HGNC:23196 EXOC6
KEGG Gene (Homo sapiens):54536 EXOC6
Monarch:54536 EXOC6
NCBI Gene:54536 EXOC6
OMIM:609672 EXOC6
UCSC:Q8TAG9 EXOC6
Reference Transcript
RefSeq:NM_001013848.3 EXOC6
RefSeq:NM_001319200.1 EXOC6
RefSeq:NM_001319194.1 EXOC6
RefSeq:NM_019053.5 EXOC6
RefSeq:NM_001319195.1 EXOC6
RefSeq:XM_017016345.1 EXOC6
Other Identifiers
11723221_a_at
11755493_a_at
16707503
226259_PM_at
226259_at
233924_PM_s_at
233924_s_at
3258257
3258261
3258262
3258271
3258283
3258284
3258285
3258286
3258288
3258290
3258292
3258295
3258298
3258301
3258302
3258303
3258304
3258306
3258307
3258308
3258309
3258311
3258318
3258319
3258320
3258328
3258338
3258341
3258342
3258355
3258356
49287_at
54536
59310_at
7929288
A_14_P139287
A_23_P169576
A_32_P58280
GE56714
GO:0000145
GO:0000278
GO:0000281
GO:0000910
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0006886
GO:0006887
GO:0006893
GO:0006904
GO:0015031
GO:0016192
GO:0030426
GO:0042995
GO:0048471
GO:0061024
GO:0090148
GO:0090522
GO:0090543
HMNXSV003000060
HMNXSV003056933
Hs.110454.0.S1_3p_at
Hs.110454.1.S1_3p_a_at
ILMN_1651628
ILMN_1667686
ILMN_1679687
PH_hs_0023364
TC10000661.hg
Participates
as a component of
Exocyst Complex [plasma membrane] (Homo sapiens)
as an input of
Exocyst complex formation (Homo sapiens)
Other forms of this molecule
EXOC6 [cytosol]
Inferred To
Sec15 [plasma membrane]
(Drosophila melanogaster)
EXOC6 [plasma membrane]
(Bos taurus)
EXOC6 [plasma membrane]
(Canis familiaris)
EXOC6 [plasma membrane]
(Gallus gallus)
Exoc6 [plasma membrane]
(Mus musculus)
Exoc6 [plasma membrane]
(Rattus norvegicus)
sec-15 [plasma membrane]
(Caenorhabditis elegans)
SEC15 [plasma membrane]
(Saccharomyces cerevisiae)
sec15 [plasma membrane]
(Schizosaccharomyces pombe)
exoc6 [plasma membrane]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001306124.1
,
NP_001306129.1
,
NP_001013870.1
,
NP_001306123.1
,
XP_016871834.1
,
NP_061926.3
OpenTargets
ENSG00000138190
HPA
ENSG00000138190-EXOC6
GeneCards
Q8TAG9
Ensembl
ENST00000672817
,
ENSG00000138190
,
ENST00000371552
,
ENSP00000500529
,
ENSP00000360607
,
ENSP00000500468
,
ENST00000260762
,
ENSP00000260762
,
ENST00000671701
PRO
Q8TAG9
Pharos - Targets
Q8TAG9
Interactors (23)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00471 EXOC5
2
EXOC5 [cytosol]
(R-HSA-265045)
EXOC5 [cytosol]
(R-HSA-5623383)
0.841
9
UniProt:Q96A65 EXOC4
2
EXOC4 [plasma membrane]
(R-HSA-264989)
EXOC4 [cytosol]
(R-HSA-5623381)
0.789
7
UniProt:Q8IYI6 EXOC8
2
EXOC8 [plasma membrane]
(R-HSA-264948)
EXOC8 [cytosol]
(R-HSA-5623388)
0.725
6
UniProt:Q96KP1 EXOC2
2
EXOC2 [plasma membrane]
(R-HSA-264887)
EXOC2 [cytosol]
(R-HSA-5623376)
0.725
5
UniProt:O60645 EXOC3
2
EXOC3 [secretory granule membrane]
(R-HSA-2872286)
EXOC3 [cytosol]
(R-HSA-5623379)
0.638
4
UniProt:Q9NV70 EXOC1
2
EXOC1 [plasma membrane]
(R-HSA-2872284)
EXOC1 [cytosol]
(R-HSA-5623375)
0.638
4
UniProt:Q9UPT5 EXOC7
2
EXOC7 [plasma membrane]
(R-HSA-2872288)
EXOC7 [cytosol]
(R-HSA-5623386)
0.638
5
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:Q53GS7 GLE1
1
GLE1 [nucleoplasm]
(R-HSA-8932905)
0.556
3
UniProt:Q9H410 DSN1
3
DSN1 [cytosol]
(R-HSA-375308)
DSN1 [azurophil granule lumen]
(R-HSA-6799218)
DSN1 [extracellular region]
(R-HSA-6806228)
0.527
3
UniProt:P32970 CD70
1
CD70 [plasma membrane]
(R-HSA-5667139)
0.527
2
UniProt:O75558 STX11
0.527
2
UniProt:P49146 NPY2R
1
NPY2R [plasma membrane]
(R-HSA-388905)
0.527
2
UniProt:Q8N7X8 SIGL1
0.527
2
UniProt:P62834 RAP1A
4
RAP1A [plasma membrane]
(R-HSA-354118)
RAP1A [endosome membrane]
(R-HSA-190053)
RAP1A [cytosol]
(R-HSA-169884)
RAP1A [specific granule membrane]
(R-HSA-6806137)
0.527
2
UniProt:Q5VIR6 VPS53
1
VPS53 [trans-Golgi network membrane]
(R-HSA-6811031)
0.527
2
UniProt:P27930 IL1R2
1
IL1R2 [plasma membrane]
(R-HSA-197598)
0.527
4
UniProt:P08173 CHRM4
1
CHRM4 [plasma membrane]
(R-HSA-390693)
0.527
2
UniProt:P35414 APLNR
1
APLNR [plasma membrane]
(R-HSA-374259)
0.527
2
UniProt:P61006 RAB8A
6
GGC-RAB8A [cytoplasmic vesicle membrane]
(R-HSA-1445093)
RAB8A [recycling endosome membrane]
(R-HSA-8854145)
GGC-RAB8A [trans-Golgi network membrane]
(R-HSA-8876082)
GGC-RAB8A [cytosol]
(R-HSA-8874063)
RAB8A [Golgi membrane]
(R-HSA-2562535)
RAB8A [cytosol]
(R-HSA-5623399)
0.508
2
UniProt:Q9Y2D4 EXC6B
0.508
2
UniProt:Q16891 IMMT
1
IMMT (MIC60) [mitochondrial inner membrane]
(R-HSA-8949569)
0.508
2
UniProt:P0DTD1-PRO_0000449633 REP
0.488
2
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