Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
3,4-Hyp 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
Stable Identifier
R-HSA-2682376
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
COL4A6, CO4A6_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Collagen formation (Homo sapiens)
Assembly of collagen fibrils and other multimeric structures (Homo sapiens)
Crosslinking of collagen fibrils (Homo sapiens)
Collagen type IV sulfilimine cross-linking by peroxidasin (Homo sapiens)
Collagen type IV networks with sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfilimine-containing collagen type IV alpha1.alpha2.alpha5.alpha6 network [extracellular region] (Homo sapiens)
Collagen type IV alpha1.alpha2.alpha5.alpha6 tropocollagens with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) with or without sulfilimine cross-links [extracellular region] (Homo sapiens)
Sulfiliminyl tropocollagen alpha-5(IV).alpha-5(IV).alpha-6(IV) [extracellular region] (Homo sapiens)
Sulfiliminyl collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
3,4-Hyp 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14031 COL4A6
Gene Names
COL4A6
Chain
signal peptide:1-22, chain:23-1691
Reference Genes
BioGPS Gene:1288 COL4A6
COSMIC (genes):COL4A6 COL4A6
CTD Gene:1288 COL4A6
dbSNP Gene:1288 COL4A6
ENSEMBL:ENSG00000197565 COL4A6
ENSEMBL_homo_sapiens_GENE:ENSG00000197565.17 COL4A6
HGNC:2208 COL4A6
KEGG Gene (Homo sapiens):1288 COL4A6
Monarch:1288 COL4A6
NCBI Gene:1288 COL4A6
OMIM:303631 COL4A6
UCSC:Q14031 COL4A6
Reference Transcript
RefSeq:NM_033641.3 COL4A6
RefSeq:NM_001847.3 COL4A6
RefSeq:NM_001287760.1 COL4A6
Other Identifiers
11725910_a_at
11741797_a_at
11750015_a_at
11751887_a_at
11751888_x_at
11751893_a_at
1288
17113195
211473_PM_s_at
211473_s_at
213992_PM_at
213992_at
39939_at
4017539
4017540
4017541
4017542
4017543
4017544
4017545
4017547
4017548
4017549
4017550
4017551
4017552
4017553
4017556
4017557
4017558
4017560
4017561
4017563
4017564
4017565
4017567
4017568
4017569
4017570
4017571
4017577
4017578
4017579
4017580
4017581
4017582
4017583
4017584
4017586
4017589
4017592
4017593
4017594
4017595
4017596
4017597
4017598
4017599
4017601
4017603
4017605
4017607
4017608
4017609
4017611
4017613
4017614
4017615
4017617
4017620
4017625
4017626
4017632
4017633
4017634
4017661
4017677
4017678
4017679
779_at
8174389
A_23_P217379
D21337_at
GE83658
GE88012
GO:0005198
GO:0005201
GO:0005515
GO:0005576
GO:0005581
GO:0005587
GO:0005604
GO:0005615
GO:0005783
GO:0005788
GO:0007155
GO:0023052
GO:0030020
GO:0030198
GO:0030312
GO:0031012
GO:0038063
GO:0043226
GO:0062023
GO:0071230
HMNXSV003029591
HMNXSV003040585
Hs.408.2.S1_3p_at
ILMN_1675857
ILMN_1811289
ILMN_1813021
PH_hs_0000049
TC0X001267.hg
g496977_3p_a_at
Participates
as a member of
Sulfiliminyl collagen alpha-6(IV) chains [extracellular region] (Homo sapiens)
Other forms of this molecule
3x4Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-GalHyl-COL4A6 [endoplasmic reticulum lumen]
GlcGalHyl-COL4A6 [endoplasmic reticulum lumen]
GalHyl-COL4A6 [endoplasmic reticulum lumen]
COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen]
3x4Hyp-3Hyp-5Hyl-COL4A6 [endoplasmic reticulum lumen]
5Hyl-COL4A6 [endoplasmic reticulum lumen]
5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
4-Hyp 5-sulfiliminyl collagen alpha-6(IV) chain [extracellular region]
GlcGalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-COL4A6(?-1691) [extracellular region]
3x4Hyp-GalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-5Hyl-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A6(23-?) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6(23-?) [extracellular region]
COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6(?-1691) [extracellular region]
5Hyl-COL4A6(23-?) [extracellular region]
GalHyl-COL4A6(?-1691) [extracellular region]
5Hyl-COL4A6(?-1691) [extracellular region]
GlcGalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-GalHyl-COL4A6(23-?) [extracellular region]
GalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6(?-1691) [extracellular region]
COL4A6(23-?) [extracellular region]
3x4Hyp-5Hyl-COL4A6(?-1691) [extracellular region]
3x4Hyp-3Hyp-COL4A6(23-?) [extracellular region]
3x4Hyp-COL4A6(23-?) [extracellular region]
3x4Hyp-3Hyp-COL4A6 [extracellular region]
5Hyl-COL4A6 [extracellular region]
3x4Hyp-3Hyp-GlcGalHyl-COL4A6 [extracellular region]
3x4Hyp-COL4A6 [extracellular region]
3x4Hyp-3Hyp-5Hyl-COL4A6 [extracellular region]
3x4Hyp-GalHyl-COL4A6 [extracellular region]
GalHyl-COL4A6 [extracellular region]
3x4Hyp-3Hyp-GalHyl-COL4A6 [extracellular region]
3x4Hyp-GlcGalHyl-COL4A6 [extracellular region]
3x4Hyp-5Hyl-COL4A6 [extracellular region]
COL4A6 [extracellular region]
GlcGalHyl-COL4A6 [extracellular region]
Inferred To
COL4A6 [extracellular region]
(Bos taurus)
COL4A6 [extracellular region]
(Canis familiaris)
COL4A6 [extracellular region]
(Sus scrofa)
Col4a6 [extracellular region]
(Mus musculus)
Col4a6 [extracellular region]
(Rattus norvegicus)
Modified Residues
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,4R)-4-hydroxyproline at unknown position
PsiMod Name
(2S,4R)-4-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 4-hydroxy-L-proline
Name
(2S,3S)-3-hydroxyproline at unknown position
PsiMod Name
(2S,3S)-3-hydroxyproline
PsiMod Definition
A protein modification that effectively converts an L-proline residue to 3-hydroxy-L-proline.
Name
(2S,5R)-5-hydroxylysine (sulfilimine bond) at unknown position
Modification
sulfilimine bond
PsiMod Name
(2S,5R)-5-hydroxylysine
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to 5-hydroxy-L-lysine.
Cross References
RefSeq
NP_001838.2
,
NP_001274689.1
,
NP_378667.1
OpenTargets
ENSG00000197565
HPA
ENSG00000197565-COL4A6
GeneCards
Q14031
Ensembl
ENSG00000197565
,
ENSP00000361290
,
ENST00000334504
,
ENSP00000334733
,
ENST00000372216
PRO
Q14031
Pharos - Targets
Q14031
Orphanet
15775
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05067 APP
20
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-713) [extracellular region]
(R-HSA-879340)
0.556
3
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
