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ANO6 [plasma membrane]
Stable Identifier
R-HSA-2684941
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Anoctamin-6, ANO6_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
Late SARS-CoV-2 Infection Events (Homo sapiens)
Induction of Cell-Cell Fusion (Homo sapiens)
S2 Cleavage by TMPRSS2 Exposes S2' Initiating Cell-Cell Fusion (Homo sapiens)
ANOs [plasma membrane] (Homo sapiens)
ANO6 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
ANO6 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
ANO6 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
ANOs transport cytosolic Cl- to extracellular region (Homo sapiens)
ANOs [plasma membrane] (Homo sapiens)
ANO6 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q4KMQ2 ANO6
Gene Names
ANO6, TMEM16F
Chain
chain:1-910
Reference Genes
BioGPS Gene:196527 ANO6
COSMIC (genes):ANO6 ANO6
CTD Gene:196527 ANO6
dbSNP Gene:196527 ANO6
ENSEMBL:ENSG00000177119 ANO6
HGNC:25240 ANO6
KEGG:hsa:196527 ANO6
Monarch:196527 ANO6
NCBI Entrez Gene:196527 ANO6
OMIM:608663 ANO6
UCSC:Q4KMQ2 ANO6
Reference Transcript
RefSeq:NM_001142678.2 ANO6
RefSeq:NM_001204803.2 ANO6
RefSeq:NM_001025356.3 ANO6
RefSeq:NM_001142679.2 ANO6
Other Identifiers
11717410_a_at
11717411_s_at
11717412_x_at
11741730_x_at
11742054_a_at
11745667_a_at
16750325
196527
224906_PM_at
224906_at
240947_PM_at
240947_at
3412572
3412573
3412574
3412576
3412584
3412587
3412590
3412596
3412597
3412602
3412603
3412609
3412610
3412611
3412612
3412614
3412618
3412619
3412621
3412623
3412626
3412628
3412631
3412632
3412633
3412635
3412642
3412643
3412644
3412645
3412646
3412651
3412652
3412653
3412654
3412655
43308_at
45340_at
7954997
A_23_P389118
A_23_P53641
A_33_P3286804
GE86288
GO:0002543
GO:0005227
GO:0005229
GO:0005244
GO:0005247
GO:0005254
GO:0005515
GO:0005829
GO:0005886
GO:0006811
GO:0006821
GO:0006869
GO:0007596
GO:0009986
GO:0016020
GO:0017121
GO:0017128
GO:0030501
GO:0032060
GO:0034220
GO:0034702
GO:0034707
GO:0034767
GO:0035579
GO:0035590
GO:0035725
GO:0043065
GO:0045794
GO:0046872
GO:0046931
GO:0046983
GO:0055085
GO:0060100
GO:0061024
GO:0061589
GO:0061590
GO:0065003
GO:0070062
GO:0070588
GO:0070821
GO:0090026
GO:0097045
GO:1902476
GO:1903766
GO:2000353
HMNXSV003008927
HMNXSV003031175
Hs.269041.0.A1_3p_at
Hs.48778.1.S1_3p_at
ILMN_1674941
PH_hs_0024852
TC12000329.hg
Participates
as a member of
ANOs [plasma membrane] (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
ANO6 [specific granule membrane]
ANO6 [tertiary granule membrane]
Inferred To
Ano6 [plasma membrane]
(Rattus norvegicus)
ANO6 [plasma membrane]
(Bos taurus)
ANO6 [plasma membrane]
(Canis familiaris)
ANO6 [plasma membrane]
(Dictyostelium discoideum)
ANO6 [plasma membrane]
(Gallus gallus)
ANO6 [plasma membrane]
(Mus musculus)
ANO6 [plasma membrane]
(Schizosaccharomyces pombe)
ANO6 [plasma membrane]
(Sus scrofa)
IST2 [plasma membrane]
(Saccharomyces cerevisiae)
ano6 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001020527.2
,
NP_001191732.1
,
NP_001136151.1
,
NP_001136150.1
ENSEMBL
ENSP00000320087
,
ENST00000425752
,
ENST00000680201
,
ENSP00000409126
,
ENSP00000506222
,
ENSP00000391417
,
ENSG00000177119
,
ENSP00000413137
,
ENST00000423947
,
ENST00000441606
,
ENST00000320560
OpenTargets
ENSG00000177119
GeneCards
ANO6
HPA
ENSG00000177119-ANO6
PRO
Q4KMQ2
Pharos - Targets
Q4KMQ2
Orphanet
ANO6
HMDB Protein
HMDBP07444
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P80370 DLK1
1
DLK1 [plasma membrane]
(R-HSA-1604447)
0.527
2
UniProt:P0DTC5 M
10
M [plasma membrane]
(R-COV-9755780)
N-glycan M [virion membrane]
(R-COV-9694385)
M [virion membrane]
(R-COV-9694320)
M [endocytic vesicle membrane]
(R-COV-9694563)
N-glycan M [endocytic vesicle membrane]
(R-COV-9694738)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694439)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694446)
M [endoplasmic reticulum membrane]
(R-COV-9767620)
nascent M [endoplasmic reticulum lumen]
(R-COV-9694279)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9694684)
0.527
2
UniProt:O00182 LGALS9
1
LGALS9 [extracellular region]
(R-HSA-5215932)
0.527
2
UniProt:Q96PC5 MIA2
1
MIA2 [endoplasmic reticulum membrane]
(R-HSA-9637821)
0.527
2
UniProt:Q8NC56 LEMD2
1
LEMD2 [nuclear envelope]
(R-HSA-3067329)
0.527
2
UniProt:P27824 CANX
3
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
CANX [lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum membrane]
(R-HSA-9932989)
0.483
2
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