Reactome | EXOC1 [plasma membrane]

EXOC1 [plasma membrane]

Stable Identifier

R-HSA-2872284

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser for interactor UniProt:Q4V328 GRAP1

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External Reference Information

External Reference

UniProt:Q9NV70 EXOC1

Gene Names

EXOC1, SEC3, SEC3L1, BM-012

Chain

initiator methionine:, chain:2-894

Reference Genes

BioGPS Gene:55763 EXOC1

COSMIC (genes):EXOC1 EXOC1

CTD Gene:55763 EXOC1

dbSNP Gene:55763 EXOC1

ENSEMBL:ENSG00000090989 EXOC1

HGNC:30380 EXOC1

Monarch:55763 EXOC1

NCBI Gene:55763 EXOC1

OMIM:607879 EXOC1

UCSC:Q9NV70 EXOC1

Reference Transcript

Other Identifiers

11718497_a_at

11743707_a_at

11757892_s_at

16966940

222127_PM_s_at

222127_s_at

2727914

2727915

2727916

2727918

2727921

2727924

2727925

2727926

2727928

2727935

2727936

2727940

2727941

2727942

2727949

2727951

2727952

2727954

2727956

2727957

2727958

2727960

2727961

2727962

2727963

2727965

2727966

2727968

2727969

2727970

2727971

44803_at

55763

56310_at

8095163

91091_at

A_14_P110427

A_14_P202235

A_23_P113966

A_23_P113972

GE55901

GO:0000145

GO:0000281

GO:0000910

GO:0005515

GO:0005546

GO:0005737

GO:0005829

GO:0005886

GO:0006887

GO:0006893

GO:0006904

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0016241

GO:0048471

GO:0051607

GO:0061024

GO:0090148

GO:0090522

GO:0090543

GO:0098542

HMNXSV003003183

HMNXSV003042601

Hs.306648.0.S1_3p_s_at

ILMN_1745583

ILMN_2347805

ILMN_2347807

PH_hs_0023111

TC04000324.hg

Participates

as a component of

Exocyst Complex [plasma membrane] (Homo sapiens)

as an input of

Exocyst complex formation (Homo sapiens)

Other forms of this molecule

EXOC1 [cytosol]

Inferred To

EXOC1 [plasma membrane] (Bos taurus)

EXOC1 [plasma membrane] (Canis familiaris)

EXOC1 [plasma membrane] (Gallus gallus)

Exoc1 [plasma membrane] (Mus musculus)

Exoc1 [plasma membrane] (Rattus norvegicus)

Sec3 [plasma membrane] (Drosophila melanogaster)

exoc1 [plasma membrane] (Dictyostelium discoideum)

sec-3 [plasma membrane] (Caenorhabditis elegans)

Cross References

OpenTargets

ENSG00000090989

ENSEMBL

ENST00000381295, ENST00000349598, ENST00000346134, ENSP00000370695, ENSP00000334431, ENSP00000326514

HPA

ENSG00000090989-EXOC1

PRO

Q9NV70

Pharos - Targets

Q9NV70

GlyGen

Q9NV70

Interactors (36)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.852	7
UniProt:Q96KP1 EXOC2	2	EXOC2 [cytosol] (R-HSA-5623376) EXOC2 [plasma membrane] (R-HSA-264887)	0.845	8
UniProt:Q7Z3B4 NUP54	2	NUP54 [cytosol] (R-HSA-9634221) NUP54 [nuclear envelope] (R-HSA-157724)	0.743	5
UniProt:Q15051 IQCB1	1	IQCB1 [cytosol] (R-HSA-5626648)	0.725	4
UniProt:O95295 SNAPIN	2	SNAPIN [Golgi membrane] (R-HSA-434344) SNAPIN [cytoplasmic vesicle membrane] (R-HSA-434204)	0.667	3
UniProt:Q13439 GOLGA4	3	GOLGA4 [cytosol] (R-HSA-6813884) p-12Y-GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] (R-HSA-9673642) GOLGA4(1-411)-PDGFRB(527-1106) fusion [plasma membrane] (R-HSA-9673590)	0.667	3
UniProt:Q9BZD4 NUF2	1	NUF2 [cytosol] (R-HSA-375300)	0.667	3
UniProt:Q13049 TRIM32	1	TRIM32 [cytosol] (R-HSA-976030)	0.638	3
UniProt:Q9Y2D4 EXC6B			0.638	3
UniProt:O60645 EXOC3	2	EXOC3 [secretory granule membrane] (R-HSA-2872286) EXOC3 [cytosol] (R-HSA-5623379)	0.638	5
UniProt:Q9UPT5 EXOC7	2	EXOC7 [cytosol] (R-HSA-5623386) EXOC7 [plasma membrane] (R-HSA-2872288)	0.638	3
UniProt:Q9H5N1 RABE2			0.638	3
UniProt:Q8TAG9 EXOC6	2	EXOC6 [plasma membrane] (R-HSA-265041) EXOC6 [cytosol] (R-HSA-5623384)	0.638	4
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-265045) EXOC5 [cytosol] (R-HSA-5623383)	0.638	4
UniProt:Q53HC9 EIPR1			0.638	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [plasma membrane] (R-HSA-264948) EXOC8 [cytosol] (R-HSA-5623388)	0.638	4
UniProt:Q8TD31-3 CCHCR1			0.556	3
UniProt:P18848 ATF4	2	ATF4 [cytosol] (R-HSA-381084) ATF4 [nucleoplasm] (R-HSA-381016)	0.556	3
UniProt:O75962 TRIO	1	TRIO [cytosol] (R-HSA-2980605)	0.553	2
UniProt:Q03001 DST	1	DST [plasma membrane] (R-HSA-447008)	0.553	2
UniProt:Q5KU26 COLEC12	2	COLEC12 [endocytic vesicle membrane] (R-HSA-2981044) COLEC12 [plasma membrane] (R-HSA-2187209)	0.553	2
UniProt:Q9H7U1 CCSE2			0.553	2
UniProt:Q9HCM1 RESF1			0.553	2
UniProt:Q9C0D2 CE295			0.553	2
UniProt:Q13813 SPTAN1	6	SPTAN1 [cytosol] (R-HSA-201601) SPTAN1(1-1185) [cytosol] (R-HSA-202944) SPTAN1(1186-2472) [cytosol] (R-HSA-202964) SPTAN1 [specific granule lumen] (R-HSA-6799533) SPTAN1 [extracellular region] (R-HSA-6806322) SPTAN1 [tertiary granule lumen] (R-HSA-6800874)	0.553	2
UniProt:Q9UPN3 MACF1			0.553	2
UniProt:Q9C026 TRIM9	1	TRIM9 [cytosol] (R-HSA-976054)	0.553	2
UniProt:O60239 3BP5			0.553	2
UniProt:Q9NRI5 DISC1			0.553	2
UniProt:Q4V328 GRAP1			0.547	2
UniProt:Q12840 KIF5A	1	KIF5A [cytosol] (R-HSA-983190)	0.547	2
UniProt:Q9BQD3 KXDL1			0.547	3
UniProt:Q13445 TMED1			0.508	2
UniProt:Q9UEU0 VTI1B	2	VTI1B [extracellular region] (R-HSA-8862983) VTI1B [platelet alpha granule lumen] (R-HSA-8862964)	0.508	2
UniProt:O95721 SNAP29	3	SNAP29 [azurophil granule membrane] (R-HSA-6799359) SNAP29 [plasma membrane] (R-HSA-2029020) SNAP29 [Golgi membrane] (R-HSA-6810997)	0.508	2
UniProt:A8K0Z3 WASH1			0.508	2

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