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SLC22A1,SLC22A2 [plasma membrane]
Stable Identifier
R-HSA-2901780
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Noradrenaline clearance from the synaptic cleft (Homo sapiens)
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)
Uptake of Noradrenaline (Homo sapiens)
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Na+/Cl- dependent neurotransmitter transporters (Homo sapiens)
Uptake of Noradrenaline (Homo sapiens)
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
OCT2 mediates tubular secretion of organic cations in the kidney (Homo sapiens)
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
OCT2 mediates tubular uptake of organic cations in the kidney (Homo sapiens)
SLC22A1,SLC22A2 [plasma membrane] (Homo sapiens)
General
This CandidateSet contains sequences identified by William Pearson's analysis of Reactome catalyst entities. Catalyst entity sequences were used to identify analagous sequences that shared overall homology and active site homology. Sequences in this Candidate set were identified in an April 24, 2012 analysis. Further candidates were identified by Ralf Stephan in a July 15, 2023 analysis.
Literature References
PubMed ID
Title
Journal
Year
Catalyst Sequence Similarity Project
Pearson, W
Participants
members
SLC22A2 [plasma membrane]
(Homo sapiens)
candidates
SLC22A1 [plasma membrane]
(Homo sapiens)
Inferred To
SLC22A1,SLC22A2 [plasma membrane]
(Bos taurus)
SLC22A1,SLC22A2 [plasma membrane]
(Caenorhabditis elegans)
SLC22A1,SLC22A2 [plasma membrane]
(Canis familiaris)
SLC22A1,SLC22A2 [plasma membrane]
(Drosophila melanogaster)
SLC22A1,SLC22A2 [plasma membrane]
(Gallus gallus)
SLC22A1,SLC22A2 [plasma membrane]
(Mus musculus)
SLC22A1,SLC22A2 [plasma membrane]
(Rattus norvegicus)
SLC22A1,SLC22A2 [plasma membrane]
(Sus scrofa)
slc22a2 [plasma membrane]
(Danio rerio)
slc22a2 [plasma membrane]
(Xenopus tropicalis)
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