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AKAP13 [cytosol]
Stable Identifier
R-HSA-2975983
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
A-kinase anchor protein 13, AKP13_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
AKAP13 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
AKAP13 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
AKAP13 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GEFs activate RHOB (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
AKAP13 [cytosol] (Homo sapiens)
RHOC GTPase cycle (Homo sapiens)
RHOC GEFs activate RHOC (Homo sapiens)
RHOC GEFs [cytosol] (Homo sapiens)
AKAP13 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12802 AKAP13
Gene Names
AKAP13, BRX, HT31, LBC
Chain
chain:1-2813
Reference Genes
BioGPS Gene:11214 AKAP13
COSMIC (genes):AKAP13 AKAP13
CTD Gene:11214 AKAP13
dbSNP Gene:11214 AKAP13
ENSEMBL:ENSG00000170776 AKAP13
ENSEMBL_homo_sapiens_GENE:ENSG00000170776.22 AKAP13
HGNC:371 AKAP13
KEGG Gene (Homo sapiens):11214 AKAP13
Monarch:11214 AKAP13
NCBI Gene:11214 AKAP13
OMIM:604686 AKAP13
UCSC:Q12802 AKAP13
Reference Transcript
RefSeq:NM_001270546.1 AKAP13
RefSeq:NM_006738.5 AKAP13
RefSeq:NM_007200.4 AKAP13
Other Identifiers
11214
11722594_at
11722595_a_at
11722596_a_at
11757869_s_at
11761456_at
16804333
208325_PM_s_at
208325_s_at
209534_PM_x_at
209534_x_at
221718_PM_s_at
221718_s_at
222024_PM_s_at
222024_s_at
224884_PM_at
224884_at
227039_PM_at
227039_at
3606315
3606316
3606317
3606318
3606335
3606345
3606347
3606348
3606349
3606350
3606351
3606352
3606353
3606354
3606359
3606360
3606361
3606362
3606363
3606364
3606365
3606368
3606369
3606380
3606384
3606389
3606393
3606395
3606397
3606399
3606405
3606408
3606409
3606420
3606421
3606431
3606435
3606437
3606438
3606439
3606441
3606442
3606444
3606447
3606449
3606450
3606452
3606453
3606454
3606457
3606458
3606459
3606460
3606463
3606464
3606470
3606471
3606473
3606474
3606475
3606476
3606477
3606478
3606479
3606480
3606481
3606482
3606483
3606484
3606485
3606486
3606487
3606488
3637362
4038891
44769_at
45330_at
45861_at
53972_at
554_at
62466_at
735_s_at
7985695
89813_at
A_14_P118293
A_14_P130346
A_23_P137276
A_24_P142095
A_24_P155761
GE79951
GE86371
GO:0003013
GO:0005078
GO:0005085
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0005856
GO:0005938
GO:0007010
GO:0007186
GO:0007507
GO:0015629
GO:0016020
GO:0023052
GO:0030154
GO:0030864
GO:0031267
GO:0035023
GO:0035025
GO:0043123
GO:0043226
GO:0043410
GO:0046872
GO:0048856
GO:0051018
GO:0051056
GO:0055007
GO:0060090
GO:0060297
GO:0060348
GO:0071875
GO:0086023
GO:0098772
GO:0110165
HMNXSV003051410
Hs.29893.0.S1_3p_at
Hs.301946.1.A1_3p_a_at
Hs.302741.0.S1_3p_at
Hs.306619.0.S1_3p_s_at
ILMN_1709101
ILMN_1752247
ILMN_2396956
PH_hs_0023930
TC15000827.hg
U03634_at
g184434_3p_s_at
g5803057_3p_a_at
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
RHOC GEFs [cytosol] (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
gxcN [cytosol]
(Dictyostelium discoideum)
Akap13 [cytosol]
(Mus musculus)
Akap13 [cytosol]
(Rattus norvegicus)
AKAP13 [cytosol]
(Bos taurus)
AKAP13 [cytosol]
(Caenorhabditis elegans)
AKAP13 [cytosol]
(Canis familiaris)
AKAP13 [cytosol]
(Gallus gallus)
AKAP13 [cytosol]
(Sus scrofa)
cyst [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_006729.4
,
NP_009131.2
,
NP_001257475.1
OpenTargets
ENSG00000170776
HPA
ENSG00000170776-AKAP13
GeneCards
Q12802
Ensembl
ENST00000394518
,
ENST00000361243
,
ENSP00000378026
,
ENSG00000170776
,
ENSP00000354718
,
ENST00000560302
,
ENSP00000453634
PRO
Q12802
Pharos - Targets
Q12802
HMDB Protein
HMDBP07437
PDB
2DRN
,
6BCA
,
2LG1
,
4D0N
,
4D0O
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31946 YWHAB
1
YWHAB [cytosol]
(R-HSA-48888)
0.749
5
UniProt:P63104 YWHAZ
2
YWHAZ [nucleoplasm]
(R-HSA-450469)
YWHAZ [cytosol]
(R-HSA-206099)
0.65
3
UniProt:P03372 ESR1
8
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.593
3
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