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VAMP1 [synaptic vesicle membrane]
Stable Identifier
R-HSA-2976040
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
synaptic vesicle membrane
Synonyms
Vesicle-associated membrane protein 1, VAMP1_HUMAN
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Neurotoxicity of clostridium toxins (Homo sapiens)
Toxicity of botulinum toxin type D (botD) (Homo sapiens)
botD LC cleaves target cell VAMP1 (Homo sapiens)
VAMP1 [synaptic vesicle membrane] (Homo sapiens)
Toxicity of botulinum toxin type F (botF) (Homo sapiens)
botF LC cleaves target cell VAMP1 (Homo sapiens)
VAMP1 [synaptic vesicle membrane] (Homo sapiens)
Toxicity of botulinum toxin type G (botG) (Homo sapiens)
botG LC cleaves target cell VAMP1 (Homo sapiens)
VAMP1 [synaptic vesicle membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P23763 VAMP1
Gene Names
VAMP1, SYB1
Chain
chain:1-118
Reference Genes
BioGPS Gene:6843 VAMP1
COSMIC (genes):VAMP1 VAMP1
CTD Gene:6843 VAMP1
dbSNP Gene:6843 VAMP1
ENSEMBL:ENSG00000139190 VAMP1
HGNC:12642 VAMP1
KEGG:hsa:6843 VAMP1
Monarch:6843 VAMP1
NCBI Gene:6843 VAMP1
OMIM:185880 VAMP1
UCSC:P23763 VAMP1
Reference Transcript
RefSeq:NM_016830.3 VAMP1
RefSeq:NM_014231.4 VAMP1
RefSeq:NM_199245.2 VAMP1
RefSeq:NM_001297438.1 VAMP1
Participates
as an input of
botG LC cleaves target cell VAMP1 (Homo sapiens)
botD LC cleaves target cell VAMP1 (Homo sapiens)
botF LC cleaves target cell VAMP1 (Homo sapiens)
Other forms of this molecule
VAMP1(84-118) [synaptic vesicle membrane]
VAMP1(1-83) [cytosol]
VAMP1(1-61) [cytosol]
VAMP1(62-118) [synaptic vesicle membrane]
VAMP1(1-60) [cytosol]
VAMP1(61-118) [synaptic vesicle membrane]
Cross References
ENSEMBL
ENST00000400911
,
ENST00000361716
,
ENSP00000355122
,
ENSP00000383702
,
ENSG00000139190
,
ENSP00000379602
,
ENST00000396308
OpenTargets
ENSG00000139190
GeneCards
VAMP1
HPA
ENSG00000139190-VAMP1
PRO
P23763
Pharos - Targets
P23763
Orphanet
VAMP1
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O95721 SNAP29
3
SNAP29 [azurophil granule membrane]
(R-HSA-6799359)
SNAP29 [plasma membrane]
(R-HSA-2029020)
SNAP29 [Golgi membrane]
(R-HSA-6810997)
0.556
3
UniProt:Q8N6L0 KASH5
0.556
3
UniProt:Q12846 STX4
4
STX4 [plasma membrane]
(R-HSA-181519)
STX4 [phagocytic vesicle membrane]
(R-HSA-2029044)
STX4 [cytosol]
(R-HSA-114505)
p-STX4 [cytosol]
(R-HSA-114681)
0.556
3
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