Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
SYDE1 [cytosol]
Stable Identifier
R-HSA-2980861
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Rho GTPase-activating protein SYDE1, SYDE1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
CDC42 GTPase cycle (Homo sapiens)
CDC42 GAPs stimulate CDC42 GTPase activity (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
RAC2 GTPase cycle (Homo sapiens)
RAC2 GAPs stimulate RAC2 GTPase activity (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
RAC3 GTPase cycle (Homo sapiens)
RAC3 GAPs stimulate RAC3 GTPase activity (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
RHOF GTPase cycle (Homo sapiens)
RHOF GAPs stimulate RHOF GTPase activity (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ GAPs stimulate RHOJ GTPase activity (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
RHOQ GTPase cycle (Homo sapiens)
RHOQ GAPs stimulate RHOQ GTPase activity (Homo sapiens)
RHOQ GAPs [cytosol] (Homo sapiens)
SYDE1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q6ZW31 SYDE1
Gene Names
SYDE1
Chain
chain:1-735
Reference Genes
BioGPS Gene:85360 SYDE1
COSMIC (genes):SYDE1 SYDE1
CTD Gene:85360 SYDE1
dbSNP Gene:85360 SYDE1
ENSEMBL:ENSG00000105137 SYDE1
ENSEMBL_homo_sapiens_GENE:ENSG00000105137.13 SYDE1
HGNC:25824 SYDE1
KEGG Gene (Homo sapiens):85360 SYDE1
Monarch:85360 SYDE1
NCBI Gene:85360 SYDE1
OMIM:617377 SYDE1
UCSC:Q6ZW31 SYDE1
Reference Transcript
RefSeq:NM_033025.5 SYDE1
RefSeq:NM_001300910.1 SYDE1
Other Identifiers
11741657_a_at
11741658_s_at
11744703_x_at
11754331_a_at
11754332_x_at
16859105
212962_PM_at
212962_at
216271_PM_x_at
216271_x_at
216272_3p_x_at
216272_PM_x_at
216272_x_at
32900_at
3823022
3823023
3823025
3823026
3823029
3823031
3823032
3823034
3823036
3823038
3823039
3823040
3823041
3823042
3823043
44702_PM_at
44702_at
8026407
85360
A_14_P136461
A_23_P101796
GE85566
GO:0005096
GO:0005886
GO:0007010
GO:0007165
GO:0016477
GO:0022414
GO:0023052
GO:0030036
GO:0030695
GO:0046578
GO:0048856
GO:0048870
GO:0051493
GO:0090630
GO:0097060
GO:0098772
GO:1901165
HMNXSV003036356
Hs.9291.0.S1_3p_s_at
Hs.9291.2.S1_3p_a_at
ILMN_1755822
PH_hs_0000970
PH_hs_0030736
TC19000269.hg
Participates
as a candidate of
RHOQ GAPs [cytosol] (Homo sapiens)
CDC42 GAPs [cytosol] (Homo sapiens)
RAC2 GAPs [cytosol] (Homo sapiens)
RHOF GAPs [cytosol] (Homo sapiens)
RHOJ GAPs [cytosol] (Homo sapiens)
RAC3 GAPs [cytosol] (Homo sapiens)
Inferred To
SYDE1 [cytosol]
(Bos taurus)
SYDE1 [cytosol]
(Canis familiaris)
SYDE1 [cytosol]
(Gallus gallus)
SYDE1 [cytosol]
(Sus scrofa)
RhoGAP100F [cytosol]
(Drosophila melanogaster)
syd-1 [cytosol]
(Caenorhabditis elegans)
Syde1 [cytosol]
(Mus musculus)
Syde1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_149014.3
,
NP_001287839.1
OpenTargets
ENSG00000105137
GeneCards
Q6ZW31
HPA
ENSG00000105137-SYDE1
Ensembl
ENST00000342784
,
ENST00000600440
,
ENSP00000470733
,
ENSG00000105137
,
ENSP00000341489
PRO
Q6ZW31
Pharos - Targets
Q6ZW31
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62258 YWHAE
1
YWHAE [cytosol]
(R-HSA-194368)
0.527
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text