Reactome | ARL6IP5 [cytosol]

ARL6IP5 [cytosol]

Stable Identifier

R-HSA-2980942

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

PRA1 family protein 3, PRAF3_HUMAN

Locations in the PathwayBrowser for interactor UniProt:P01116 KRAS

Expand all

External Reference Information

External Reference

UniProt:O75915 ARL6IP5

Gene Names

ARL6IP5, DERP11, JWA, PRA2, PRAF3, HSPC127

Chain

chain:1-188

Reference Genes

BioGPS Gene:10550 ARL6IP5

COSMIC (genes):ARL6IP5 ARL6IP5

CTD Gene:10550 ARL6IP5

dbSNP Gene:10550 ARL6IP5

ENSEMBL:ENSG00000144746 ARL6IP5

HGNC:16937 ARL6IP5

KEGG:hsa:10550 ARL6IP5

Monarch:10550 ARL6IP5

NCBI Gene:10550 ARL6IP5

OMIM:605709 ARL6IP5

UCSC:O75915 ARL6IP5

Reference Transcript

RefSeq:NM_006407.3 ARL6IP5

Other Identifiers

10550

11715955_a_at

11715956_s_at

11748862_s_at

11748863_x_at

16942560

200760_PM_s_at

200760_s_at

200761_PM_s_at

200761_s_at

2628687

2628688

2628689

2628691

2628694

2628695

2628696

2628697

2628698

2628699

2628700

2628701

2844078

39091_at

8080926

A_14_P120024

A_14_P200099

A_23_P166640

A_24_P257348

GE54622

GO:0002037

GO:0003674

GO:0005515

GO:0005737

GO:0005783

GO:0005789

GO:0005829

GO:0005856

GO:0005886

GO:0006575

GO:0006749

GO:0006790

GO:0007611

GO:0008631

GO:0010917

GO:0015031

GO:0015813

GO:0016020

GO:0032874

GO:0034599

GO:0043065

GO:0043226

GO:0043280

GO:0050877

GO:0051051

GO:0055085

GO:0071407

GO:0072659

GO:0098712

GO:0099523

HMNXSV003049225

Hs.92384.0.S1_3p_a_at

ILMN_1769810

PH_hs_0005117

PH_hs_0031409

TC03000417.hg

g7669496_3p_a_at

This entity regulates

Negatively

SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Homo sapiens)

Inferred To

ARL6IP5 [cytosol] (Bos taurus)

ARL6IP5 [cytosol] (Canis familiaris)

ARL6IP5 [cytosol] (Gallus gallus)

ARL6IP5 [cytosol] (Sus scrofa)

arl6ip5b [cytosol] (Danio rerio)

Arl6ip5 [cytosol] (Mus musculus)

Arl6ip5 [cytosol] (Rattus norvegicus)

Jwa [cytosol] (Drosophila melanogaster)

arl6ip5 [cytosol] (Xenopus tropicalis)

praf-3 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006398.1

ENSEMBL

ENSP00000273258, ENST00000273258

OpenTargets

ENSG00000144746

HPA

ENSG00000144746-ARL6IP5

PRO

O75915

Pharos - Targets

O75915

GlyGen

O75915

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60831 PRAF2			0.621	4
UniProt:Q9NQG6 MID51			0.556	3
UniProt:Q96GF1 RNF185	1	RNF185 [endoplasmic reticulum membrane] (R-HSA-8861819)	0.556	3
UniProt:P13598 ICAM2	1	ICAM2 [plasma membrane] (R-HSA-197852)	0.527	3
UniProt:P32241 VIPR1	1	VIPR1 [plasma membrane] (R-HSA-420157)	0.527	2
UniProt:P25090 FPR2	4	FPR2 [plasma membrane] (R-HSA-416408) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335) FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [tertiary granule membrane] (R-HSA-6803296)	0.527	2
UniProt:O60636 TSN2			0.527	2
UniProt:Q9NQC3 RTN4	1	RTN4 [plasma membrane] (R-HSA-194556)	0.527	2
UniProt:P54709 ATP1B3	1	ATP1B3 [plasma membrane] (R-HSA-375073)	0.527	2
UniProt:O95136 S1PR2	1	S1PR2 [plasma membrane] (R-HSA-419419)	0.527	2
UniProt:P25103 TACR1	2	TACR1 [plasma membrane] (R-HSA-380103) TACR1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869122)	0.527	2
UniProt:Q86VR2 RETR3			0.527	2
UniProt:P06028 GYPB	1	GYPB [plasma membrane] (R-HSA-8867209)	0.527	2
UniProt:A5X5Y0 HTR3E	1	HTR3E [plasma membrane] (R-HSA-975278)	0.527	3
UniProt:Q9P296 C5AR2	1	C5AR2 [plasma membrane] (R-HSA-964798)	0.527	2
UniProt:P01116 KRAS	20	S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674814) p-Y32-S-Farn-Me-PalmS KRAS [plasma membrane] (R-HSA-9674821) KRAS A146T [plasma membrane] (R-HSA-9649623) KRAS K147E [plasma membrane] (R-HSA-9651169) KRAS K147T [plasma membrane] (R-HSA-9651180) KRAS V14G [plasma membrane] (R-HSA-9651295) KRAS K147N [plasma membrane] (R-HSA-9651177) KRAS A146V [plasma membrane] (R-HSA-9649626) KRAS A146S [plasma membrane] (R-HSA-9649621) KRAS A146P [plasma membrane] (R-HSA-9649617) KRAS P34R [plasma membrane] (R-HSA-9651276) KRAS P34L [plasma membrane] (R-HSA-9651269) KRAS G12A [plasma membrane] (R-HSA-9649088) KRAS G12R [plasma membrane] (R-HSA-9649090) KRAS G13V [plasma membrane] (R-HSA-9649644) KRAS G13S [plasma membrane] (R-HSA-9649642) KRAS G13C [plasma membrane] (R-HSA-9649636) KRAS G13R [plasma membrane] (R-HSA-9649639) KRAS G13A [plasma membrane] (R-HSA-9649632) KRAS K5N [plasma membrane] (R-HSA-9651361)	0.519	2
UniProt:P30153 PPP2R1A	2	PPP2R1A [cytosol] (R-HSA-165982) PPP2R1A [nucleoplasm] (R-HSA-165968)	0.508	2

Cite Us!