SENP1 [nucleoplasm]

Stable Identifier
R-HSA-2984299
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Sentrin-specific protease 1 ecNumber3.4.22.68/ecNumber, SENP1_HUMAN
Icon
SENP1 [nucleoplasm] icon
SENP1 [nucleoplasm] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
14563852 Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1

O'Hare, P, Bailey, D

J. Biol. Chem. 2004
16253240 Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1

Lee, SJ, Kim, Y, Sung, KS, Choi, CY, Kim, YO, Kim, YH

FEBS Lett. 2005
10652325 Differential regulation of sentrinized proteins by a novel sentrin-specific protease

Millas, S, Maul, GG, Yeh, ET, Gong, L

J. Biol. Chem. 2000
External Reference Information
External Reference
UniProt:Q9P0U3 SENP1
Gene Names
SENP1
Chain
chain:1-644
Reference Genes
BioGPS Gene:29843 SENP1
COSMIC (genes):SENP1 SENP1
CTD Gene:29843 SENP1
dbSNP Gene:29843 SENP1
ENSEMBL:ENSG00000079387 SENP1
HGNC:17927 SENP1
KEGG:hsa:29843 SENP1
Monarch:29843 SENP1
NCBI Gene:29843 SENP1
OMIM:612157 SENP1
UCSC:Q9P0U3 SENP1
Reference Transcript
Other Identifiers
11739940_a_at
11739941_s_at
11764136_at
1552812_PM_a_at
1552812_a_at
16763853
226619_PM_at
226619_at
29843
3452964
3452965
3452967
3452969
3452971
3452972
3452973
3452974
3452975
3452977
3452979
3452980
3452987
3452988
3452989
3452990
3452991
3452992
3452993
3452994
3452995
3452996
3452998
3452999
3453000
3453001
3453002
3453003
3453004
3453006
3453008
3453009
3453010
3453011
3453013
3453014
3453015
3453016
3453017
3453019
3453020
3453021
3453022
64891_at
66230_at
7962760
A_23_P204536
A_24_P167412
A_33_P3304528
GE483673
GE81939
GO:0003824
GO:0004175
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005925
GO:0006355
GO:0006508
GO:0006919
GO:0008234
GO:0016787
GO:0016925
GO:0016926
GO:0016929
GO:0031965
GO:0043226
GO:0043488
GO:0045944
GO:0070139
GO:0097190
GO:0098978
GO:0140096
GO:0150052
HMNXSV003032392
Hs.66450.0.S2_3p_at
Hs2.66450.1.S1_3p_s_at
PH_hs_0024495
TC12001443.hg
Participates
as a member of
Other forms of this molecule
SENP1 [cytosol]
Inferred To
Ulp1 [nucleoplasm] (Drosophila melanogaster)
ulp-1 [nucleoplasm] (Caenorhabditis elegans)
ulp1 [nucleoplasm] (Schizosaccharomyces pombe)
SENP1 [nucleoplasm] (Bos taurus)
SENP1 [nucleoplasm] (Canis familiaris)
SENP1 [nucleoplasm] (Dictyostelium discoideum)
SENP1 [nucleoplasm] (Gallus gallus)
SENP1 [nucleoplasm] (Plasmodium falciparum)
SENP1 [nucleoplasm] (Sus scrofa)
senp1 [nucleoplasm] (Xenopus tropicalis)
Senp1 [nucleoplasm] (Mus musculus)
Senp1 [nucleoplasm] (Rattus norvegicus)
ULP2 [nucleoplasm] (Saccharomyces cerevisiae)
Cross References
RefSeq
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
HPA
ZINC - Substances
ZINC target
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
Interactors (3)
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