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SUMO3(1-103) [nucleoplasm]
Stable Identifier
R-HSA-2990830
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
proSUMO3, Small ubiquitin-related modifier 3, SUMO3_HUMAN, SUMO3
Icon
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
Processing and activation of SUMO (Homo sapiens)
SUMO is proteolytically processed (Homo sapiens)
SENP1,2,5 proteolytically process SUMO3 (Homo sapiens)
SUMO3(1-103) [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P55854 SUMO3
Gene Names
SUMO3, SMT3A, SMT3H1
Chain
chain:1-92, propeptide:93-103
Reference Genes
BioGPS Gene:6612 SUMO3
COSMIC (genes):SUMO3 SUMO3
CTD Gene:6612 SUMO3
dbSNP Gene:6612 SUMO3
ENSEMBL:ENSG00000184900 SUMO3
ENSEMBL_homo_sapiens_GENE:ENSG00000184900.16 SUMO3
HGNC:11124 SUMO3
KEGG Gene (Homo sapiens):6612 SUMO3
Monarch:6612 SUMO3
NCBI Gene:6612 SUMO3
OMIM:602231 SUMO3
UCSC:P55854 SUMO3
Reference Transcript
RefSeq:NM_006936.2 SUMO3
RefSeq:NM_001286416.1 SUMO3
Other Identifiers
11721797_at
11721798_a_at
11764238_at
16926433
200739_PM_s_at
200739_s_at
200740_PM_s_at
200740_s_at
38738_at
3934670
3934671
3934672
3934673
3934674
3934678
3934685
3934686
3934688
6612
8070811
A_23_P102937
A_24_P245767
GE60218
GO:0000776
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0016605
GO:0016925
GO:0031386
GO:0036211
GO:0043226
GO:0043392
GO:0044389
GO:1900180
HMNXSV003052673
Hs.85119.0.A1_3p_a_at
ILMN_1725642
PH_hs_0004814
PH_hs_0031377
TC21000536.hg
X99584_at
g5902095_3p_a_at
Participates
as an input of
SENP1,2,5 proteolytically process SUMO3 (Homo sapiens)
Other forms of this molecule
UBA2-G92-SUMO3 [nucleoplasm]
lysyl-G92-SUMOyl-K11-SUMO3 [nucleoplasm]
SUMO3 [nucleoplasm]
UBE2I-G92-SUMO3 [nucleoplasm]
Inferred To
SUMO3(1-103) [nucleoplasm]
(Dictyostelium discoideum)
SUMO3(1-103) [nucleoplasm]
(Plasmodium falciparum)
Sumo [nucleoplasm]
(Drosophila melanogaster)
SUMO3 [nucleoplasm]
(Bos taurus)
SUMO3 [nucleoplasm]
(Canis familiaris)
SUMO3 [nucleoplasm]
(Gallus gallus)
SUMO3 [nucleoplasm]
(Sus scrofa)
sumo3 [nucleoplasm]
(Danio rerio)
sumo3 [nucleoplasm]
(Xenopus tropicalis)
Sumo3 [nucleoplasm]
(Mus musculus)
Sumo3 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_001273345.1
,
NP_008867.2
OpenTargets
ENSG00000184900
GeneCards
P55854
HPA
ENSG00000184900-SUMO3
Ensembl
ENSP00000330343
,
ENSP00000409666
,
ENSG00000184900
,
ENST00000411651
,
ENST00000332859
PRO
P55854
Pharos - Targets
P55854
PDB
2MP2
,
7ZJU
,
6NNQ
,
6K5R
,
2IO1
,
7R2E
,
1U4A
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9HC62 SENP2
1
SENP2 [nucleoplasm]
(R-HSA-2984298)
0.799
7
UniProt:Q5W0Q7 USPL1
0.782
17
UniProt:P63279 UBE2I
9
monoSUMO1-K14-UBE2I [nucleoplasm]
(R-HSA-4085358)
UBE2I [nuclear envelope]
(R-HSA-4655408)
SUMO2-C93-UBE2I [cytosol]
(R-HSA-4656944)
SUMO3-C93-UBE2I [nucleoplasm]
(R-HSA-3730629)
UBE2I [cytosol]
(R-HSA-4655342)
SUMO1-C93-UBE2I [cytosol]
(R-HSA-4656909)
SUMO2-C93-UBE2I [nucleoplasm]
(R-HSA-3730619)
SUMO1-C93-UBE2I [nucleoplasm]
(R-HSA-3730617)
UBE2I [nucleoplasm]
(R-HSA-912481)
0.669
3
UniProt:Q6PEW1 ZCH12
0.666
4
UniProt:Q99700-5 Q997005
0.556
3
UniProt:A4D161 F221A
0.556
3
UniProt:O15060 ZBT39
0.556
3
UniProt:Q86T24 KAISO
0.556
3
IntAct:EBI-16436244 CCSB ORF ID
0.556
3
UniProt:Q96IT1 ZNF496
1
ZNF496 [nucleoplasm]
(R-HSA-1247860)
0.556
3
UniProt:P54253 ATX1
0.556
6
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
9
UniProt:P62990 UBIQ
0.544
2
UniProt:P23497 SP100
3
polySUMO2-K297-SP100 [nucleoplasm]
(R-HSA-3000454)
monoSUMO1-K297-SP100 [nucleoplasm]
(R-HSA-3000382)
SP100 [nucleoplasm]
(R-HSA-1031705)
0.524
2
UniProt:O43290 SART1
1
SART1 [nucleoplasm]
(R-HSA-4615999)
0.499
2
UniProt:Q86X55 CARM1
1
CARM1 [nucleoplasm]
(R-HSA-400139)
0.499
2
UniProt:P11474 ESRRA
1
ESRRA [nucleoplasm]
(R-HSA-446159)
0.463
2
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