Transfer of SUMO2 from E1 to UBE2I (UBC9)

Stable Identifier
R-HSA-2993790
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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SUMO2 is transferred from cysteine-173 of UBA2 to cysteine-93 of UBC9 (UBE2I) in a transthiolation reaction (Tatham et al. 2001, Werner et al. 2009).
Literature References
PubMed ID Title Journal Year
19107418 Performing in vitro sumoylation reactions using recombinant enzymes

Moutty, MC, Melchior, F, Möller, U, Werner, A

Methods Mol. Biol. 2009
11451954 Polymeric chains of SUMO-2 and SUMO-3 are conjugated to protein substrates by SAE1/SAE2 and Ubc9

Vaughan, OA, Tatham, MH, Botting, CH, Naismith, JH, Desterro, JM, Jaffray, E, Hay, RT

J. Biol. Chem. 2001
Participants
Participates
Catalyst Activity

SUMO transferase activity of UBA2:SAE1 [nucleoplasm]

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