Reactome | GRIA1 [plasma membrane]

GRIA1 [plasma membrane]

Stable Identifier

R-HSA-3004495

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Glutamate receptor 1, GluR1, GRIA1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P42261 GRIA1

Gene Names

GRIA1, GLUH1, GLUR1, GLUR1

Chain

signal peptide:1-18, chain:19-906

Reference Genes

BioGPS Gene:2890 GRIA1

COSMIC (genes):GRIA1 GRIA1

CTD Gene:2890 GRIA1

dbSNP Gene:2890 GRIA1

ENSEMBL:ENSG00000155511 GRIA1

HGNC:4571 GRIA1

KEGG:hsa:2890 GRIA1

Monarch:2890 GRIA1

NCBI Gene:2890 GRIA1

OMIM:138248 GRIA1

UCSC:P42261 GRIA1

Reference Transcript

Other Identifiers

11739499_a_at

11745982_a_at

11745983_x_at

11748236_a_at

16991296

209793_PM_at

209793_at

211520_PM_s_at

211520_s_at

2836265

2836266

2836267

2836268

2836270

2836271

2836272

2836286

2836300

2836314

2836315

2836316

2836317

2836318

2836322

2836323

2836324

2836326

2836327

2836331

2836332

2836333

2836334

2836349

2836350

2836351

2836367

2836368

2836375

2836376

2836377

2836383

2836384

2836385

2836386

2836387

2836388

2890

36853_at

36854_s_at

36855_r_at

8109383

A_14_P106001

A_23_P303072

GE58235

GO:0001540

GO:0001919

GO:0001965

GO:0004970

GO:0004971

GO:0005215

GO:0005216

GO:0005515

GO:0005576

GO:0005768

GO:0005769

GO:0005783

GO:0005789

GO:0005829

GO:0005886

GO:0005911

GO:0006811

GO:0007165

GO:0007215

GO:0007268

GO:0007416

GO:0007616

GO:0008021

GO:0008066

GO:0008092

GO:0008179

GO:0008328

GO:0009410

GO:0009636

GO:0009744

GO:0009897

GO:0009986

GO:0010226

GO:0010628

GO:0012507

GO:0014069

GO:0014070

GO:0015276

GO:0016020

GO:0016192

GO:0019228

GO:0019722

GO:0019865

GO:0019901

GO:0019904

GO:0021510

GO:0021987

GO:0022824

GO:0022849

GO:0023052

GO:0030165

GO:0030425

GO:0030666

GO:0030672

GO:0031090

GO:0031267

GO:0031410

GO:0031489

GO:0031594

GO:0031623

GO:0031667

GO:0031681

GO:0031698

GO:0031901

GO:0032279

GO:0032281

GO:0032355

GO:0032590

GO:0032591

GO:0032809

GO:0032991

GO:0033116

GO:0034220

GO:0034330

GO:0034765

GO:0035235

GO:0035249

GO:0035254

GO:0036477

GO:0038023

GO:0042220

GO:0042734

GO:0042802

GO:0042995

GO:0043005

GO:0043025

GO:0043197

GO:0043198

GO:0043226

GO:0043278

GO:0043434

GO:0044297

GO:0044308

GO:0044309

GO:0045202

GO:0045211

GO:0045471

GO:0045838

GO:0046685

GO:0048167

GO:0048266

GO:0048787

GO:0048856

GO:0050804

GO:0050806

GO:0050877

GO:0051018

GO:0051428

GO:0051602

GO:0055037

GO:0055038

GO:0055085

GO:0060076

GO:0060089

GO:0060291

GO:0060292

GO:0060992

GO:0071230

GO:0071242

GO:0071359

GO:0071363

GO:0071375

GO:0071407

GO:0071418

GO:0090326

GO:0097060

GO:0097110

GO:0098793

GO:0098794

GO:0098839

GO:0098978

GO:0099092

GO:0099505

GO:0099507

GO:0099544

GO:0099566

GO:0099583

GO:1904315

GO:1905232

GO:1990416

GO:1990635

GO:1990708

GO:1990911

GO:2000463

HMNXSV003051400

Hs.7117.1.A2_3p_at

ILMN_2203299

M64752_at

M81886_s_at

PH_hs_0021980

TC05000849.hg

Z70220_at

g183280_3p_a_at

Participates

as a component of

Other forms of this molecule

GRIA1 [endocytic vesicle membrane]

p-S849-GRIA1 [plasma membrane]

GRIA1 [endoplasmic reticulum membrane]

GRIA1 [ER to Golgi transport vesicle membrane]

GRIA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Inferred To

glr-4 [plasma membrane] (Caenorhabditis elegans)

glr-1 [plasma membrane] (Caenorhabditis elegans)

Ekar [plasma membrane] (Drosophila melanogaster)

Homologues of GRIA1 [plasma membrane] (Caenorhabditis elegans)

Homologues of GRIA1 [plasma membrane] (Drosophila melanogaster)

glr-7 [plasma membrane] (Caenorhabditis elegans)

gria1a [plasma membrane] (Danio rerio)

Ir21a [plasma membrane] (Drosophila melanogaster)

gria1 [plasma membrane] (Xenopus tropicalis)

GRIA1 [plasma membrane] (Bos taurus)

GRIA1 [plasma membrane] (Caenorhabditis elegans)

GRIA1 [plasma membrane] (Canis familiaris)

GRIA1 [plasma membrane] (Gallus gallus)

GRIA1 [plasma membrane] (Mus musculus)

GRIA1 [plasma membrane] (Rattus norvegicus)

GRIA1 [plasma membrane] (Sus scrofa)

Ir25a [plasma membrane] (Drosophila melanogaster)

DmelCG11155 [plasma membrane] (Drosophila melanogaster)

GluRIA [plasma membrane] (Drosophila melanogaster)

glr-6 [plasma membrane] (Caenorhabditis elegans)

GluRIB [plasma membrane] (Drosophila melanogaster)

glr-5 [plasma membrane] (Caenorhabditis elegans)

Ir93a [plasma membrane] (Drosophila melanogaster)

Ir76b [plasma membrane] (Drosophila melanogaster)

glr-2 [plasma membrane] (Caenorhabditis elegans)

Ir8a [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_001244952.1, NP_001107655.1, NP_001244951.1, NP_000818.2, NP_001244948.1, NP_001244950.1

Guide to Pharmacology - Targets

444

OpenTargets

ENSG00000155511

ENSEMBL

ENSP00000427920, ENST00000285900, ENSP00000428994, ENSP00000285900, ENST00000521843, ENSP00000427864, ENST00000518783, ENSP00000415569, ENSP00000339343, ENST00000518142, ENST00000448073, ENST00000340592

HPA

ENSG00000155511-GRIA1

ZINC target

P42261

PRO

P42261

Pharos - Targets

P42261

Orphanet

GRIA1

GlyGen

P42261

PDB

6X5Q

HMDB Protein

HMDBP02795

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14457 BECN1	4	BECN1 [cytosol] (R-HSA-1632841) p-S15-BECN1 [cytosol] (R-HSA-5682391) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) K63polyUb-BECN1 [cytosol] (R-HSA-6782989)	0.556	3
UniProt:Q9UNY5 ZN232			0.556	3
UniProt:Q9UIH9 KLF15	1	KLF15 [nucleoplasm] (R-HSA-8878735)	0.556	3
UniProt:Q15907 RAB11B	3	RAB11B [recycling endosome membrane] (R-HSA-8854762) GGC-RAB11B [cytosol] (R-HSA-8873766) RAB11B [cytosol] (R-HSA-8873671)	0.556	3
UniProt:Q6XD76 ASCL4			0.556	3

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