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RHOJ [plasma membrane]
Stable Identifier
R-HSA-3006725
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Rho-related GTP-binding protein RhoJ, RHOJ_HUMAN, TCL
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOJ GTPase cycle (Homo sapiens)
RHOJ GAPs stimulate RHOJ GTPase activity (Homo sapiens)
RHOJ:GDP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
RHOJ:GTP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
RHOJ GEFs activate RHOJ (Homo sapiens)
RHOJ:GDP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
RHOJ:GTP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
RHOJ binds effectors at the plasma membrane (Homo sapiens)
RHOJ:GTP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
RHOJ:GTP:RHOJ effectors [plasma membrane] (Homo sapiens)
RHOJ:GTP [plasma membrane] (Homo sapiens)
RHOJ [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H4E5 RHOJ
Gene Names
RHOJ, ARHJ, RASL7B, RHOI, TCL
Chain
chain:1-211, propeptide:212-214
Reference Genes
BioGPS Gene:57381 RHOJ
COSMIC (genes):RHOJ RHOJ
CTD Gene:57381 RHOJ
dbSNP Gene:57381 RHOJ
ENSEMBL:ENSG00000126785.13 RHOJ
HGNC:688 RHOJ
KEGG Gene (Homo sapiens):57381 RHOJ
Monarch:57381 RHOJ
NCBI Gene:57381 RHOJ
OMIM:607653 RHOJ
UCSC:Q9H4E5 RHOJ
Reference Transcript
RefSeq:NM_020663.4 RHOJ
Other Identifiers
0003130050
11740182_a_at
11749864_a_at
11756022_a_at
11759345_at
1555233_PM_at
1555233_at
1555234_PM_a_at
1555234_a_at
16785127
235131_3p_at
235131_PM_at
235131_at
235489_PM_at
235489_at
238905_PM_at
238905_at
238906_PM_s_at
238906_s_at
243481_PM_at
243481_at
3539500
3539501
3539522
3539531
3539532
3539533
3539539
3539540
3539541
3539542
3539543
3539544
3539545
3539546
3539547
3539548
54871_at
57381
60013_at
60014_r_at
65523_at
67288_at
67289_g_at
7974902
A_23_P316012
A_24_P82032
GE88766
GO:0000166
GO:0001525
GO:0003924
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005886
GO:0006897
GO:0007010
GO:0007163
GO:0007264
GO:0007266
GO:0008360
GO:0010594
GO:0016020
GO:0016192
GO:0016787
GO:0023052
GO:0030036
GO:0032488
GO:0043226
GO:0048856
GO:0048870
GO:0061299
GO:0070062
GO:0090050
GO:1903670
HMNXSV003007668
HMNXSV003017544
Hs.243010.0.A1_3p_at
Hs.243010.0.A1_3p_s_at
Hs.243010.1.A1_3p_at
Hs.249989.0.A1_3p_at
Hs.270219.0.A1_3p_at
Hs.270219.0.A1_3p_s_at
Hs2.243010.2.S1_3p_at
ILMN_1678215
ILMN_2107613
PH_hs_0012985
TC14000377.hg
Participates
as a component of
RHOJ:GDP [plasma membrane] (Homo sapiens)
RHOJ:GTP [plasma membrane] (Homo sapiens)
Inferred To
rhoj [plasma membrane]
(Xenopus tropicalis)
RHOJ [plasma membrane]
(Bos taurus)
RHOJ [plasma membrane]
(Caenorhabditis elegans)
RHOJ [plasma membrane]
(Canis familiaris)
RHOJ [plasma membrane]
(Danio rerio)
RHOJ [plasma membrane]
(Drosophila melanogaster)
RHOJ [plasma membrane]
(Gallus gallus)
RHOJ [plasma membrane]
(Mus musculus)
RHOJ [plasma membrane]
(Saccharomyces cerevisiae)
RHOJ [plasma membrane]
(Schizosaccharomyces pombe)
RHOJ [plasma membrane]
(Sus scrofa)
Rhoj [plasma membrane]
(Rattus norvegicus)
crp-1 [plasma membrane]
(Caenorhabditis elegans)
Homologues of RHOJ [plasma membrane]
(Caenorhabditis elegans)
Homologues of RHOJ [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
NP_065714.1
OpenTargets
ENSG00000126785
GeneCards
Q9H4E5
HPA
ENSG00000126785-RHOJ
Ensembl
ENSP00000316729
,
ENSG00000126785
,
ENST00000316754
PRO
Q9H4E5
Pharos - Targets
Q9H4E5
HMDB Protein
HMDBP08552
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00401 WASL
4
N-WASP [cytosol]
(R-HSA-201873)
p-Y256-WASL [cytosol]
(R-HSA-2197672)
WASL [plasma membrane]
(R-HSA-203010)
WASL [endocytic vesicle membrane]
(R-HSA-535012)
0.718
6
UniProt:Q13177 PAK2
11
PAK2(1-524) [plasma membrane]
(R-HSA-164946)
p-S141,T402-PAK2 [plasma membrane]
(R-HSA-5096524)
p-Y130,S141,T402-PAK2 [cytosol]
(R-HSA-5218705)
K48polyUb-p-T402-PAK-2p43 [cytosol]
(R-HSA-3095873)
p-T402-PAK2(213-524) [nucleoplasm]
(R-HSA-211709)
p-T402-PAK2(213-524) [cytosol]
(R-HSA-211654)
p-5S-PAK2(2-212) [cytosol]
(R-HSA-211588)
p-S141,T402-PAK2 [cytosol]
(R-HSA-399824)
PAK2 [cytosol]
(R-HSA-211604)
p-5S-PAK2 [cytosol]
(R-HSA-211609)
PAK2(213-524) [cytosol]
(R-HSA-211653)
0.718
6
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:O14503 BHLHE40
1
BHLHE40 [nucleoplasm]
(R-HSA-879741)
0.556
3
UniProt:Q13153 PAK1
6
Active PAK1 [cytosol]
(R-HSA-8964622)
p-S144-PAK1 [cytosol]
(R-HSA-451339)
PAK1 [plasma membrane]
(R-HSA-3928409)
p-S144,T423-PAK1 [plasma membrane]
(R-HSA-3928472)
PAK1 [cytosol]
(R-HSA-162629)
p-S144,T423-PAK1 [cytosol]
(R-HSA-399819)
0.556
3
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