Reactome | RHOT1 [mitochondrial outer membrane]

RHOT1 [mitochondrial outer membrane]

Stable Identifier

R-HSA-3006728

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Mitochondrial Rho GTPase 1, MIRO1_HUMAN

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External Reference Information

External Reference

UniProt:Q8IXI2 RHOT1

Gene Names

RHOT1, ARHT1

Chain

chain:1-618

Reference Genes

BioGPS Gene:55288 RHOT1

COSMIC (genes):RHOT1 RHOT1

CTD Gene:55288 RHOT1

dbSNP Gene:55288 RHOT1

ENSEMBL:ENSG00000126858.19 RHOT1

HGNC:21168 RHOT1

KEGG Gene (Homo sapiens):55288 RHOT1

Monarch:55288 RHOT1

NCBI Gene:55288 RHOT1

OMIM:613888 RHOT1

UCSC:Q8IXI2 RHOT1

Reference Transcript

Other Identifiers

0005290039

11740379_s_at

11756578_a_at

16833082

218323_PM_at

218323_at

222148_PM_s_at

222148_s_at

224044_PM_at

224044_at

3503428

3503429

3503431

3503433

3717540

3717541

3717542

3717545

3717548

3717549

3717550

3717551

3717555

3717556

3717558

3717559

3717560

3717561

3717562

3717563

3717564

3717566

3717567

3717568

3717570

3717572

3717576

3717577

3717578

3717579

3717580

3717588

3717589

3717590

3717591

3717592

3717593

3717594

3925288

3925290

55288

8006345

91428_at

A_14_P123761

A_23_P433204

A_24_P59765

A_33_P3326530

A_33_P3668049

GE55955

GO:0000166

GO:0003674

GO:0003924

GO:0005509

GO:0005515

GO:0005525

GO:0005622

GO:0005737

GO:0005739

GO:0005741

GO:0007005

GO:0007018

GO:0007264

GO:0010821

GO:0012501

GO:0016020

GO:0016021

GO:0016787

GO:0019725

GO:0023052

GO:0031307

GO:0043226

GO:0046872

GO:0047497

GO:0061024

GO:0097345

HMNXSV003001605

HMNXSV003029455

HMNXSV003031160

Hs.14202.2.S1_3p_a_at

ILMN_1678504

ILMN_1731484

ILMN_2338480

PH_hs_0001355

PH_hs_0038716

TC17000373.hg

g12053352_3p_at

g8922837_3p_at

Participates

as a component of

as a member of

MOM proteins [mitochondrial outer membrane] (Homo sapiens)

Other forms of this molecule

PolyUb-RHOT1 [mitochondrial outer membrane]

Inferred To

RHOT1 [mitochondrial outer membrane] (Bos taurus)

RHOT1 [mitochondrial outer membrane] (Caenorhabditis elegans)

RHOT1 [mitochondrial outer membrane] (Canis familiaris)

RHOT1 [mitochondrial outer membrane] (Danio rerio)

RHOT1 [mitochondrial outer membrane] (Drosophila melanogaster)

RHOT1 [mitochondrial outer membrane] (Gallus gallus)

RHOT1 [mitochondrial outer membrane] (Mus musculus)

RHOT1 [mitochondrial outer membrane] (Saccharomyces cerevisiae)

RHOT1 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

RHOT1 [mitochondrial outer membrane] (Sus scrofa)

rhot1 [mitochondrial outer membrane] (Xenopus tropicalis)

Rhot1 [mitochondrial outer membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001275684.1, NP_001275687.1, NP_001275683.1, NP_001028738.1, NP_001028739.2, NP_001028740.1, NP_060777.3

OpenTargets

ENSG00000126858

HPA

ENSG00000126858-RHOT1

GeneCards

Q8IXI2

Ensembl

ENSP00000334724, ENSP00000378184, ENST00000581094, ENSP00000462669, ENST00000545287, ENST00000358365, ENST00000333942, ENSP00000464094, ENST00000581031, ENSP00000439737, ENSG00000126858, ENSP00000351132, ENST00000394692

PRO

Q8IXI2

Pharos - Targets

Q8IXI2

PDB

5KSP, 5KTY, 5KSO, 5KSY, 5KSZ, 6D71, 5KU1

HMDB Protein

HMDBP10639

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BXM7 PINK1	4	PINK1 [mitochondrial outer membrane] (R-HSA-5205653) PINK1 [mitochondrial intermembrane space] (R-HSA-5205671) PINK1 [cytosol] (R-HSA-5205637) PINK1(111-581) [mitochondrial intermembrane space] (R-HSA-5205628)	0.524	3
UniProt:O60260 PRKN	3	polyUb-PARK2 [cytosol] (R-HSA-5689094) p-S9-PRKN [cytosol] (R-HSA-9793481) PRKN [cytosol] (R-HSA-201579)	0.524	3