Reactome | RHOT2 [mitochondrial outer membrane]

RHOT2 [mitochondrial outer membrane]

Stable Identifier

R-HSA-3006730

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial outer membrane

Synonyms

Mitochondrial Rho GTPase 2, MIRO2_HUMAN

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External Reference Information

External Reference

UniProt:Q8IXI1 RHOT2

Gene Names

RHOT2, ARHT2, C16orf39

Chain

chain:1-618

Reference Genes

BioGPS Gene:89941 RHOT2

COSMIC (genes):RHOT2 RHOT2

CTD Gene:89941 RHOT2

dbSNP Gene:89941 RHOT2

ENSEMBL:ENSG00000140983 RHOT2

HGNC:21169 RHOT2

Monarch:89941 RHOT2

NCBI Gene:89941 RHOT2

OMIM:613889 RHOT2

UCSC:Q8IXI1 RHOT2

Reference Transcript

RefSeq:NM_138769.2 RHOT2

Other Identifiers

11737635_a_at

11744386_a_at

16814455

221789_3p_x_at

221789_PM_x_at

221789_x_at

222131_3p_x_at

222131_PM_x_at

222131_x_at

3643230

3643231

3643232

3643233

3643234

3643235

3643236

3643237

3643238

3643239

3643240

3643241

3643242

3643243

3643244

3643245

3643246

3643247

3643248

3643249

3643250

3643251

3643252

3643253

3643254

3643255

3643256

3643257

3643258

3643259

3643260

3643261

3643262

3643263

3643264

3643265

3643266

3643267

3643268

3643269

3643270

3643271

4890925_3p_x_at

65770_PM_at

65770_at

7991989

89941

A_14_P120738

A_23_P15067

A_33_P3393350

GE57005

GE63276

GO:0000166

GO:0003824

GO:0003924

GO:0005509

GO:0005515

GO:0005525

GO:0005739

GO:0005741

GO:0007005

GO:0007018

GO:0007264

GO:0016020

GO:0016787

GO:0019725

GO:0043226

GO:0046872

GO:0047497

GO:0061024

GO:0097345

HMNXSV003031803

Hs.21497.0.S1_3p_s_at

Hs.21497.1.S1_3p_s_at

Hs.21497.1.S1_3p_x_at

ILMN_1669310

PH_hs_0025948

TC16000024.hg

Participates

as a component of

Inferred To

RHOT1 [mitochondrial outer membrane] (Caenorhabditis elegans)

RHOT1 [mitochondrial outer membrane] (Dictyostelium discoideum)

RHOT1 [mitochondrial outer membrane] (Drosophila melanogaster)

RHOT1 [mitochondrial outer membrane] (Saccharomyces cerevisiae)

RHOT1 [mitochondrial outer membrane] (Schizosaccharomyces pombe)

RHOT2 [mitochondrial outer membrane] (Bos taurus)

RHOT2 [mitochondrial outer membrane] (Danio rerio)

RHOT2 [mitochondrial outer membrane] (Gallus gallus)

RHOT2 [mitochondrial outer membrane] (Mus musculus)

RHOT2 [mitochondrial outer membrane] (Rattus norvegicus)

RHOT2 [mitochondrial outer membrane] (Sus scrofa)

RHOT2 [mitochondrial outer membrane] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSP00000321971, ENST00000315082

OpenTargets

ENSG00000140983

HPA

ENSG00000140983-RHOT2

PRO

Q8IXI1

Pharos - Targets

Q8IXI1

PDB

5KUT

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q8N661 TMEM86B	1	TMEM86B [endoplasmic reticulum membrane] (R-HSA-8874443)	0.556	3
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.527	2
UniProt:O00410 IPO5	1	IPO5 [nucleoplasm] (R-HSA-192675)	0.527	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	6

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