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NET1 [cytosol]
Stable Identifier
R-HSA-3006799
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Neuroepithelial cell-transforming gene 1 protein, ARHG8_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
p75NTR indirectly activates RAC and Cdc42 via a guanyl-nucleotide exchange factor (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
NET1 [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (12/13) signalling events (Homo sapiens)
GEFs activate RhoA,B,C (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
NET1 [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase cycle (Homo sapiens)
RHOA GTPase cycle (Homo sapiens)
RHOA GEFs activate RHOA (Homo sapiens)
RHOA GEFs [cytosol] (Homo sapiens)
NET1 [cytosol] (Homo sapiens)
RHOB GTPase cycle (Homo sapiens)
RHOB GEFs activate RHOB (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
NET1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z628 NET1
Gene Names
NET1, ARHGEF8
Chain
chain:1-596
Reference Genes
BioGPS Gene:10276 NET1
COSMIC (genes):NET1 NET1
CTD Gene:10276 NET1
dbSNP Gene:10276 NET1
ENSEMBL:ENSG00000173848 NET1
HGNC:14592 NET1
KEGG:hsa:10276 NET1
Monarch:10276 NET1
NCBI Gene:10276 NET1
OMIM:606450 NET1
UCSC:Q7Z628 NET1
Reference Transcript
RefSeq:NM_005863.4 NET1
RefSeq:NM_001047160.2 NET1
Other Identifiers
10276
11718576_s_at
11718577_s_at
11749155_a_at
16702047
201829_PM_at
201829_at
201830_PM_s_at
201830_s_at
3233183
3233184
3233185
3233188
3233190
3233192
3233193
3233194
3233198
3233200
3233202
3233203
3233204
3233205
3233206
3233207
3233208
3233209
3233210
3233211
3233212
3233213
3233214
3233216
3233217
3233218
3233219
3233220
3233221
33894_at
7925954
A_23_P83931
A_33_P3210085
GE55187
GO:0001558
GO:0005085
GO:0005515
GO:0005634
GO:0005737
GO:0005829
GO:0007165
GO:0035025
GO:0035556
GO:0043065
GO:0043226
GO:0043547
GO:0048870
GO:0051056
GO:0051451
GO:0070301
GO:0071479
GO:0098772
HMNXSV003030534
Hs.25155.0.S2_3p_at
ILMN_1758311
ILMN_2267535
ILMN_2359345
PH_hs_0002211
TC10000047.hg
TC10001855.hg
U02081_at
g5031938_3p_a_at
Participates
as a member of
RHOA GEFs [cytosol] (Homo sapiens)
RHOB GEFs [cytosol] (Homo sapiens)
GEFs [cytosol] (Homo sapiens)
Inferred To
net1 [cytosol]
(Xenopus tropicalis)
Net1 [cytosol]
(Mus musculus)
Net1 [cytosol]
(Rattus norvegicus)
NET1 [cytosol]
(Bos taurus)
NET1 [cytosol]
(Canis familiaris)
NET1 [cytosol]
(Gallus gallus)
NET1 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001040625.1
,
NP_005854.2
ENSEMBL
ENSP00000369717
,
ENSP00000347134
,
ENST00000380359
,
ENST00000355029
OpenTargets
ENSG00000173848
HPA
ENSG00000173848-NET1
PRO
Q7Z628
Pharos - Targets
Q7Z628
HMDB Protein
HMDBP08311
PDB
3EO2
,
4XH9
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q14160 SCRIB
1
SCRIB [cytosol]
(R-HSA-4608858)
0.609
2
UniProt:Q12959 DLG1
4
DLG1 [endoplasmic reticulum membrane]
(R-HSA-9610593)
DLG1 [transport vesicle membrane]
(R-HSA-9610631)
DLG1 [cytosol]
(R-HSA-416332)
DLG1 [plasma membrane]
(R-HSA-375977)
0.609
5
UniProt:O43639 NCK2
1
NCK2 [cytosol]
(R-HSA-204885)
0.556
3
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