Reactome | PSIP1 [nucleoplasm]

PSIP1 [nucleoplasm]

Stable Identifier

R-HSA-3008841

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PC4 and SFRS1-interacting protein, LEDGF, PSIP1_HUMAN

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External Reference Information

External Reference

UniProt:O75475 PSIP1

Gene Names

PSIP1, DFS70, LEDGF, PSIP2

Chain

chain:1-530

Reference Genes

BioGPS Gene:11168 PSIP1

COSMIC (genes):PSIP1 PSIP1

CTD Gene:11168 PSIP1

dbSNP Gene:11168 PSIP1

ENSEMBL:ENSG00000164985 PSIP1

HGNC:9527 PSIP1

KEGG:hsa:11168 PSIP1

Monarch:11168 PSIP1

NCBI Gene:11168 PSIP1

OMIM:603620 PSIP1

UCSC:O75475 PSIP1

Reference Transcript

Other Identifiers

11168

11734600_a_at

11742933_a_at

11761869_at

1554933_PM_at

1554933_at

17092615

205961_PM_s_at

205961_s_at

209337_PM_at

209337_at

210758_PM_at

210758_at

3163066

3199789

3199791

3199792

3199793

3199796

3199798

3199799

3199800

3199801

3199802

3199803

3199804

3199805

3199806

3199807

3199808

3199809

3199810

3199812

3199814

3199815

3199816

3199817

3199818

3199820

3199822

3199823

3199824

3199825

3199826

3199827

3199828

37622_r_at

39243_s_at

70817_r_at

8160238

8180299

A_23_P256384

A_24_P929106

A_24_P98371

A_32_P22702

A_32_P32043

A_33_P3226605

A_33_P3226610

GE54580

GO:0000395

GO:0000791

GO:0000792

GO:0003677

GO:0003682

GO:0003713

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005829

GO:0006325

GO:0006338

GO:0006355

GO:0006979

GO:0009408

GO:0034399

GO:0043226

GO:0045944

GO:0060090

GO:0065003

GO:0097100

GO:0140110

GO:0140297

HMNXSV003010046

HMNXSV003042644

Hs2.375073.1.S1_3p_x_at

ILMN_1679319

ILMN_1788701

PH_hs_0023938

TC09000925.hg

U94319_at

g3283351_3p_at

g4050033_3p_at

g4758869_3p_s_at

Participates

as a component of

as an input of

Other forms of this molecule

PSIP1 [cytosol]

Inferred To

Psip1 [nucleoplasm] (Mus musculus)

Psip1 [nucleoplasm] (Rattus norvegicus)

Jasper [nucleoplasm] (Drosophila melanogaster)

PSIP1 [nucleoplasm] (Bos taurus)

PSIP1 [nucleoplasm] (Sus scrofa)

Cross References

OpenTargets

ENSG00000164985

ENSEMBL

ENST00000380716, ENST00000380738, ENST00000397519, ENST00000380733, ENSP00000380653, ENST00000380715, ENSP00000370114, ENSP00000370109, ENSP00000370092, ENSP00000370091

HPA

ENSG00000164985-PSIP1

PRO

O75475

Pharos - Targets

O75475

GlyGen

O75475

PDB

7PEL, 2B4J, 3ZEH, 6EMP, 3F9K, 6EMQ, 5N88, 3HPG, 8PC5, 8PC6, 1Z9E, 6EMO, 8PEO, 7OUG, 2M16, 6ZV0, 3HPH, 8PEP, 7OUF, 2MSR, 3U88, 6EMR, 2MTN, 5YI9, 6TVM, 4FU6, 8CBQ, 5OYM, 7OUH, 2N3A, 7Z1Z, 6S01, 8CBN, 6TRJ

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99708 RBBP8	4	p-S327,T847-RBBP8 [nucleoplasm] (R-HSA-5684083) RBBP8 [nucleoplasm] (R-HSA-912399) Ac-K-RBBP8 [nucleoplasm] (R-HSA-5685955) p-S327,T847,T859-RBBP8 [nucleoplasm] (R-HSA-5684138)	0.602	4
UniProt:Q03164 KMT2A	6	KMT2A [cytosol] (R-HSA-9818584) KMT2A(2719-3969) [cytosol] (R-HSA-9818590) KMT2A(1-2718) [cytosol] (R-HSA-9818597) KMT2A [nucleoplasm] (R-HSA-1183223) KMT2A(1-2718) [nucleoplasm] (R-HSA-9818591) KMT2A(2719-3969) [nucleoplasm] (R-HSA-9818593)	0.544	2