Reactome | PPP2R5D [nucleoplasm]

PPP2R5D [nucleoplasm]

Stable Identifier

R-HSA-3008956

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform, 2A5D_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14738 PPP2R5D

Gene Names

PPP2R5D

Chain

chain:1-602

Reference Genes

BioGPS Gene:5528 PPP2R5D

COSMIC (genes):PPP2R5D PPP2R5D

CTD Gene:5528 PPP2R5D

dbSNP Gene:5528 PPP2R5D

ENSEMBL:ENSG00000112640 PPP2R5D

HGNC:9312 PPP2R5D

KEGG:hsa:5528 PPP2R5D

Monarch:5528 PPP2R5D

NCBI Gene:5528 PPP2R5D

OMIM:601646 PPP2R5D

UCSC:Q14738 PPP2R5D

Reference Transcript

Other Identifiers

11719794_a_at

11719795_a_at

11719796_x_at

11749173_a_at

11752412_a_at

17008728

202513_PM_s_at

202513_s_at

211159_PM_s_at

211159_s_at

2907539

2907540

2907541

2907545

2907546

2907547

2907548

2907549

2907550

2907552

2907553

2907554

2907555

2907556

2907557

2907558

2907559

2907560

2907561

2907562

2907563

2907564

2907565

2907566

2907567

2907569

39068_at

5528

8119627

A_14_P110643

A_24_P294931

GE57792

GO:0000159

GO:0003824

GO:0004721

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006470

GO:0007165

GO:0007399

GO:0016787

GO:0019888

GO:0035307

GO:0043226

GO:0048856

GO:0072542

GO:0098772

GO:0140096

HMNXSV003044004

ILMN_1699384

ILMN_1780940

ILMN_2359887

L76702_at

PH_hs_0006503

TC06000591.hg

g2189948_3p_a_at

g5453953_3p_a_at

Participates

as a component of

PP2A-ABdeltaC complex [nucleoplasm] (Homo sapiens)

Other forms of this molecule

PPP2R5D [cytosol]

Inferred To

par2 [nucleoplasm] (Schizosaccharomyces pombe)

PPP2R5D [nucleoplasm] (Bos taurus)

PPP2R5D [nucleoplasm] (Canis familiaris)

PPP2R5D [nucleoplasm] (Sus scrofa)

Ppp2r5d [nucleoplasm] (Mus musculus)

Ppp2r5d [nucleoplasm] (Rattus norvegicus)

RTS1 [nucleoplasm] (Saccharomyces cerevisiae)

ppp2r5d [nucleoplasm] (Danio rerio)

psrA [nucleoplasm] (Dictyostelium discoideum)

pptr-2 [nucleoplasm] (Caenorhabditis elegans)

wrd [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006236.1, NP_851308.1, NP_851307.1, NP_001257405.1

ENSEMBL

ENSP00000417963, ENST00000461010, ENSP00000377669, ENSG00000112640, ENST00000485511, ENSP00000420674, ENST00000394110

OpenTargets

ENSG00000112640

GeneCards

PPP2R5D

HPA

ENSG00000112640-PPP2R5D

PRO

Q14738

Pharos - Targets

Q14738

GlyGen

Q14738

Orphanet

PPP2R5D

PDB

8U89, 8U1X

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P67775 PPP2CA	4	PPP2CA [cytosol] (R-HSA-165971) PPP2CA [nucleoplasm] (R-HSA-165978) p-Y307-PPP2CA [cytosol] (R-HSA-8857939) MeL-PPP2CA [nucleoplasm] (R-HSA-8857791)	0.864	8
UniProt:Q5FBB7 SGO1	3	SGOL1 [cytosol] (R-HSA-376227) SGO1 [nucleoplasm] (R-HSA-2468161) p-S-SGO1 [nucleoplasm] (R-HSA-9929718)	0.667	4
UniProt:P30307 CDC25C	8	p-S198-CDC25C [nucleoplasm] (R-HSA-156668) CDC25C [cytosol] (R-HSA-157879) p-S198-CDC25C [cytosol] (R-HSA-8981697) CDC25C [nucleoplasm] (R-HSA-69741) p-S216-CDC25C [nucleoplasm] (R-HSA-156496) p-S216-CDC25C [cytosol] (R-HSA-75003) p-S191-CDC25C [nucleoplasm] (R-HSA-6802968) p-T48,T67,S122,T130,S168,S214-CDC25C [cytosol] (R-HSA-8863654)	0.589	2
UniProt:O08785 Clock	6	p-T451,T461-Clock [nucleoplasm] (R-MMU-9920668) Clock [cytosol] (R-MMU-508720) p-T451,T461-Clock [cytosol] (R-MMU-9920658) p-S-Clock [nucleoplasm] (R-MMU-508670) p-T451,T461,S440,S441,S446-Clock [nucleoplasm] (R-MMU-9920662) p-S,T451,T461,S440,S441,S446-Clock [nucleoplasm] (R-MMU-9927976)	0.508	2