Reactome | p-T38-ETS1 [nucleoplasm]

p-T38-ETS1 [nucleoplasm]

Stable Identifier

R-HSA-3132720

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:P14921 ETS1

Expand all

External Reference Information

External Reference

UniProt:P14921 ETS1

Gene Names

ETS1, EWSR2

Chain

chain:1-441

Reference Genes

COSMIC (genes):ETS1 ETS1

dbSNP Gene:2113 ETS1

ENSEMBL:ENSG00000134954 ETS1

Participates

as an input of

Phosphorylated ETS1 binds p16INK4A promoter (Homo sapiens)

as a component of

p-T38-ETS1:CDKN2A gene [nucleoplasm] (Homo sapiens)

as a member of

p-T38-ETS1/ p-T72-ETS2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

ETS1 [nucleoplasm]

Inferred To

phospho-p-T38-ETS1 [nucleoplasm] (Gallus gallus)

phospho-Ets1 [nucleoplasm] (Mus musculus)

phospho-Ets1 [nucleoplasm] (Rattus norvegicus)

phospho-ETS1 [nucleoplasm] (Bos taurus)

phospho-ETS1 [nucleoplasm] (Canis familiaris)

phospho-ETS1 [nucleoplasm] (Sus scrofa)

phospho-ets2 [nucleoplasm] (Danio rerio)

phospho-ets1 [nucleoplasm] (Xenopus tropicalis)

phospho-pnt [nucleoplasm] (Drosophila melanogaster)

Modified Residues

Name

O-phospho-L-threonine at 38

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q05519 SRSF11	1	SRSF11 [nucleoplasm] (R-HSA-72058)	0.573	2
UniProt:P19838 NFKB1	8	3xUb-p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451619) p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451611) NFKB1(1-968) [cytosol] (R-HSA-451607) NFKB1(1-433) [nucleoplasm] (R-HSA-177655) NFKB1(1-433) [cytosol] (R-HSA-168168) NFKB1(1-968) [specific granule lumen] (R-HSA-6799557) NFKB1(1-968) [extracellular region] (R-HSA-6806304) NFKB1(1-968) [secretory granule lumen] (R-HSA-6801004)	0.536	2
UniProt:P51531 SMARCA2	1	SMARCA2 [nucleoplasm] (R-HSA-389256)	0.536	2
UniProt:P28482 MAPK1	18	p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) MAPK1 [cytosol] (R-HSA-59282) MAPK1 [nucleoplasm] (R-HSA-199960) p-T185-MAPK1 [cytosol] (R-HSA-9635773) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) MAPK1 [azurophil granule lumen] (R-HSA-6799225) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293)	0.528	3
UniProt:P78527 PRKDC	4	PRKDC [nucleoplasm] (R-HSA-62161) p-T2609,S2612,T2638,T2647-PRKDC [nucleoplasm] (R-HSA-76302) PRKDC [cytosol] (R-HSA-3134816) K48polyUb-PRKDC [cytosol] (R-HSA-8938766)	0.525	2
UniProt:Q9BQA9 CYBC1			0.524	3
UniProt:Q4LE39 ARID4B	1	ARID4B [nucleoplasm] (R-HSA-2976647)	0.524	2
UniProt:O60841 EIF5B	1	EIF5B [cytosol] (R-HSA-72501)	0.524	2
UniProt:P05412 JUN	4	JUN [nucleoplasm] (R-HSA-450250) p-S63,S73-JUN [nucleoplasm] (R-HSA-450237) JUN [cytosol] (R-HSA-168194) p-S63,S73-JUN [cytosol] (R-HSA-8868682)	0.524	3
UniProt:P23497 SP100	3	polySUMO2-K297-SP100 [nucleoplasm] (R-HSA-3000454) monoSUMO1-K297-SP100 [nucleoplasm] (R-HSA-3000382) SP100 [nucleoplasm] (R-HSA-1031705)	0.508	4
UniProt:P17542 TAL1	1	TAL1 [nucleoplasm] (R-HSA-8956511)	0.499	2
UniProt:P14921 ETS1	2	ETS1 [nucleoplasm] (R-HSA-1629809) p-T38-ETS1 [nucleoplasm] (R-HSA-3132720)	0.499	2
UniProt:P31314 TLX1			0.463	3
UniProt:O43711 TLX3			0.463	3

Cite Us!