Reactome | BANP [nucleoplasm]

BANP [nucleoplasm]

Stable Identifier

R-HSA-3221973

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein BANP, BEN domain-containing protein 1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein, BEND1, SMAR1

Locations in the PathwayBrowser for interactor UniProt:Q8TCE9 PPL13

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional Regulation by TP53 (Homo sapiens)
      - Regulation of TP53 Activity (Homo sapiens)
        
        Regulation of TP53 Activity through Association with Co-factors (Homo sapiens)
        
        BANP binds TP53 (Homo sapiens)
        
        BANP [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8N9N5 BANP

Gene Names

BANP, BEND1, SMAR1

Chain

chain:1-519

Reference Genes

BioGPS Gene:54971 BANP

COSMIC (genes):BANP BANP

CTD Gene:54971 BANP

dbSNP Gene:54971 BANP

ENSEMBL:ENSG00000172530 BANP

ENSEMBL_homo_sapiens_GENE:ENSG00000172530.22 BANP

HGNC:13450 BANP

KEGG Gene (Homo sapiens):54971 BANP

Monarch:54971 BANP

NCBI Gene:54971 BANP

OMIM:611564 BANP

UCSC:Q8N9N5 BANP

Reference Transcript

Other Identifiers

11739908_a_at

11740935_s_at

11747303_x_at

11749222_s_at

11753909_x_at

219966_PM_x_at

219966_x_at

228928_PM_x_at

228928_x_at

233186_PM_s_at

233186_s_at

3651704

3651708

3651714

3655240

3655270

3655275

3655278

3655279

3673094

3673099

3673100

3673101

3673104

3673105

3673117

3673120

3673131

3673138

3673140

3673144

3673148

3673156

3673167

3673175

3673176

3673177

3673178

50761_at

54971

73242_at

7997755

A_14_P121000

A_23_P22263

A_23_P251765

A_33_P3236272

GE56815

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0006325

GO:0007049

GO:0016604

GO:0030163

GO:0034504

GO:0042177

GO:0042802

GO:0043226

HMNXSV003018649

Hs.194637.2.S1_3p_a_at

ILMN_1663631

ILMN_1680685

ILMN_1701216

PH_hs_0026221

Participates

as a component of

TP53:BANP [nucleoplasm] (Homo sapiens)

as an input of

BANP binds TP53 (Homo sapiens)

Inferred To

BANP [nucleoplasm] (Bos taurus)

BANP [nucleoplasm] (Canis familiaris)

BANP [nucleoplasm] (Gallus gallus)

BANP [nucleoplasm] (Rattus norvegicus)

BANP [nucleoplasm] (Sus scrofa)

banp [nucleoplasm] (Danio rerio)

banp [nucleoplasm] (Xenopus tropicalis)

Banp [nucleoplasm] (Mus musculus)

Cross References

RefSeq

NP_001167012.1, NP_060339.2, NP_001167014.1, NP_001167011.1, NP_524576.2, NP_001167013.1, NP_001167010.1

OpenTargets

ENSG00000172530

HPA

ENSG00000172530-BANP

GeneCards

Q8N9N5

Ensembl

ENSG00000172530, ENSP00000286122, ENST00000626016, ENST00000393207, ENSP00000432508, ENST00000393208, ENSP00000376902, ENST00000355022, ENSP00000444352, ENSP00000376903, ENSP00000347125, ENST00000286122, ENST00000479780, ENSP00000487304, ENST00000538234

PRO

Q8N9N5

Pharos - Targets

Q8N9N5

PDB

8HTX, 7YUK, 7YUG

HMDB Protein

HMDBP12789

Interactors (74)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.743	7
UniProt:Q96BD5 PHF21A	1	PHF21A [nucleoplasm] (R-HSA-996754)	0.666	4
UniProt:Q96JM7 LMBL3			0.666	4
UniProt:Q12815 TROAP			0.666	4
UniProt:Q96BZ8 LENG1	1	LENG1 [nucleoplasm] (R-HSA-9769590)	0.666	4
UniProt:Q14511 CASL			0.666	4
UniProt:Q6P1W5 CA094			0.666	4
UniProt:P22105 TNXB	1	TNXB [extracellular region] (R-HSA-2672026)	0.666	4
UniProt:Q13557 CAMK2D	5	p-T287-CAMK2D [plasma membrane] (R-HSA-432794) p-T287-CAMK2D [nucleoplasm] (R-HSA-444785) p-T287-CAMK2D [endocytic vesicle membrane] (R-HSA-417002) CAMK2D [cytosol] (R-HSA-9611357) p-T287-CAMK2D [cytosol] (R-HSA-445370)	0.666	4
UniProt:Q02086 SP2			0.666	4
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.666	4
UniProt:Q9BX82 ZNF471	1	ZNF471 [nucleoplasm] (R-HSA-1247864)	0.573	5
UniProt:Q96MN9 ZN488			0.556	3
UniProt:Q8TCE9 PPL13			0.556	3
UniProt:Q8NEG0 GAR6			0.556	3
UniProt:Q8WUT1 Q8WUT1			0.556	3
UniProt:Q9BVQ0 Q9BVQ0			0.556	3
UniProt:Q8WV93 AFG1L			0.556	3
UniProt:Q9HD64 XAGE1			0.556	3
IntAct:EBI-10268368 128872			0.556	3
UniProt:Q9P0T4 ZN581			0.556	3
UniProt:Q969S9 GFM2	1	GFM2 [mitochondrial matrix] (R-HSA-5389858)	0.556	3
UniProt:O15427 SLC16A3	1	SLC16A3 [plasma membrane] (R-HSA-204390)	0.556	3
UniProt:Q08AM8 Q08AM8			0.556	3
UniProt:CCDC26 A0A024R9H7			0.556	3
UniProt:Q86YD7 F90A1			0.556	3
UniProt:Q8IYR0 CF206			0.556	3
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.556	3
UniProt:Q6P5X5 CV039			0.556	3
UniProt:P25791 LMO2	1	LMO2 [nucleoplasm] (R-HSA-8956513)	0.556	3
UniProt:O94842 TOX4			0.556	3
UniProt:P30405 PPIF			0.556	3
UniProt:Q93062 RBPMS			0.556	3
UniProt:O43741 PRKAB2	2	PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [nucleoplasm] (R-HSA-164096)	0.556	3
UniProt:P23284 PPIB	2	PPIB [endoplasmic reticulum lumen] (R-HSA-1980262) PPIB [cytosol] (R-HSA-9728770)	0.556	3
UniProt:Q53FD0 ZC21C			0.556	3
UniProt:P61968 LMO4			0.556	3
UniProt:W5XKT8 SACA6			0.556	3
UniProt:Q9Y333 LSM2	2	LSM2 [nucleoplasm] (R-HSA-71894) LSM2 [cytosol] (R-HSA-429849)	0.556	3
UniProt:P22557 ALAS2	1	PXLP-K391-ALAS2 [mitochondrial matrix] (R-HSA-1022083)	0.556	3
UniProt:Q6P1L5 F117B			0.556	3
UniProt:Q7Z2X4 PCLI1			0.556	3
UniProt:Q8TEC5 SH3R2			0.556	3
IntAct:EBI-10177803 57573			0.556	3
UniProt:Q13084 MRPL28	1	MRPL28 [mitochondrial inner membrane] (R-HSA-5368246)	0.556	3
UniProt:P14678-2 SNRPB			0.556	3
UniProt:Q5JZY3-3 EPHA10			0.556	3
UniProt:Q8TAP6 CEP76	1	CEP76 [cytosol] (R-HSA-380281)	0.556	3
UniProt:Q53NU3 Q53NU3			0.556	3
UniProt:Q8TAP4 LMO3			0.556	3
UniProt:Q9UL15 BAG5	1	BAG5 [cytosol] (R-HSA-5255453)	0.556	3
UniProt:A2VCK2 DCD2B			0.556	3
IntAct:EBI-10182429 84536			0.556	3
UniProt:Q7Z3K3 POGZ			0.556	5
UniProt:Q9BUZ4 TRAF4			0.556	3
UniProt:Q8WW22-2 DNAJA4			0.556	3
UniProt:Q03692 COL10A1	20	3x4Hyp-3Hyp-GlcGalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173263) GalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173066) 3x4Hyp-3Hyp-GalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173242) 3x4Hyp-GlcGalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173191) GlcGalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173104) 3x4Hyp-GalHyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173168) COL10A1 [endoplasmic reticulum lumen] (R-HSA-2172268) 3x4Hyp-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2172959) 3x4Hyp-3Hyp-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2172964) 3x4Hyp-5Hyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173152) 3x4Hyp-3Hyp-5Hyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173232) 5Hyl-COL10A1 [endoplasmic reticulum lumen] (R-HSA-2173007) 3x4Hyp-5Hyl-COL10A1(19-?) [extracellular region] (R-HSA-2470522) 3x4Hyp-3Hyp-COL10A1(19-?) [extracellular region] (R-HSA-2470521) 3x4Hyp-3Hyp-GlcGalHyl-COL10A1(?-680) [extracellular region] (R-HSA-2470526) GlcGalHyl-COL10A1(?-680) [extracellular region] (R-HSA-2470527) 3x4Hyp-GlcGalHyl-COL10A1(?-680) [extracellular region] (R-HSA-2470524) 3x4Hyp-3Hyp-GlcGalHyl-COL10A1(19-?) [extracellular region] (R-HSA-2470525) 3x4Hyp-GalHyl-COL10A1(19-?) [extracellular region] (R-HSA-2470515) 3x4Hyp-COL10A1(19-?) [extracellular region] (R-HSA-2470512)	0.556	3
UniProt:Q8NF64-2 ZMIZ2			0.556	3
UniProt:Q53S70 Q53S70			0.556	3
UniProt:Q6PIV2 FOXR1			0.556	3
UniProt:Q9BQI9 NRIP2			0.556	3
UniProt:Q14498-3 RBM39			0.556	3
IntAct:EBI-10268393 55015			0.556	3
UniProt:P45877 PPIC			0.556	3
IntAct:EBI-10268355 54954			0.556	3
UniProt:Q13444 ADAM15	1	ADAM15 [plasma membrane] (R-HSA-708329)	0.556	3
UniProt:P11309 PIM1	1	PIM1 [nucleoplasm] (R-HSA-3215094)	0.556	3
UniProt:P62875 POLR2L	2	POLR2L [nucleoplasm] (R-HSA-83715) POLR2L [cytosol] (R-HSA-1964467)	0.556	3
UniProt:Q9H1K1 ISCU	1	ISCU [cytosol] (R-HSA-9771680)	0.556	3
UniProt:Q02750 MAP2K1	20	MAP2K1(9-393) [cytosol] (R-HSA-5211353) MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1 F53S [cytosol] (R-HSA-9652034) MAP2K1 D67N [cytosol] (R-HSA-9652016) MAP2K1 Q56P [cytosol] (R-HSA-9652064) MAP2K1 E203K [cytosol] (R-HSA-9652023) MAP2K1 V60E [cytosol] (R-HSA-9652067) MAP2K1 P124S [cytosol] (R-HSA-9652062) MAP2K1 Y130C [cytosol] (R-HSA-9652101) MAP2K1 C121S [cytosol] (R-HSA-9652013) MAP2K1 G128V [cytosol] (R-HSA-9652047) MAP2K1 F53L [cytosol] (R-HSA-9652031) MAP2K1 K57N [cytosol] (R-HSA-9652050) MAP2K1 K57T [cytosol] (R-HSA-9652052) MAP2K1 F53V [cytosol] (R-HSA-9652038) MAP2K1 D67Y [cytosol] (R-HSA-9652019) MAP2K1 G128D [cytosol] (R-HSA-9652043) MAP2K1 P124L [cytosol] (R-HSA-9652056) MAP2K1 F53Y [cytosol] (R-HSA-9652041) MAP2K1 L42_K57del [cytosol] (R-HSA-9652026)	0.556	3
UniProt:Q96QF0 RAB3IP	1	RAB3IP [cytosol] (R-HSA-5617610)	0.556	3
UniProt:O00233 PSMD9	1	PSMD9 [cytosol] (R-HSA-68810)	0.556	3
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.499	3
UniProt:P29590 PML	5	polySUMO3-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000386) polySUMO2-K65,K160,K490-PML [nucleoplasm] (R-HSA-3000423) monoSUMO1-K65,160,490-PML [nucleoplasm] (R-HSA-3000440) PML [nucleoplasm] (R-HSA-1031706) PML [cytosol] (R-HSA-5624327)	0.463	3

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