Reactome | HOXC8 [nucleoplasm]

HOXC8 [nucleoplasm]

Stable Identifier

R-HSA-3222311

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Homeobox protein Hox-C8, Hox-3A, HOX3A

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P31273 HOXC8

Gene Names

HOXC8, HOX3A

Chain

chain:1-242

Reference Genes

BioGPS Gene:3224 HOXC8

COSMIC (genes):HOXC8 HOXC8

CTD Gene:3224 HOXC8

dbSNP Gene:3224 HOXC8

ENSEMBL:ENSG00000037965 HOXC8

HGNC:5129 HOXC8

KEGG:hsa:3224 HOXC8

Monarch:3224 HOXC8

NCBI Gene:3224 HOXC8

OMIM:142970 HOXC8

UCSC:P31273 HOXC8

Reference Transcript

RefSeq:NM_022658.3 HOXC8

Other Identifiers

11735486_at

11735487_at

16751960

221350_PM_at

221350_at

3224

3416355

3416356

3416357

3416358

3416359

3416361

3416362

3416363

3416364

3416365

3416367

7955869

A_14_P113771

A_23_P398476

A_24_P124558

GE812007

GO:0000122

GO:0000785

GO:0000977

GO:0000981

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005856

GO:0006355

GO:0006357

GO:0009952

GO:0015630

GO:0030154

GO:0030182

GO:0043226

GO:0048705

GO:0140110

GO:1990837

HMNXSV003002767

ILMN_1718285

PH_hs_0032306

TC12000452.hg

g12056968_3p_at

p28211

p33916

Participates

as an input of

as a component of

Inferred To

Hoxc8 [nucleoplasm] (Mus musculus)

hoxc8a [nucleoplasm] (Danio rerio)

HOXC8 [nucleoplasm] (Bos taurus)

HOXC8 [nucleoplasm] (Canis familiaris)

HOXC8 [nucleoplasm] (Gallus gallus)

HOXC8 [nucleoplasm] (Sus scrofa)

hoxc8 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_073149.1

OpenTargets

ENSG00000037965

ENSEMBL

ENSP00000040584, ENST00000040584

HPA

ENSG00000037965-HOXC8

PRO

P31273

Pharos - Targets

P31273

Interactors (96)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15036 SNX17			0.666	9
UniProt:Q3LI66 KRTAP6-2	1	KRTAP6-2 [cytosol] (R-HSA-6810261)	0.556	3
UniProt:Q3LI67 KRTAP6-3	1	KRTAP6-3 [cytosol] (R-HSA-6810281)	0.556	3
UniProt:Q9NX04 AIRIM			0.556	3
UniProt:Q3LI64 KRTAP6-1	1	KRTAP6-1 [cytosol] (R-HSA-6810298)	0.556	3
UniProt:Q92764 KRT35	1	KRT35 [cytosol] (R-HSA-6809595)	0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q5T749 KPRP	1	KPRP [cytosol] (R-HSA-9839614)	0.556	3
UniProt:O76013-2 KRT36			0.556	3
UniProt:Q99471 PFDN5	1	PFDN5 [cytosol] (R-HSA-379548)	0.556	3
UniProt:Q9H2G9 BLZF1	1	BLZF1 [Golgi membrane] (R-HSA-2422372)	0.556	3
UniProt:Q70EL1-9 USP54			0.556	3
UniProt:Q8IWZ5 TRI42			0.556	3
IntAct:EBI-22616457 CCSB ORF ID			0.556	3
UniProt:Q9UBR4-2 LHX3			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q8NI38 IKBD			0.556	3
UniProt:Q58EX7 PLEKHG4	1	PLEKHG4 [cytosol] (R-HSA-9679579)	0.556	3
UniProt:Q9H4Y5 GSTO2	1	GSTO2 [cytosol] (R-HSA-176066)	0.556	3
UniProt:Q3LHN2 KRTAP19-2	1	KRTAP19-2 [cytosol] (R-HSA-6810262)	0.556	3
UniProt:Q07627 KRTAP1-1	1	KRTAP1-1 [cytosol] (R-HSA-6809855)	0.556	3
UniProt:Q9P2M1 LR2BP			0.556	3
UniProt:A6NJ78-4 METTL15			0.556	3
UniProt:O15496 PLA2G10	1	PLA2G10 [extracellular region] (R-HSA-1498793)	0.556	3
UniProt:Q9H5F2 CFA68			0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q8TF47 ZFP90	1	ZFP90 [nucleoplasm] (R-HSA-974988)	0.556	3
IntAct:EBI-22639009 CCSB ORF ID			0.556	3
UniProt:P13807 GYS1	3	p-S-GYS1 [cytosol] (R-HSA-71570) GYS1 [cytosol] (R-HSA-71565) GYS1 R462* [cytosol] (R-HSA-3828056)	0.556	3
UniProt:Q9Y458 TBX22			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:Q9NQX0 PRDM6			0.556	3
UniProt:Q16610 ECM1	2	ECM1 [extracellular region] (R-HSA-8848909) ECM1 [platelet dense granule lumen] (R-HSA-8848880)	0.556	3
UniProt:O75031 HSF2B			0.556	3
UniProt:Q8IUC2 KRTAP8-1	1	KRTAP8-1 [cytosol] (R-HSA-6810288)	0.556	3
UniProt:Q8IUC1 KRTAP11-1	1	KRTAP11-1 [cytosol] (R-HSA-6810294)	0.556	3
UniProt:Q8IUG1 KRTAP1-3	1	KRTAP1-3 [cytosol] (R-HSA-6809866)	0.556	3
UniProt:Q6IA69 NADSYN1	1	NADSYN1 [cytosol] (R-HSA-197231)	0.556	3
UniProt:Q9BYU1 PBX4			0.556	3
UniProt:Q9UDW3 ZMAT5	1	ZMAT5 [nucleoplasm] (R-HSA-6787850)	0.556	3
UniProt:Q9NZC7-5 WWOX			0.556	3
UniProt:Q86TI0 TBC1D1	2	TBC1D1 [cytoplasmic vesicle membrane] (R-HSA-1454718) p-S237-TBC1D1 [cytosol] (R-HSA-1454673)	0.556	3
UniProt:Q49AR9 Q49AR9			0.556	3
IntAct:EBI-22617209 CCSB ORF ID			0.556	3
UniProt:Q5BKX5-3 ACTMAP			0.556	3
UniProt:P78424 PO6F2			0.556	3
UniProt:A2RRN7 A2RRN7			0.556	3
UniProt:Q15654 TRIP6			0.556	3
UniProt:Q9UKT9 IKZF3			0.556	3
UniProt:O95231 VENTX	1	VENTX [nucleoplasm] (R-HSA-8853887)	0.556	3
UniProt:Q9GZV8 PRDM14	1	PRDM14 [nucleoplasm] (R-HSA-1112608)	0.556	3
UniProt:P50458 LHX2	1	LHX2 [nucleoplasm] (R-HSA-9011100)	0.556	3
UniProt:P0DPK4 NOTCH2NLC	1	NOTCH2NLC [extracellular region] (R-HSA-9908932)	0.556	3
UniProt:P31249 HOXD3	1	HOXD3 [nucleoplasm] (R-HSA-5617674)	0.556	3
UniProt:Q5SW96 LDLRAP1	2	LDLRAP1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869097) LDLRAP1 [plasma membrane] (R-HSA-171143)	0.556	8
UniProt:Q96RU7 TRIB3	3	TRIB3 [plasma membrane] (R-HSA-199447) TRIB3 [cytosol] (R-HSA-162411) TRIB3 [nucleoplasm] (R-HSA-9635877)	0.556	3
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q06710 PAX8	1	PAX8 [nucleoplasm] (R-HSA-3968418)	0.556	3
UniProt:Q02548 PAX5	1	PAX5 [nucleoplasm] (R-HSA-158583)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q16633 OBF1			0.556	3
UniProt:Q9BYM8 RBCK1	1	RBCK1 [cytosol] (R-HSA-976018)	0.556	3
UniProt:P59990 KRTAP12-1	1	KRTAP12-1 [cytosol] (R-HSA-6810248)	0.556	3
UniProt:Q63HR2 TENS2			0.556	3
UniProt:Q92997 DVL3	4	pp-DVL3 [cytosol] (R-HSA-3772400) p-DVL3 [cytosol] (R-HSA-201680) DVL3 [cytosol] (R-HSA-201678) ub-DVL3 [cytosol] (R-HSA-4652688)	0.556	3
UniProt:Q8IV28 Q8IV28			0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:P50221 MEOX1			0.556	3
UniProt:Q5VU43-2 PDE4DIP			0.556	3
UniProt:A6NEM1 GG6L9			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:Q86WV8 Q86WV8			0.556	3
UniProt:Q8ND83 SLAI1			0.556	3
UniProt:Q9BSQ5 CCM2			0.556	3
UniProt:Q7L273 KCTD9			0.556	3
UniProt:P49356 FNTB	1	FNTB [cytosol] (R-HSA-2530482)	0.556	3
UniProt:P05813 CRBA1			0.556	3
UniProt:Q86Y13 DZIP3	1	DZIP3 [cytosol] (R-HSA-976002)	0.556	3
UniProt:O60806 TBX19			0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q9UBX0 HESX1			0.556	3
UniProt:O95751 LDOC1			0.556	3
UniProt:Q3SY46 KRTAP13-3	1	KRTAP13-3 [cytosol] (R-HSA-6810267)	0.556	3
UniProt:Q13387-4 MAPK8IP2			0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	5
IntAct:EBI-22320186 CCSB ORF ID			0.556	3
UniProt:O76011 KRT34	1	KRT34 [cytosol] (R-HSA-6809608)	0.556	5
UniProt:P40424 PBX1	1	PBX1 [nucleoplasm] (R-HSA-453045)	0.556	3
UniProt:Q8WW24 TEKT4			0.556	3
UniProt:P40425 PBX2			0.556	3
UniProt:Q9UQF2 JIP1			0.527	2
UniProt:Q93062-3 RBPMS			0.488	2

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