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SNX3 [cytosol]
Stable Identifier
R-HSA-3247743
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
SDP3, retromer
Locations in the PathwayBrowser for interactor UniProt:Q96QK1 VPS35
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
WNT ligand biogenesis and trafficking (Homo sapiens)
Retromer associates with WLS (Homo sapiens)
SNX3 [cytosol] (Homo sapiens)
WLS dissociates from retromer (Homo sapiens)
SNX3 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60493 SNX3
Gene Names
SNX3
Chain
initiator methionine:, chain:2-162
Reference Genes
BioGPS Gene:8724 SNX3
COSMIC (genes):SNX3 SNX3
CTD Gene:8724 SNX3
dbSNP Gene:8724 SNX3
ENSEMBL:ENSG00000112335 SNX3
ENSEMBL_homo_sapiens_GENE:ENSG00000112335.15 SNX3
HGNC:11174 SNX3
KEGG Gene (Homo sapiens):8724 SNX3
Monarch:8724 SNX3
NCBI Gene:8724 SNX3
OMIM:605930 SNX3
UCSC:O60493 SNX3
Reference Transcript
RefSeq:NM_003795.5 SNX3
RefSeq:NM_001300929.1 SNX3
RefSeq:NM_152827.3 SNX3
Other Identifiers
11715738_s_at
11728533_a_at
11754173_a_at
17022349
18670525
18670526
18670527
18670528
18670529
18670530
18670531
18670532
18670533
200067_PM_x_at
200067_x_at
208781_PM_x_at
210648_PM_x_at
210648_x_at
213545_PM_x_at
213545_x_at
2968244
2968245
2968246
2968247
2968249
2968250
2968257
2968258
2968259
2968260
39360_at
7892770
7893777
7894157
7894771
7895231
7895478
7895544
7896605
8128683
8724
A_23_P42498
A_24_P277807
A_33_P3345796
GE61205
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005768
GO:0005769
GO:0005829
GO:0008289
GO:0009617
GO:0010008
GO:0010314
GO:0010324
GO:0010976
GO:0015031
GO:0016192
GO:0019903
GO:0022615
GO:0023052
GO:0030111
GO:0030136
GO:0030154
GO:0030163
GO:0030904
GO:0031410
GO:0031901
GO:0032009
GO:0032266
GO:0032456
GO:0034499
GO:0035091
GO:0042177
GO:0043226
GO:0045335
GO:0046597
GO:0048856
GO:0050765
GO:0051224
GO:0061024
GO:0070062
GO:0070273
GO:0070676
GO:0080025
GO:1901981
GO:1905394
GO:2000642
HMNXSV003000660
HMNXSV003014364
ILMN_1740180
ILMN_1795557
PH_hs_0001136
TC06001994.hg
g12957159_3p_a_at
g3126978_3p_a_at
Participates
as an input of
Retromer associates with WLS (Homo sapiens)
as a component of
WLS:retromer [early endosome membrane] (Homo sapiens)
WLS:retromer [Golgi membrane] (Homo sapiens)
as an output of
WLS dissociates from retromer (Homo sapiens)
Other forms of this molecule
PolyUb-SNX3 [endosome membrane]
SNX3 [endosome membrane]
Inferred To
snx3 [cytosol]
(Xenopus tropicalis)
snx-3 [cytosol]
(Caenorhabditis elegans)
Snx3 [cytosol]
(Drosophila melanogaster)
SNX3 [cytosol]
(Bos taurus)
SNX3 [cytosol]
(Canis familiaris)
SNX3 [cytosol]
(Dictyostelium discoideum)
SNX3 [cytosol]
(Gallus gallus)
SNX3 [cytosol]
(Mus musculus)
SNX3 [cytosol]
(Rattus norvegicus)
SNX3 [cytosol]
(Saccharomyces cerevisiae)
SNX3 [cytosol]
(Schizosaccharomyces pombe)
SNX3 [cytosol]
(Sus scrofa)
Cross References
RefSeq
NP_001287858.1
,
NP_690040.1
,
NP_003786.1
OpenTargets
ENSG00000112335
HPA
ENSG00000112335-SNX3
GeneCards
O60493
Ensembl
ENST00000426155
,
ENST00000230085
,
ENSP00000357975
,
ENSP00000296991
,
ENST00000368979
,
ENSP00000230085
,
ENSG00000112335
,
ENST00000349379
,
ENSP00000401779
PRO
O60493
Pharos - Targets
O60493
PDB
5F0P
,
5F0L
,
7BLO
,
2YPS
,
2MXC
,
5F0J
,
5F0M
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q15041 AR6P1
0.556
3
UniProt:Q9NS64 RPRM
0.556
3
UniProt:Q96QK1 VPS35
1
VPS35 [cytosol]
(R-HSA-3247740)
0.527
3
UniProt:Q9H8J5 MANS1
0.527
2
UniProt:P59536 TAS2R41
1
TAS2R41 [plasma membrane]
(R-HSA-3299622)
0.527
2
UniProt:P43005 SLC1A1
4
SLC1A1 I395del [plasma membrane]
(R-HSA-5625023)
SLC1A1 84kb_del [plasma membrane]
(R-HSA-5625040)
SLC1A1 R445W [plasma membrane]
(R-HSA-5625045)
SLC1A1 [plasma membrane]
(R-HSA-210414)
0.527
2
UniProt:Q9BWG6 SCNM1
0.527
2
UniProt:P04798 CYP1A1
1
CYP1A1 [endoplasmic reticulum membrane]
(R-HSA-52623)
0.527
2
UniProt:Q8WVK2 SNRNP27
1
SNRNP27 [nucleoplasm]
(R-HSA-6806778)
0.527
2
UniProt:P02675 FGB
5
FGB(31-491) [platelet alpha granule lumen]
(R-HSA-140921)
FGB(31-491) [extracellular region]
(R-HSA-140846)
FGB [plasma membrane]
(R-HSA-140917)
FGB(31-44) [extracellular region]
(R-HSA-140876)
FGB [extracellular region]
(R-HSA-140584)
0.527
2
UniProt:P56539 CAV3
1
CAV3 [plasma membrane]
(R-HSA-1368135)
0.527
2
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