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TAS2R7 [plasma membrane]
Stable Identifier
R-HSA-3299612
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Taste receptor type 2 member 7, TA2R7_HUMAN
Locations in the PathwayBrowser
Expand all
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
Bitter compound binds bitter taste receptor (TAS2R) (Homo sapiens)
TAS2R:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan) [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R7:ligand [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
GNAT3 exchanges GDP for GTP in TAS2R:bitter compound:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
TAS2R:ligand:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R7:ligand [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
TAS2R:ligand:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R7:ligand [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
TAS2R:bitter compound:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R7:ligand [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
TAS2R:ligand:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS2R (non-orphan):ligand [plasma membrane] (Homo sapiens)
TAS2R7:ligand [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class C/3 (Metabotropic glutamate/pheromone receptors) (Homo sapiens)
T2Rs bind bitter-tasting compounds (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
TAS2Rs:Bitter-tasting compounds [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
TAS2R7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NYW3 TAS2R7
Gene Names
TAS2R7
Chain
chain:1-318
Reference Genes
BioGPS Gene:50837 TAS2R7
COSMIC (genes):TAS2R7 TAS2R7
CTD Gene:50837 TAS2R7
dbSNP Gene:50837 TAS2R7
ENSEMBL:ENSG00000121377 TAS2R7
HGNC:14913 TAS2R7
KEGG:hsa:50837 TAS2R7
Monarch:50837 TAS2R7
NCBI Gene:50837 TAS2R7
OMIM:604793 TAS2R7
UCSC:Q9NYW3 TAS2R7
Reference Transcript
RefSeq:NM_023919.2 TAS2R7
Other Identifiers
11735859_at
16761453
221396_PM_at
221396_at
3444301
3444302
3444303
50837
7961239
A_23_P36624
GO:0001580
GO:0004930
GO:0005515
GO:0005886
GO:0007186
GO:0008527
GO:0016020
GO:0033038
GO:0050877
GO:0050909
GO:0060089
HMNXSV003051315
ILMN_1739653
PH_hs_0014065
TC12001228.hg
g12965175_3p_at
Participates
as a member of
TAS2R (non-orphan) [plasma membrane] (Homo sapiens)
TAS2Rs [plasma membrane] (Homo sapiens)
as a component of
TAS2R7:ligand [plasma membrane] (Homo sapiens)
Inferred To
Tas2r7 [plasma membrane]
(Mus musculus)
Tas2r7 [plasma membrane]
(Rattus norvegicus)
t2r14 [plasma membrane]
(Xenopus tropicalis)
t2r2 [plasma membrane]
(Xenopus tropicalis)
t2r3 [plasma membrane]
(Xenopus tropicalis)
TAS2R7 [plasma membrane]
(Bos taurus)
TAS2R7 [plasma membrane]
(Canis familiaris)
TAS2R7 [plasma membrane]
(Gallus gallus)
TAS2R7 [plasma membrane]
(Sus scrofa)
Homologues of TAS2R60 [plasma membrane]
(Danio rerio)
Homologues of TAS2R60 [plasma membrane]
(Gallus gallus)
Homologues of TAS2R60 [plasma membrane]
(Xenopus tropicalis)
tas2r200.1 [plasma membrane]
(Danio rerio)
tas2r7 [plasma membrane]
(Xenopus tropicalis)
TAS2R40 [plasma membrane]
(Gallus gallus)
t2r15 [plasma membrane]
(Xenopus tropicalis)
tas2r4 [plasma membrane]
(Xenopus tropicalis)
tas2r200.2 [plasma membrane]
(Danio rerio)
LOC101747503 [plasma membrane]
(Gallus gallus)
Cross References
RefSeq
NP_076408.1
Guide to Pharmacology - Targets
663
ENSEMBL
ENST00000240687
,
ENST00000574656
,
ENSP00000240687
,
ENSG00000274327
,
ENSG00000121377
,
ENSG00000273326
,
ENSP00000458498
,
ENST00000613239
,
ENSP00000484743
OpenTargets
ENSG00000121377
GeneCards
TAS2R7
HPA
ENSG00000121377-TAS2R7
PRO
Q9NYW3
Pharos - Targets
Q9NYW3
GlyGen
Q9NYW3
HMDB Protein
HMDBP08043
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y5K6 CD2AP
1
CD2AP [cytosol]
(R-HSA-373620)
0.527
2
UniProt:Q13490 BIRC2
5
BIRC2 [cytosol]
(R-HSA-50847)
K48pUb-BIRC2 [cytosol]
(R-HSA-5675479)
BIRC2(373-618) [cytosol]
(R-HSA-202931)
BIRC2(1-372) [cytosol]
(R-HSA-202913)
K63polyUb-BIRC2 [cytosol]
(R-HSA-5668512)
0.527
2
UniProt:P23634 ATP2B4
1
ATP2B4 [plasma membrane]
(R-HSA-418304)
0.499
2
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