Reactome | KANSL1 [nucleoplasm]

KANSL1 [nucleoplasm]

Stable Identifier

R-HSA-3321875

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KAT8 regulatory NSL complex subunit 1, KANL1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q7Z3B3 KANSL1

Gene Names

KANSL1, CENP-36, KIAA1267, MSL1V1, NSL1

Chain

chain:1-1105

Reference Genes

BioGPS Gene:284058 KANSL1

COSMIC (genes):KANSL1 KANSL1

COSMIC (genes):NSL1 KANSL1

CTD Gene:284058 KANSL1

dbSNP Gene:284058 KANSL1

ENSEMBL:ENSG00000120071 KANSL1

HGNC:24565 KANSL1

Monarch:284058 KANSL1

NCBI Gene:284058 KANSL1

OMIM:612452 KANSL1

UCSC:Q7Z3B3 KANSL1

Reference Transcript

Other Identifiers

11740615_a_at

11744432_s_at

11747413_a_at

16845973

225117_PM_at

225117_at

243589_PM_at

243589_at

284058

3723574

3723575

3723576

3760139

3760140

3760141

3760142

3760143

3760144

3760145

3760146

3760147

3760148

3760149

3760150

3760151

3760152

3760153

3760154

3760155

3760156

3760157

3760158

3760159

3760160

3760161

3760164

3760165

3760166

3760169

3760170

3760172

3760173

3760174

3760181

3760193

3760194

3760197

3760198

3760199

3760211

3760212

3760213

3760216

3760217

3760218

3760219

3760220

3760221

3760222

3760228

3760229

3760230

3760231

3760238

3760613

44791_at

64378_at

71733_at

77264_at

78263_at

8016266

80209_at

A_21_P0014030

A_23_P55376

A_33_P3235521

GE509316

GE53859

GO:0000123

GO:0000775

GO:0000776

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005739

GO:0006325

GO:0006355

GO:0035035

GO:0043226

GO:0043231

GO:0044545

GO:0045893

GO:0071339

GO:1902562

GO:1903108

HMNXSV003014327

Hs.146625.0.A1_3p_at

Hs.43141.0.S1_3p_at

ILMN_1678235

ILMN_2200636

PH_hs_0003151

RNA147120|p0224_imsncRNA344

TC17001610.hg

TC17_ctg5_hap1000005.hg

TC17_ctg5_hap1000008.hg

Participates

as a component of

as an input of

Formation of the NSL complex (Homo sapiens)

Inferred To

nsl1 [nucleoplasm] (Drosophila melanogaster)

kansl1 [nucleoplasm] (Xenopus tropicalis)

KANSL1 [nucleoplasm] (Bos taurus)

KANSL1 [nucleoplasm] (Canis familiaris)

KANSL1 [nucleoplasm] (Gallus gallus)

KANSL1 [nucleoplasm] (Sus scrofa)

Kansl1 [nucleoplasm] (Mus musculus)

Kansl1 [nucleoplasm] (Rattus norvegicus)

kansl1b [nucleoplasm] (Danio rerio)

Cross References

OpenTargets

ENSG00000120071

ENSEMBL

ENSP00000461484, ENST00000432791, ENST00000262419, ENST00000572904, ENSP00000387393, ENSP00000262419

HPA

ENSG00000120071-KANSL1

PRO

Q7Z3B3

Pharos - Targets

Q7Z3B3

GlyGen

Q7Z3B3

Orphanet

KANSL1

PDB

4CY2, 4CY1

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.915	13
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.742	5
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.742	5
UniProt:Q13137 CACO2			0.742	5
UniProt:Q9H9L4 KANSL2	1	KANSL2 [nucleoplasm] (R-HSA-3321796)	0.688	4
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.667	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.666	4
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.666	4
UniProt:Q9BVG8 KIFC3			0.666	4
UniProt:P37198 NUP62	2	NUP62 [nuclear envelope] (R-HSA-157713) NUP62 [cytosol] (R-HSA-9634226)	0.666	4
UniProt:Q01850 CDR2			0.666	4
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.666	4
UniProt:Q96ED9 HOOK2			0.666	4
UniProt:Q01167 FOXK2	1	FOXK2 [nucleoplasm] (R-HSA-5689655)	0.643	4
UniProt:Q9D1P2	1	KAT8 [nucleoplasm] (R-MMU-3321802)	0.564	2
UniProt:Q96EV8 DTNBP1	1	DTNBP1 [cytosol] (R-HSA-429819)	0.556	3
UniProt:Q9BUZ4 TRAF4			0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:Q96R06 SPAG5			0.556	3
UniProt:Q8ND90 PNMA1			0.556	3
UniProt:A1L4K1 FSD2			0.556	3
UniProt:P43365 MAGAC			0.556	3
UniProt:Q86Y26 NUTM1			0.556	3
UniProt:Q7Z6G3-2 NECAB2			0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199)	0.553	2
UniProt:Q9BVI0 PHF20	2	p-S291-PHF20 [nucleoplasm] (R-HSA-6805776) PHF20 [nucleoplasm] (R-HSA-3222239)	0.527	3
UniProt:Q9NX74 DUS2	1	DUS2 [cytosol] (R-HSA-6782261)	0.527	2
UniProt:A8MW92 PHF20L1	1	PHF20L1 [nucleoplasm] (R-HSA-9828235)	0.527	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.527	2
UniProt:Q15834 CC85B			0.508	2

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