Reactome | KANSL1 [nucleoplasm]

KANSL1 [nucleoplasm]

Stable Identifier

R-HSA-3321875

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

KAT8 regulatory NSL complex subunit 1, KANL1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8ND90 PNMA1

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External Reference Information

External Reference

UniProt:Q7Z3B3 KANSL1

Gene Names

KANSL1, CENP-36, KIAA1267, MSL1V1, NSL1

Chain

chain:1-1105

Reference Genes

BioGPS Gene:284058 KANSL1

COSMIC (genes):KANSL1 KANSL1

CTD Gene:284058 KANSL1

dbSNP Gene:284058 KANSL1

ENSEMBL:ENSG00000120071 KANSL1

ENSEMBL_homo_sapiens_GENE:ENSG00000120071.15 KANSL1

HGNC:24565 KANSL1

KEGG Gene (Homo sapiens):284058 KANSL1

Monarch:284058 KANSL1

NCBI Gene:284058 KANSL1

OMIM:612452 KANSL1

UCSC:Q7Z3B3 KANSL1

Reference Transcript

Other Identifiers

11740615_a_at

11744432_s_at

11747413_a_at

16845973

225117_PM_at

225117_at

284058

3723575

3760139

3760140

3760141

3760142

3760144

3760145

3760146

3760147

3760149

3760154

3760155

3760156

3760158

3760161

3760164

3760165

3760166

3760169

3760173

3760212

3760213

3760216

3760217

3760218

3760219

3760220

3760221

3760222

3760230

44791_at

64378_at

77264_at

78263_at

8016266

A_23_P55376

GE509316

GE53859

GO:0000123

GO:0000775

GO:0000776

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0006351

GO:0006355

GO:0035035

GO:0036211

GO:0043226

GO:0044545

GO:0045893

GO:0051571

GO:0071339

HMNXSV003014327

Hs.43141.0.S1_3p_at

ILMN_1678235

ILMN_2200636

PH_hs_0003151

TC17001610.hg

TC17_ctg5_hap1000005.hg

TC17_ctg5_hap1000008.hg

Participates

as a component of

as an input of

Formation of the NSL complex (Homo sapiens)

Inferred To

nsl1 [nucleoplasm] (Drosophila melanogaster)

kansl1 [nucleoplasm] (Xenopus tropicalis)

KANSL1 [nucleoplasm] (Bos taurus)

KANSL1 [nucleoplasm] (Canis familiaris)

KANSL1 [nucleoplasm] (Gallus gallus)

KANSL1 [nucleoplasm] (Sus scrofa)

Kansl1 [nucleoplasm] (Mus musculus)

Kansl1 [nucleoplasm] (Rattus norvegicus)

kansl1b [nucleoplasm] (Danio rerio)

Cross References

RefSeq

NP_056258.1, XP_006721886.1, NP_001180395.1, NP_001180394.1, XP_006721887.1

OpenTargets

ENSG00000120071

GeneCards

Q7Z3B3

HPA

ENSG00000120071-KANSL1

Ensembl

ENSG00000120071, ENST00000432791, ENSP00000461484, ENST00000572904, ENSP00000262419, ENSP00000387393, ENST00000262419

PRO

Q7Z3B3

Pharos - Targets

Q7Z3B3

Orphanet

21173

PDB

4CY2, 4CY1

Interactors (30)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.915	13
UniProt:Q13137 CACO2			0.742	5
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.742	5
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.742	5
UniProt:Q9H9L4 KANSL2	1	KANSL2 [nucleoplasm] (R-HSA-3321796)	0.688	4
UniProt:Q99459 CDC5L	1	CDC5L [nucleoplasm] (R-HSA-5420887)	0.667	3
UniProt:Q96ED9 HOOK2			0.666	4
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.666	4
UniProt:Q01850 CDR2			0.666	4
UniProt:P37198 NUP62	2	NUP62 [cytosol] (R-HSA-9634226) NUP62 [nuclear envelope] (R-HSA-157713)	0.666	4
UniProt:Q9BVG8 KIFC3			0.666	4
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.666	4
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.666	4
UniProt:Q01167 FOXK2	1	FOXK2 [nucleoplasm] (R-HSA-5689655)	0.643	4
UniProt:Q9D1P2	1	KAT8 [nucleoplasm] (R-MMU-3321802)	0.564	2
UniProt:Q7Z6G3-2 NECAB2			0.556	3
UniProt:Q86Y26 NUTM1			0.556	3
UniProt:P43365 MAGAC			0.556	3
UniProt:A1L4K1 FSD2			0.556	3
UniProt:Q8ND90 PNMA1			0.556	3
UniProt:Q96R06 SPAG5			0.556	3
UniProt:Q96JN2-2 CCDC136			0.556	3
UniProt:Q9BUZ4 TRAF4			0.556	3
UniProt:Q96EV8 DTNBP1	1	DTNBP1 [cytosol] (R-HSA-429819)	0.556	3
UniProt:Q12933 TRAF2	5	TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) PolyUb-TRAF2 [cytosol] (R-HSA-6782848) TRAF2 [cytosol] (R-HSA-66370)	0.553	2
UniProt:A8MW92 PHF20L1	1	PHF20L1 [nucleoplasm] (R-HSA-9828235)	0.527	3
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.527	2
UniProt:Q9BVI0 PHF20	2	PHF20 [nucleoplasm] (R-HSA-3222239) p-S291-PHF20 [nucleoplasm] (R-HSA-6805776)	0.527	3
UniProt:Q9NX74 DUS2	1	DUS2 [cytosol] (R-HSA-6782261)	0.527	2
UniProt:Q15834 CC85B			0.508	2

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