Reactome | EPC1 [nucleoplasm]

EPC1 [nucleoplasm]

Stable Identifier

R-HSA-3321978

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Enhancer of polycomb homolog 1, EPC1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9H2F5 EPC1

Gene Names

EPC1

Chain

chain:1-836

Reference Genes

BioGPS Gene:80314 EPC1

COSMIC (genes):EPC1 EPC1

CTD Gene:80314 EPC1

dbSNP Gene:80314 EPC1

ENSEMBL:ENSG00000120616.16 EPC1

HGNC:19876 EPC1

KEGG Gene (Homo sapiens):80314 EPC1

Monarch:80314 EPC1

NCBI Gene:80314 EPC1

OMIM:610999 EPC1

UCSC:Q9H2F5 EPC1

Reference Transcript

Other Identifiers

0001230398

11736740_a_at

11759563_a_at

16713113

223875_PM_s_at

223875_s_at

225417_PM_at

225417_at

234969_PM_s_at

234969_s_at

3284082

3284083

3284084

3284085

3284086

3284087

3284090

3284091

3284092

3284093

3284097

3284098

3284099

3284100

3284101

3284102

3284103

3284105

3284107

3284108

3284112

3284113

3284124

3284125

3284126

3284127

3284137

45486_s_at

65537_at

76053_at

7932938

80314

A_23_P46725

A_24_P252718

GE62683

GE87187

GO:0000122

GO:0000724

GO:0000786

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005654

GO:0005694

GO:0005737

GO:0006281

GO:0006310

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0007283

GO:0008150

GO:0012501

GO:0016573

GO:0022414

GO:0030154

GO:0030674

GO:0031965

GO:0032777

GO:0032991

GO:0035267

GO:0040008

GO:0042981

GO:0043226

GO:0043231

GO:0043967

GO:0043968

GO:0045814

GO:0045892

GO:0045893

GO:0045944

GO:0051726

GO:0140463

GO:1905168

GO:2000779

HMNXSV003034924

HMNXSV003045550

Hs.129998.1.A1_3p_at

ILMN_1746276

PH_hs_0025918

TC10001161.hg

TC10002548.hg

g11907922_3p_a_at

Participates

as a component of

as an input of

E2F6:TFDP1 binds EPC1 (Homo sapiens)

Inferred To

epc1 [nucleoplasm] (Xenopus tropicalis)

EPC1 [nucleoplasm] (Bos taurus)

EPC1 [nucleoplasm] (Canis familiaris)

EPC1 [nucleoplasm] (Dictyostelium discoideum)

EPC1 [nucleoplasm] (Gallus gallus)

EPC1 [nucleoplasm] (Sus scrofa)

E(Pc) [nucleoplasm] (Drosophila melanogaster)

LOC566102 [nucleoplasm] (Danio rerio)

Epc1 [nucleoplasm] (Mus musculus)

Epc1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_079485.1, NP_001258948.1, NP_001269320.1, NP_001258933.1

OpenTargets

ENSG00000120616

GeneCards

Q9H2F5

HPA

ENSG00000120616-EPC1

Ensembl

ENSG00000120616, ENSP00000364251, ENST00000375110, ENSP00000263062, ENST00000263062, ENST00000319778, ENSP00000318559

PRO

Q9H2F5

Pharos - Targets

Q9H2F5

PDB

6NFX

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.696	5
UniProt:Q9NV56 MRGBP	1	MRGBP [nucleoplasm] (R-HSA-3322953)	0.643	5
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.556	3
UniProt:Q15906 VPS72	1	VPS72 [nucleoplasm] (R-HSA-3321992)	0.527	3
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.527	4
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.527	3
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.527	3
UniProt:Q05BQ5 MBTD1			0.525	6
UniProt:Q9H0E9 BRD8	1	BRD8 [nucleoplasm] (R-HSA-3321977)	0.499	5
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.483	2

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