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EP400 [nucleoplasm]
Stable Identifier
R-HSA-3321987
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
E1A-binding protein p400, EP400_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q15014 MORF4L2
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
DNA Damage/Telomere Stress Induced Senescence (Homo sapiens)
EP400 binds CDKN1A promoter (Homo sapiens)
EP400 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q96L91 EP400
Gene Names
EP400, CAGH32, KIAA1498, KIAA1818, TNRC12
Chain
chain:1-3159
Reference Genes
BioGPS Gene:57634 EP400
COSMIC (genes):EP400 EP400
CTD Gene:57634 EP400
dbSNP Gene:57634 EP400
ENSEMBL:ENSG00000183495 EP400
ENSEMBL_homo_sapiens_GENE:ENSG00000183495.15 EP400
HGNC:11958 EP400
KEGG Gene (Homo sapiens):57634 EP400
Monarch:57634 EP400
NCBI Gene:57634 EP400
OMIM:606265 EP400
UCSC:Q96L91 EP400
Reference Transcript
RefSeq:NM_015409.4 EP400
Other Identifiers
11717230_a_at
11717231_at
11750113_a_at
11754714_a_at
11755409_a_at
11757980_s_at
16759411
212375_PM_at
212375_at
212376_PM_s_at
212376_s_at
230628_PM_at
230628_at
230629_PM_s_at
230629_s_at
3438618
3438622
3438623
3438624
3438625
3438626
3438627
3438632
3438633
3438634
3438635
3438636
3438637
3438642
3438643
3438644
3438647
3438650
3438651
3438652
3438653
3438656
3438659
3438660
3438661
3438662
3438663
3438664
3438665
3438666
3438671
3438672
3438675
3438676
3438677
3438678
3438679
3438683
3438684
3438685
3438686
3438687
3438689
3438693
3438694
3438695
3438699
3438700
3438703
3438704
3438705
3438706
3438708
3438709
3438711
3438712
3438714
3438715
3438719
3438721
3438722
3438723
3438724
3438725
3438730
3438731
3438733
3438734
3438737
3438739
3438742
3438746
3438747
3438757
3438759
3438760
3438761
3438762
3438763
3438764
3438765
3438766
3438767
3438769
3438771
3438773
3438774
3438775
3438793
3438794
3438795
3438796
3438818
34815_at
34816_at
43428_at
47518_at
57634
72958_at
7959995
89622_r_at
A_14_P112055
A_14_P127904
A_23_P253158
A_23_P421465
A_24_P298939
GE59464
GE848480
GO:0000166
GO:0000228
GO:0000786
GO:0000812
GO:0003677
GO:0003682
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0006281
GO:0006310
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0012501
GO:0016607
GO:0016787
GO:0035267
GO:0042981
GO:0043226
GO:0045893
GO:0051726
GO:0140097
GO:0140657
GO:0140658
GO:1905168
GO:1990405
GO:2000779
HMNXSV003029813
Hs.14291.0.A1_3p_at
Hs.306094.0.S1_3p_a_at
Hs.306094.0.S2_3p_at
ILMN_1673023
PH_hs_0015720
TC12001051.hg
Participates
as a component of
NuA4 [nucleoplasm] (Homo sapiens)
EP400:p-S15-TP53 Tetramer:CDKN1A Gene [nucleoplasm] (Homo sapiens)
as an input of
EP400 binds CDKN1A promoter (Homo sapiens)
Inferred To
EAF1 [nucleoplasm]
(Saccharomyces cerevisiae)
ep400 [nucleoplasm]
(Xenopus tropicalis)
vid21 [nucleoplasm]
(Schizosaccharomyces pombe)
EP400 [nucleoplasm]
(Bos taurus)
EP400 [nucleoplasm]
(Canis familiaris)
EP400 [nucleoplasm]
(Gallus gallus)
EP400 [nucleoplasm]
(Mus musculus)
EP400 [nucleoplasm]
(Sus scrofa)
Ep400 [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
NP_056224.3
OpenTargets
ENSG00000183495
HPA
ENSG00000183495-EP400
GeneCards
Q96L91
Ensembl
ENSG00000183495
,
ENSP00000374212
,
ENST00000389561
PRO
Q96L91
Pharos - Targets
Q96L91
Interactors (23)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.763
6
UniProt:Q9Y230 RUVBL2
1
RUVBL2 [nucleoplasm]
(R-HSA-418321)
0.744
5
UniProt:Q9NV56 MRGBP
1
MRGBP [nucleoplasm]
(R-HSA-3322953)
0.725
5
UniProt:Q9Y265 RUVBL1
1
RUVBL1 [nucleoplasm]
(R-HSA-418323)
0.725
7
UniProt:P13196 ALAS1
2
PXLP-ALAS1 [mitochondrial matrix]
(R-HSA-1022086)
ALAS1 [mitochondrial matrix]
(R-HSA-189438)
0.666
4
UniProt:Q6PJQ5 FOXR2
0.643
3
UniProt:Q6PIV2 FOXR1
0.643
4
UniProt:P09874 PARP1
4
polySUMO2,3-K203,K486-PARP1 [nucleoplasm]
(R-HSA-4551617)
monoSUMO1-K203,K486-PARP1 [nucleoplasm]
(R-HSA-4551686)
PAR-PARP1 [nucleoplasm]
(R-HSA-5651713)
PARP1 [nucleoplasm]
(R-HSA-201568)
0.564
2
UniProt:O96019 ACTL6A
1
ACTL6A [nucleoplasm]
(R-HSA-2980912)
0.564
3
UniProt:Q9H0E9 BRD8
1
BRD8 [nucleoplasm]
(R-HSA-3321977)
0.564
3
UniProt:P01100 FOS
2
FOS [nucleoplasm]
(R-HSA-450216)
p-T325,T331,S362,S374-FOS [nucleoplasm]
(R-HSA-450283)
0.536
2
UniProt:P61244 MAX
1
MAX [nucleoplasm]
(R-HSA-3006627)
0.527
2
UniProt:P03372 ESR1
10
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
ESR1 [nucleoplasm]
(R-HSA-446168)
ESR1 [cytosol]
(R-HSA-9020968)
0.527
3
UniProt:P0C0S5 H2AZ1
1
H2AFZ [extracellular region]
(R-HSA-977575)
0.527
4
UniProt:Q92993-2 KAT5
0.527
2
UniProt:Q96A08 H2BC1
9
HIST1H2BA [nucleoplasm]
(R-HSA-181916)
Ub-122-HIST1H2BA [nucleoplasm]
(R-HSA-3364020)
AcK22-HIST1H2BA [nucleoplasm]
(R-HSA-4568647)
AcK17-HIST1H2BA [nucleoplasm]
(R-HSA-4568631)
AcK14-HIST1H2BA [nucleoplasm]
(R-HSA-4568615)
AcK7-HIST1H2BA [nucleoplasm]
(R-HSA-4568624)
HIST1H2BA [extracellular region]
(R-HSA-977582)
AcK-HIST1H2BA [nucleoplasm]
(R-HSA-4549263)
Ub-HIST1H2BA [nucleoplasm]
(R-HSA-6782561)
0.527
4
UniProt:O95619 YEATS4
1
YEATS4 [nucleoplasm]
(R-HSA-3322940)
0.527
3
UniProt:Q15014 MORF4L2
1
MORF4L2 [nucleoplasm]
(R-HSA-3322945)
0.527
3
UniProt:Q99909 SSX3
0.527
2
UniProt:Q9HBJ0 PLAC1
0.527
2
UniProt:Q9Y463 DYR1B
0.527
2
UniProt:P52630 STAT2
4
p-Y690-STAT2 [cytosol]
(R-HSA-909683)
STAT2 [cytosol]
(R-HSA-882029)
p-Y690-STAT2 [nucleoplasm]
(R-HSA-909673)
p-Y-STAT2 [cytosol]
(R-HSA-8987235)
0.527
3
UniProt:Q86VZ6 JAZF1
0.483
3
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